Rhodococcus sp. DN22: RA302_11700
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Entry
RA302_11700 CDS
T09949
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
rhoo
Rhodococcus sp. DN22
Pathway
rhoo00290
Valine, leucine and isoleucine biosynthesis
rhoo00660
C5-Branched dibasic acid metabolism
rhoo01100
Metabolic pathways
rhoo01110
Biosynthesis of secondary metabolites
rhoo01210
2-Oxocarboxylic acid metabolism
rhoo01230
Biosynthesis of amino acids
Module
rhoo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rhoo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
RA302_11700 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RA302_11700 (leuC)
Enzymes [BR:
rhoo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
RA302_11700 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
RA302_11700 (leuC)
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Motif
Pfam:
Aconitase
AcnX
DUF6127
Motif
Other DBs
NCBI-ProteinID:
WVX72839
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Position
2550354..2551775
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AA seq
473 aa
AA seq
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MEDMAQKARTLAEKVWDDHVVVKGEGQDPDLIYIDLHLVHEVTSPQAFDGLRLAGRPLRR
PDLTIATEDHNVPTIDIDKPIADPVSKTQVDTLRRNCEEFGVRLHRMGDLDQGIVHVVGP
QLGLTQPGTTVVCGDSHTSTHGAFGALAMGIGTSEVEHVMATQTLSLRPFKTMAITVDGE
LPPGVTSKDLILAVIAKIGTGGGQGYVLEYRGEAIRKLSMEARMTICNMSIEAGARAGMI
APDETTYEFIKGRPHAPSGAEWDEAVAAWELLKTDEGAEFDNEVHIDASALTPFVTWGTN
PGQGAPLGDRVPDPELIVDESERQAAEKALTYMGLDAGMALRDVAVDTVFVGSCTNGRIE
DLRAVAEVLEGRHVAEGVRMLIVPGSMRVRAQAESEGLGEIFTAAGAEWRQAGCSMCLGM
NPDQLAPGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSAPADLV
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtggaagacatggcacagaaagcacgcactctcgccgagaaggtgtgggacgaccacgtt
gtcgtgaaaggggaggggcaggatcccgacctcatctacatcgatctccacctcgttcac
gaagtgacgagcccgcaggccttcgacggacttcgcttggcaggacgcccgttgcgccgt
cccgacctgacgatcgccaccgaggaccacaatgttccgacgatcgacatcgacaagccg
atcgccgatcccgtgtccaagactcaggtcgacaccttgcgccgaaattgcgaagaattc
ggagttcgcttgcaccgcatgggcgatctcgatcagggcatcgtgcatgtggtcggaccg
cagctcggcctgactcagccgggaaccaccgtggtgtgcggcgacagtcatacgtcgacg
cacggcgcattcggtgcgctcgcaatgggaatcggcaccagcgaggtcgagcacgtgatg
gcgacgcagacattgtcgttgcgccccttcaagaccatggcgatcacggtcgacggcgag
ctgcctcctggcgtcacgagcaaggacttgatcctggcagtcatcgccaagatcggcacc
ggcggcggccagggctacgtcctggagtaccgcggcgaggccattcgcaaactgtcgatg
gaagctcgtatgaccatctgcaacatgtcgatcgaggccggagcccgtgcgggcatgatc
gcaccggacgagaccacttacgagttcataaagggccgtccgcatgcaccgtcgggcgca
gagtgggacgaagccgtcgccgcgtgggagttgctcaagaccgacgagggcgccgaattc
gacaacgaggtccacatcgacgcaagcgcattgacgccttttgtcacgtggggaaccaat
ccgggacagggtgcaccgctcggtgaccgagtgcccgatccggaactgatcgtcgacgag
agcgagcgtcaggctgccgagaaggcgctcacctacatgggtctcgacgccggcatggcg
cttcgggatgttgctgtcgacaccgtcttcgtcggttcgtgcaccaacggacgcatcgaa
gatctgcgcgcggtggccgaggtgctcgagggtcgccatgtggcagagggcgttcggatg
ctcatcgttcccggctcgatgcgggtgcgtgctcaagccgaaagtgaaggtctcggtgaa
atcttcacggcggcaggggccgaatggcgccaggccggttgctcgatgtgcttgggaatg
aaccctgaccagcttgctcccggcgagcgttcggcatcgacgtccaaccggaatttcgaa
ggccgacagggtaaaggcggtcggacccatctggtttccccgctcgtcgcggctgccact
gcggtccgcggaacgctctcggcaccggccgatctggtctga
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