Rhodococcus sp. DN22: RA302_17010
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Entry
RA302_17010 CDS
T09949
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhoo
Rhodococcus sp. DN22
Pathway
rhoo00300
Lysine biosynthesis
rhoo00550
Peptidoglycan biosynthesis
rhoo01100
Metabolic pathways
rhoo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhoo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
RA302_17010 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
RA302_17010 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
RA302_17010 (murF)
Enzymes [BR:
rhoo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
RA302_17010 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NodS
Motif
Other DBs
NCBI-ProteinID:
WVX68218
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Position
complement(3751765..3753333)
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AA seq
522 aa
AA seq
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MIPMTLSRIAEIVGGTLHDVDDSSTQVTGTVEFDSRKVAPGGLFLALPGARVDGHDHAEA
AVAAGAVAVLAARPVGVPAIVVPSVPNDGPSAVMLLEHDTDGSGAAVLHALGLLARAVVD
ELATDGTPADGGLTLVGVTGSAGKTSTKDLIAALLRECGEVVAPPGSFNNELGLPWTVLR
ADEKTRFLVLEMSARGVGHVGELTKIAPPKIGVVLNVGTAHLGEFGSREAIAVAKGELVE
ALPSAADGGVAVLNADDRMVAAMASRTKARIVFVGQSEDCDVRATDVVVDDQARASFTLN
CSQGSARIRLAVHGEHHVSNALAAAAVALENGLAVTDIARVLEGTKAASARRMEVTERAD
GVTVVNDSYNANPDSMRAALKALVSMARSDRHFGRRSWAVLGEMGELGPESVVEHDAIGR
LAVRLDVSKLIVVGTGRTSRAMHQGAVMEGSWGDESVVVPDAAAAIAILEAELEPGDLVL
VKASKSVELWTVAEAILAATPNTDSENTDSENTDGENGGDSQ
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacgctctctcggatcgccgagatcgtcggaggaaccctgcacgacgtc
gacgattcgtcgacgcaggtgactggaaccgtcgaattcgattcgcgcaaagtagctcca
ggtgggctcttcctcgccctacccggagcgcgtgtcgacggtcatgatcacgcggaagcg
gcggtggcagcgggcgctgtggcggtgctcgcggcgcggccggtcggagttccggcaatc
gtcgttccatcggtgccgaacgacggtcccagtgcagtgatgctgctcgaacacgacacc
gacgggtccggagccgcggtcctgcatgccctcggccttctggcccgagcagtcgtcgac
gaactggcaactgatggcacaccggccgatggtggactgacgctggtcggtgtcactggt
tctgccggcaagacctcgaccaaggatctgatagcagcgctgctgcgcgagtgcggcgag
gtggttgcgccccccgggtcgttcaacaacgaattgggtctgccgtggacagtgctccgc
gccgacgagaagacccgcttcctcgttctcgagatgtcggcccgtggggtcggtcatgtc
ggcgaactgacgaagatcgcgccgccgaagatcggcgtagttctcaatgtgggcactgcc
catctcggtgagttcggttcgcgtgaagcgatcgcggtcgccaaaggtgaactggtggaa
gcactcccgtcggcagccgacggtggagttgcggtcctcaacgccgacgaccgcatggtc
gccgcaatggcgagtcgaaccaaggcccggatcgtattcgtcggccagtcggaagactgc
gacgttcgggcgaccgacgtggttgtcgacgaccaggccagggcttccttcacactgaac
tgttcacagggttctgcacgtattcgcctggccgttcacggcgaacaccacgtgagcaac
gccctggccgcggcggccgtcgcactcgagaacggcctcgcggttacagacatcgcacgt
gtcctcgagggcacgaaggcagcgtccgcgaggcggatggaagtcaccgagcgcgccgac
ggcgtcaccgtcgtcaacgacagttacaacgccaatcccgattccatgcgcgctgcgctc
aaagcgttggtgtccatggcgcgatcggatcggcacttcggtcgccgtagctgggctgtg
ctcggagagatgggtgagctcggaccggaatcagttgtcgagcacgacgcgatcggtcgc
ctggccgtcagactcgatgtcagcaagttgatcgtcgtcgggacgggccgcacctcgcgt
gcaatgcatcaaggagcagtgatggaggggtcgtggggtgacgagtccgtcgtcgtgccc
gacgcagctgcggcaatcgccattctcgaagcggaactcgaaccgggcgatctcgtcctg
gtgaaggcgtccaagtcggtggaactgtggacggtcgccgaagcgatactggctgcaacg
cccaacaccgacagcgagaacaccgacagcgagaacaccgatggcgagaacggcggggat
tcgcagtga
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