Rhodococcus sp. P1Y: D8W71_18740
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Entry
D8W71_18740 CDS
T09477
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhop
Rhodococcus sp. P1Y
Pathway
rhop00300
Lysine biosynthesis
rhop00550
Peptidoglycan biosynthesis
rhop01100
Metabolic pathways
rhop01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhop00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
D8W71_18740
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
D8W71_18740
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
D8W71_18740
Enzymes [BR:
rhop01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
D8W71_18740
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AYJ49995
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Position
complement(4077162..4078700)
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AA seq
512 aa
AA seq
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MKALTIAQIAEIVGGQLHDVDDPTRLVDGTVEFDSRKVTAGGLFLALPGARVDGHDHAAA
AIASGAAVVLAARPVGVPAIVVEPVPHDGRAMALEHDVDGSGAAVLTALSALARASALEL
TAHAGLTVLGVTGSSGKTSTKDLIASVLRPLGAVVAPPGSFNNELGHPWTVLRADESSDF
LVLELSARGIGHVAALARAAPPRIGVVLNVGTAHLGEFGSRERIALAKGELVEALPSAAD
GGVAVLNADDRLVLEMRSRTSARVVTVGLSPEADIRAENVSLDANARARFTMVTPVGSID
IALAVHGEHQVGNALAAAAVALECGATLDQISSALAGSSAASVRRMDVSTRTDGVTVVND
SYNANPDSMRAALKALVSMSRSGTGSRRRTWAVLGEMGELGPESVTEHDAIGRLAVRLDV
SRLVIVESGRPTRAMHQGAVMEGSWGEESMLVPDKESAIAVLRDQLEPGDIVLVKASQSV
ALWSVADALLDNETVPDAGNGERDIMTAEESQ
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
gtgaaagcactgaccatcgcgcagattgccgagatcgtcggtggtcagctccacgacgtc
gacgatccaacccgtctcgtcgatggaacggtcgagttcgattctcgcaaggtgacggct
ggaggactcttcctcgccttgcctggtgcacgggtggacgggcacgatcacgcagccgca
gcaatcgcgtcgggtgcggccgtggttcttgccgctcgaccggtcggagtaccagccatc
gtcgtcgaaccggtcccgcacgatggccgtgccatggcactggaacacgacgtcgacggc
tcgggcgccgctgtactgaccgcgctcagtgccttggcccgtgcgtctgcgctggagctg
accgcgcatgccggcctcacggtgctcggggtgacgggctcgtcgggaaagacctcgacc
aaggatttgatcgcgtccgtactgaggccgctgggtgcggtcgtagcaccgccgggctcg
ttcaacaacgaactcggacacccgtggaccgtcctccgtgccgacgagtcctcggatttt
ctcgtgctcgaactgtcggcccgcggcatcggccacgtagcagccctggcgcgagcagcc
ccgccgaggataggcgtcgtactcaacgtcggtactgcccatctgggtgaattcggctca
cgagaacgaatcgcactggccaaaggcgaactcgtcgaagcacttccgagtgcggccgac
ggcggcgtcgcagtgttgaatgccgacgaccggctggtgctcgagatgcggtcgagaaca
tcggcgcgtgtggtgaccgtcggcctgtccccagaggcggacatccgcgcggagaacgtc
tcgctcgacgcgaacgcgcgcgctcgattcacgatggtgactcccgtggggtcgatcgac
atcgccttggccgtccacggtgagcatcaggtcggaaacgcactcgccgcggccgcggtc
gctctcgagtgcggcgcgacgctcgatcagatctcgtctgcgctcgccggttcgtccgct
gcatcggtgcgcaggatggacgtctccacgcgaacggacggcgtcaccgtcgtcaacgat
tcctacaatgccaatccggattcgatgcgggctgcgttgaaagcccttgtctcgatgtcc
agatcgggcactggatccaggcggcgtacctgggccgttctaggtgaaatgggcgagcta
ggaccggagtcggtcaccgagcacgacgctatcggtaggttggccgttcgcctcgacgta
agccgactcgtcatcgtcgagtcagggcgaccgacgagggcgatgcaccagggagctgtg
atggaggggtcctggggtgaggaatcgatgttggttcccgacaaggaatcggcaatcgcg
gttctgcgcgatcagctcgagcccggggacatcgtattggtgaaagcatcgcagtcggtc
gcgctgtggtcggtggcggacgcccttctcgacaacgagactgtgccggacgccggaaac
ggggagagggacatcatgacagcggaggaatcacagtga
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