Rhodococcus sp. RCBS9: P0M12_29275
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Entry
P0M12_29275 CDS
T11459
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhrc Rhodococcus sp. RCBS9
Pathway
rhrc00300
Lysine biosynthesis
rhrc00550
Peptidoglycan biosynthesis
rhrc01100
Metabolic pathways
rhrc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhrc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
P0M12_29275
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
P0M12_29275
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
P0M12_29275
Enzymes [BR:
rhrc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
P0M12_29275
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
NodS
Motif
Other DBs
NCBI-ProteinID:
WEX03656
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Position
complement(6299073..6300641)
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AA seq
522 aa
AA seq
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MIPMTLSRIAEIVGGTLHDVDDSSTQVTGTVEFDSRKVAPGGLFLALPGARVDGHDHAEA
AVAAGAVAVLAARPVGVPAIVVPSVPNDGPSAVMLLEHDTDGSGAAVLHALGLLARAVVD
ELATDGTPADGGLTLVGVTGSAGKTSTKDLIAALLRECGEVVAPPGSFNNELGLPWTVLR
ADEKTRFLVLEMSARGVGHVGELTKIAPPKIGVVLNVGTAHLGEFGSREAIAVAKGELVE
ALPSAADGGVAVLNADDRMVAAMASRTKARIVFVGQSEDCDVRATDVVVDDQARASFTLN
CSQGSARIRLAVHGEHHVSNALAAAAVALENGLAVADIARVLEGTKAASARRMEVTERAD
GVTVVNDSYNANPDSMRAALKALVSMARSDRHFGRRSWAVLGEMGELGPESVVEHDAIGR
LAVRLDVSKLIVVGTGRTSRAMHQGAVMEGSWGDESVVVPDAAAAIAILEAELEPGDLVL
VKASKSVELWTVAEAILAATPNTDSENTGDANTAGENGGDSQ
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacgctctctcggatcgccgagatcgtcggaggaaccctgcacgacgtc
gacgattcgtcgacgcaggtgactggaaccgtcgaattcgattcgcgcaaagtagctcca
ggtgggctcttcctcgccctacccggagcgcgtgtcgacggtcatgatcacgcggaagcg
gcggtggcagcgggcgctgtggcggtgctcgcggcgcggccggtcggagttccggcaatc
gtcgttccatcggtgccgaacgacggtcccagtgcagtgatgctgctcgaacacgacacc
gacgggtccggagccgcggtcctgcatgccctcggccttctggcccgagcagtcgtcgac
gaactggcaactgatggcacaccggccgatggtggactgacgctggtcggtgtcaccggt
tctgccggcaagacctcgaccaaggatctgatagcagcgctgctgcgcgagtgcggcgag
gtggttgcgccccccgggtcgttcaacaacgaattgggtctgccgtggacagtgctccgt
gccgacgagaagacccgcttcctcgttctcgagatgtcggcccgtggggtcggtcatgtc
ggcgaactgacgaagatcgcgccgccgaagatcggcgtagttctcaatgtgggcactgcc
catctcggtgagttcggttcgcgtgaagcgatcgcggtcgccaaaggtgaactggtggaa
gcactcccgtcggcagccgacggtggagttgcggtcctcaacgccgacgaccgcatggtc
gccgcaatggcgagtcgaaccaaggcccggatcgtattcgtcggtcagtcggaagactgc
gacgttcgggcgaccgacgtggttgtcgacgaccaggccagggcttccttcacactgaac
tgttcacagggttctgcacgtattcgcctggccgttcacggcgaacaccacgtgagcaac
gccctggccgcggcggccgtcgcactcgagaacggcctcgcggttgcagacatcgcccgt
gtcctcgagggcacgaaggcagcgtccgcgaggcggatggaagtcaccgagcgcgccgac
ggcgtcaccgtcgtcaacgacagttacaacgccaatcccgattccatgcgcgccgccctc
aaagcgttggtgtccatggcgcgatcggatcggcacttcggtcgccgtagctgggctgtg
ctcggagagatgggtgagctcggaccggaatcagttgtcgagcacgacgcgatcggtcgc
ctggccgtcagactcgatgtcagcaagttgatcgtcgtcggaacgggccgcacctcgcgt
gcgatgcatcaaggagcagtgatggaggggtcgtggggtgacgagtccgtcgtcgtgccc
gacgcagctgcggcaatcgccattctcgaagcggaactcgaaccgggcgatctcgtcctg
gtgaaggcgtccaagtcggttgaactgtggacggtcgccgaagcgatactggctgcaacg
cccaacaccgacagcgagaacaccggtgacgcgaacaccgctggcgagaacggcggggat
tcgcagtga
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