Rhodococcus sp. WAY2: GFS60_02673
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Entry
GFS60_02673 CDS
T11412
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhwy Rhodococcus sp. WAY2
Pathway
rhwy00300
Lysine biosynthesis
rhwy00550
Peptidoglycan biosynthesis
rhwy01100
Metabolic pathways
rhwy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhwy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GFS60_02673 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GFS60_02673 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GFS60_02673 (murF)
Enzymes [BR:
rhwy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GFS60_02673 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QHE69117
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Position
2774746..2776260
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AA seq
504 aa
AA seq
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MIPMTLARIAQIVGGELHDVVDPSTEVTGSVEFDSRKVGPGGLFLALPGARVDGHDHAAA
AVAAGASAVVAARPVGVPAVVVPPIPVDVPSRAMALEHDSDGSGAAVLAALAKLARASVD
ELTDKGLTVVGVTGSAGKTSTKDLLAAVLRPLGPVVAPPGSFNNELGHPWTALRADADTR
FLVLEMSARGLGHIASLATIAPPRIGVILNVGTAHLGEFGSRDAIALAKGELAEALPTAA
DGGVAVLNADDPLVAAMASRTSARVVLVGQSEAADIRATDIVLDEKARARFTLTTSSGSV
PVELAVHGEHQVGNALAAAAVAFECGADLGQVAQALSGAAAVSARRMDVRDRPDGVTVVN
DSYNANPDSMRAAIKALVSMAKTGRGAARRSWAVLGEMAELGPESVVEHDAIGRFAVRLD
VSKLIIVGTGRPARAMHQGAVMEGSWGDEAILVPDAASAIALLEEELAAGDLVLVKASQS
IGLWEVADAVLAGHTGQKGSEAMR
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacactcgctcgcatcgcccaaatcgtgggaggcgagctccacgacgtc
gtcgatccctcgaccgaggtgaccggcagcgtggaattcgattcgcggaaggtaggtcca
ggcggcctcttcctcgctctgcccggtgcccgcgtcgacggtcacgaccatgcggcggcc
gccgttgcggcaggtgcgtccgccgtcgtggctgcgcggccggtcggggttccggccgtc
gtggtcccgccgattcccgtggacgtcccgagccgggcgatggcactcgaacacgattcg
gacgggtccggcgccgcggtgctcgccgctctggcgaagcttgcccgcgcctctgtcgac
gaactgaccgacaagggcttgaccgtggtcggagtgaccgggtcagcgggcaagacctcg
accaaagacctcctcgcggctgttctgcgccccctgggccccgtggtggcgccgcctgga
tcgttcaacaacgagctcggccacccgtggactgccctgcgcgctgatgccgacacccgg
ttcctggttctagagatgtctgcgcgcgggctggggcacatcgcgtccctcgcgaccatc
gcgcctccccggatcggggtcattctcaacgtgggcacggcacatctcggtgagttcggg
tcccgggacgcgatcgccctggcgaagggggagctcgccgaagcgctgccgactgccgcg
gacggcggcgtcgccgtgctcaatgcagacgaccctctggtcgccgccatggcctcacgg
acctctgcgcgcgtggtgctcgtcggtcagtcggaggcggcggatatccgggccaccgac
atcgtgctcgacgagaaggcgcgtgcgcgattcacgctcaccacgtcttcgggcagtgtt
ccggtcgagctggcggtgcacggcgaacatcaagtcgggaacgcactcgccgctgccgca
gtggctttcgagtgcggcgcagatctcggccaggttgcccaggcactgtccggggccgct
gcggtgtcggctcgccgtatggatgtgcgagaccggccggacggtgtgacggttgtcaac
gattcgtacaacgccaatcccgattcgatgcgcgcagccatcaaggcgctggtgtcgatg
gcgaagaccggccgcggcgcggcgcgccgcagttgggcggtactcggagaaatggcggag
ctggggccagaatcagtggtcgaacacgatgcgatcggcaggttcgcggtccggctggac
gtgagcaagttgatcatcgtcggaaccggcagaccggcacgggccatgcatcagggcgcg
gtcatggagggctcgtggggcgacgaggcgatactcgttcccgacgccgcctccgcgatc
gcgttgctcgaggaggaattggcggcgggtgacctggtattggtcaaagcgtcgcaatcc
atcggactatgggaggtcgcggacgcggtgctggcgggacacacgggacagaagggttcg
gaggccatgcggtga
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