Rhodococcus sp. 21391: GO592_08850
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Entry
GO592_08850 CDS
T10971
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rhzq Rhodococcus sp. 21391
Pathway
rhzq00300
Lysine biosynthesis
rhzq00550
Peptidoglycan biosynthesis
rhzq01100
Metabolic pathways
rhzq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rhzq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GO592_08850
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GO592_08850
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GO592_08850
Enzymes [BR:
rhzq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GO592_08850
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QQZ16269
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Position
1865294..1866808
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AA seq
504 aa
AA seq
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MIPMTLARVAEIVGGELHDVADPSAEVTGTVEFDSRKVTAGGLFLALPGARVDGHDHAAS
ALEAGAVAVLAARPVGVPAVVVTPTPSDIPSKAMALEHDTDGSGAAVLAALAKLARASVD
DLTAKGLTVVGVTGSAGKTSTKDLLAAVLRPLGPVVAPPGSFNNELGHPWTALRADADTG
YLVLEMSARGRGHIASLATIAPPKIGVVLNVGTAHLGEFGSRDAIAAAKGELAESLPSAD
DGGVAILNADDPLVAAMAPRTSARVVLVGQSESAHVRATDIVLDEKARARFTLTAPAGSV
TVELAVHGEHQVGNALAAAAVALECGADLQQIALALSGAAAVSARRMDVRDRPDGVTVVN
DSYNANPDSMRAALKALVSMARTGRGAARRSWAVLGEMAELGPESVVEHDAIGRFAVRLD
VSRLIIVGTGRPARAMHQGAVMEGSWGEESILVPDIAGAVALLEQELAPGDLVLVKASQS
IGLWEVADTVLAGSTGQKGSEATR
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgatgacactcgctcgcgtcgccgagatcgtgggcggcgaactgcacgacgtc
gccgatccgtcggccgaggtgacgggaacggtcgagttcgactcgcggaaggtcaccgcc
gggggtctgttcctcgccctgcccggcgcccgagtggacggccacgatcacgcggcctcg
gcgctcgaggccggtgcggtcgcggtcctggcggcgcgcccggtcggcgtccccgcggtc
gtcgtcaccccgacaccgagcgacatcccgagcaaggcgatggcactcgagcacgacacc
gacggatcgggcgccgccgtgctcgcggccctcgcgaagctcgcgcgcgcatccgtcgac
gacctcaccgcgaaggggctcaccgtcgtcggcgtcaccggatcggcgggaaagacgtcg
acgaaggatctgctcgccgccgtcctgcgccccctcggccccgtcgtcgcgccgcccgga
tcgttcaacaacgaactcggccacccgtggaccgccctccgcgcggacgcggacacggga
tacctggttctggagatgtcggcccgcggccgcggccacatcgcctccctcgcgacaatc
gcacccccgaagatcggggtcgtcctcaacgtgggcacggcgcacctcggcgaattcggt
tcgcgtgatgcgatcgccgccgccaagggcgaactcgcggagtcgctgccctcggcggac
gacggtggcgtcgcgatcctcaacgcagacgatccgctggtggcagccatggccccgcgc
acgtcggcccgggtggtcctcgtcggccagtcggagtccgcgcacgtgcgggccaccgac
atcgtgctcgacgagaaggcaagggcgcgtttcactctcacggcgccggcgggcagtgtg
accgtcgagctcgccgtgcacggcgaacaccaggtcggcaacgcgctcgccgcagcggcg
gtggcgctcgaatgcggggcggacctccagcagatcgcgctggccctctccggtgccgcc
gccgtctcggcgcgccggatggacgtccgcgaccggccggacggtgtgaccgtcgtcaac
gattcgtacaacgcgaaccccgactcgatgcgggcggccctgaaggcgctggtgtcgatg
gccaggacgggccggggtgcggcgcgccggagttgggcggtgctcggagaaatggccgag
ctgggtccagaatcagtggtcgaacacgacgccatcggcagattcgccgtccggctggac
gtgagcaggctgatcatcgtcggaaccggcaggcccgcccgcgccatgcaccagggtgcg
gtcatggagggttcgtggggcgaggagtcgatcctcgtccccgacatcgccggtgcggtc
gccttgctcgaacaggaactggcgccgggtgatctggtgctggtcaaggcgtcgcagtcc
atcggattgtgggaggttgcggacacggtgttggcgggaagcacgggacagaagggttcg
gaggctacgcggtga
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