Roseburia intestinalis M50/1: ROI_02210
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Entry
ROI_02210 CDS
T02598
Name
(GenBank) Isopropylmalate/homocitrate/citramalate synthases
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
rim
Roseburia intestinalis M50/1
Pathway
rim00290
Valine, leucine and isoleucine biosynthesis
rim00620
Pyruvate metabolism
rim01100
Metabolic pathways
rim01110
Biosynthesis of secondary metabolites
rim01210
2-Oxocarboxylic acid metabolism
rim01230
Biosynthesis of amino acids
Module
rim_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rim00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ROI_02210
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ROI_02210
Enzymes [BR:
rim01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ROI_02210
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
HTH_18
HTH_AraC
HTH_24
WAC_Acf1_DNA_bd
HTH_3
HTH_Tnp_1_2
Motif
Other DBs
NCBI-ProteinID:
CBL07547
LinkDB
All DBs
Position
204382..206382
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AA seq
666 aa
AA seq
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MNFDVAEKYGKAYFMPPEVTYDWVKKDAIEKPPIWCSVDLRDGNQALIEPMNLEEKIEFF
QMLVDIGFKEIEVGFPAASETEYNFMRALIERNMIPEDVTVQVLTQAREHIIKKTFEAVK
GAPHAVIHLYNSTSVAQREQVFKKSREEVKKLAVDGAILLRDLAAQTDGNFTFEYSPESF
PGTEVDYAVEICNAVLDVWKPDKEHKAIINIPTTVQIAMPHVFACQIEYIHKHLKYRDNV
ILSVHPHNDRGCGISDAEFGVLAGADRVEGTLFGNGERTGNVDIVTLAMNMVCHGVDPKL
DFSNIAAIREKYERFTRMRVYERTPYAGDLVFTAFSGSHQDAISKGMAWREAGKSGGRWD
VPYLPIDPKDVGREYESDVIRINSQSGKGGVAFVLKQNFGMSLPDKMKEEVGYLIKGVSD
HRHEELTPDMIYQVFTGNYVNIKDVFDVPDCHFEQKDGIAASVTIEQNGERRVIETSGNG
RLDAVSNAIKMYFGISYELATYQEHAISEGSSSKAAAYVEIICQGRHFWGVGVDEDIIKS
SIAALVSAANKMAKSENIIEGRDERIMEIMNYIQNNYADVTMDVLAEKFGLSKPYLSKYI
KEKSGMTFQDAVKAARMKKARRLLKESNQTVESIAASVGYENVEHFNRLFKKAYEMTPVQ
FRRQYK
NT seq
2001 nt
NT seq
+upstream
nt +downstream
nt
atgaattttgatgttgcagaaaaatacggaaaagcatattttatgccgccggaagttaca
tatgactgggtaaagaaggatgcgatcgaaaaaccgccgatctggtgcagcgtggatctg
cgtgatggcaaccaggcactgatcgagccgatgaacttagaggaaaaaattgaatttttc
cagatgcttgtagacattggattcaaggagatcgaggttggtttcccggcagcttcagag
acagagtacaatttcatgcgtgccttaatcgagcgcaatatgatcccggaagatgttacc
gttcaggttttaacacaggcgcgtgagcacatcattaaaaaaacatttgaggcagtcaaa
ggcgcaccgcacgcagtgatccatctttacaactccacctctgttgcacagagagagcag
gtctttaaaaagagcagggaagaagtaaagaaacttgcagtggatggagcgattctgtta
agagatcttgcagcacagacagatggaaactttacatttgagtacagcccggagagcttc
cctggaacagaggtcgactatgccgtggaaatctgcaacgccgtactggatgtgtggaaa
ccggataaggaacacaaagcgatcatcaacattccgactacggttcagattgcaatgccg
catgtatttgcatgccagatcgagtatattcacaaacatttaaaatacagagataacgtg
atcttaagcgtacatccgcacaacgacagaggctgcggtatcagtgatgctgagtttggt
gtattagcgggagctgaccgtgtggaaggtactctgtttggaaatggagagcgtaccgga
aacgtggatatcgtgacacttgcaatgaatatggtatgccacggcgtagatccgaaactt
gatttctccaacattgcagcaatccgtgagaaatatgagcgttttaccagaatgagagtt
tatgagcgtactccgtatgccggagatcttgtgtttactgcattttccggttcccatcag
gatgcgatctcaaaaggcatggcatggagagaggcaggaaagagcggcgggcgctgggat
gttccgtatctgccgatcgatccgaaggatgtcggaagagagtacgaatccgatgtgatc
cgaatcaacagccagtccggtaagggaggagttgctttcgtattaaaacagaactttggc
atgtccctgccggataagatgaaagaggaagtcggttatctgatcaaaggtgtatccgat
cacagacacgaagagctgacaccggatatgatctatcaggtatttaccgggaattacgtc
aatatcaaagatgtatttgatgtgccggattgccatttcgagcagaaagacggcattgcc
gcaagtgtgacgatcgagcagaacggtgagcgcagagtgatcgagacaagcggaaacgga
cgcctcgatgcggtcagcaacgcaatcaagatgtattttggcatcagctatgagctggca
acttaccaggagcatgcaatctcagagggatcttcctcaaaagcagcggcttatgtggag
atcatctgtcagggcagacatttctggggcgtcggcgtggatgaggatatcatcaagagt
tccatcgcagcactggtttctgctgcaaataagatggcaaaaagcgaaaacatcattgag
ggcagagatgaacgcatcatggagatcatgaattacatccagaataactatgcggatgtg
acgatggatgtcctggcagaaaaatttggactttccaaaccgtatctttccaaatatatc
aaggaaaaatccggtatgacattccaggatgcagtgaaggctgcgcggatgaaaaaagcg
agaagactgttaaaagagtcaaatcagacggtggagtcgattgcagcgagtgtgggatat
gagaacgtggagcattttaaccgcctgttcaaaaaggcgtatgagatgacaccggtacag
ttccgcagacagtataaataa
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