Roseburia intestinalis M50/1: ROI_16740
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Entry
ROI_16740 CDS
T02598
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rim
Roseburia intestinalis M50/1
Pathway
rim00300
Lysine biosynthesis
rim00550
Peptidoglycan biosynthesis
rim01100
Metabolic pathways
rim01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rim00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ROI_16740
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ROI_16740
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ROI_16740
Enzymes [BR:
rim01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ROI_16740
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
CBL08776
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All DBs
Position
1678739..1680151
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AA seq
470 aa
AA seq
DB search
MKNMTLERITEVCGGVYYGSEADKKKEIAGAVIDSRQVESGYLFIAVKGEKVDGHQFIPQ
VFEKGALAVLSEQELSDPAGPYIRVESTLGAMKKLAAYYRRSLDIKVVGITGSVGKTSTK
EMIASVLSQKYNVLKTEGNFNNEIGLPLTIFKIREQHEVAVLEMGISEFGEMHRLAEMAY
PDICVITNIGLCHLENLLTRDGILKAKTESFEHLTPEGTAVLNGDDDKLCEKKMVNGKPV
VFYGIGKEAKPAKTEQGEKYLAEKEVYATDVEPVGLDGTKAVIHIGAESFAVTIPIAGEH
NVYNALAAVCVAGKLGLSVDEMKRGIESVKTIGGRSNLIHKGGMTIIDDCYNANPVSMKA
SIDVLAAAPGRKIAVLGDMGELGENEQELHAMVGEHFEGKGIDALFAAGALSENLAQAVG
KCSKETEVHYFKTKDELMEELLPYVKSGDTVLVKASHFMGFPEVVGQLTK
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaacatgacactggagcgtattacggaagtatgcggtggagtatattatggcagt
gaggccgacaaaaagaaagaaattgcaggagctgtgatcgacagcagacaggtagagtca
ggatatctttttattgcggtaaagggagaaaaggtggatggtcatcagttcattccacag
gtgtttgaaaaaggtgcacttgccgtattatctgaacaggaactgtcagatccggcgggc
ccttatatcagggtggaatctacacttggtgcaatgaaaaaacttgcggcatactaccgc
agaagtcttgatattaaggtcgtcggaattaccggaagtgtcggaaaaacaagcacaaag
gagatgattgcgtcggttctttcacagaagtataatgtgttaaagacagagggcaatttc
aataacgagatcggtcttccacttacgatttttaagatcagggagcagcatgaagtggca
gtgcttgagatgggaatttcagaattcggtgagatgcaccgtctggctgaaatggcatat
ccggatatctgtgtgatcacaaatatcggattgtgccatctggaaaacctgctgaccaga
gatggaattttaaaggcaaaaacggagagttttgagcacctgacaccggaaggaactgcc
gtgttaaatggagatgatgataagctctgtgagaaaaagatggtgaacggaaaaccggtg
gtattttatggtatcggaaaagaagcaaagcctgcaaagacagagcagggtgaaaaatat
cttgccgaaaaggaagtatatgcaacagatgtggaaccggtaggattagatggaacaaaa
gcggtgatacatattggtgcagagagctttgcagtgacgatcccgattgcaggagagcat
aatgtatacaatgctttagccgcagtctgcgttgcaggaaagcttggacttagtgtggat
gaaatgaaacgcgggattgagtcggtaaaaacgatcggaggaagaagtaatctgatccac
aaaggcgggatgacgatcatcgatgactgttacaacgcaaaccctgtttccatgaaggcg
tccatcgacgtgctcgcagcggcacctggaagaaaaatcgcagtgcttggagatatggga
gaacttggcgaaaatgagcaggaactgcatgccatggtcggagaacatttcgaaggaaaa
ggaatcgatgctttgtttgcagccggtgcattatcagagaatctggcacaggcagtagga
aaatgcagtaaggagacggaggttcattatttcaaaacaaaagatgaactgatggaagaa
ttactgccttatgtaaaaagcggtgacacggttctggtaaaggcatcccactttatggga
ttcccggaggtcgtaggacagcttacaaagtaa
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