Roseburia intestinalis M50/1: ROI_38830
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Entry
ROI_38830 CDS
T02598
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
rim
Roseburia intestinalis M50/1
Pathway
rim00230
Purine metabolism
rim01100
Metabolic pathways
rim01110
Biosynthesis of secondary metabolites
Module
rim_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
rim00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ROI_38830
Enzymes [BR:
rim01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ROI_38830
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
CBL10639
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Position
3890152..3893955
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AA seq
1267 aa
AA seq
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MSSVKRVYVEKKPEYAVRAKELQSEIRSYLGISGVTKVRELIRYDIENISGETYKKALVT
VFSEPPVDDIYEEEFDLNGARTFSVEFLPGQFDQRADSAEQCVKLLNEEEEPIIRTAVTY
AIEGTISDEEFAAIKKHCINPVDSRETGLEKPETLVQSFPEPEDVKIFDGFRDTPEAKLK
ELYDSLNLAMTFKDFLHIQNYFKNDEKRDPSMTEIRVLDTYWSDHCRHTTFSTELKNVAF
DDGYYCAPMKETYEDYLNTHKNLYAGRSDKFVCLMDLALMAMKRLKKEGKLQDQEESDEI
NACSIVVPVEVDGKTEEWLVNFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRTYVYQA
MRVTGAADPTVPVSETISGKLPQKKLVREAAHGYSSYGNQIGLATGYVKEVYHPNYVAKR
MEIGAVMGAAPRRAVQRLTSDPGDIIILLGGRTGRDGIGGATGSSKAHNTESTAVCGAEV
QKGNPPTERKIQRLFRREEVAHIIKKCNDFGAGGVSVAIGELADGLRVQLDKVPKKYAGL
DGTELAISESQERMAVVVSPSDVKTFLGYAAEENLEAVEVAVVTEEPRLVLEWRGKEIVN
ISRAFLDTNGAHQETNVAVDMPVPEDNYLNKISTPKVADAVAKNDMKAAWLAELADLNVC
SQKGLVEMFDGSIGAGSVFMPFGGKYQLTETQSMVAKLPVAHGKCDTVTMMAYGFDPYLA
SWSPYHGAIYAVLESLSRIVTAGGDYKKIRFTFQEYFRRMNEDPKRWSQPFAALLGAYNA
QIGFGLPSIGGKDSMSGTFNDIDVPPTLVSFAVDVAKEQDIITPELKAAGNELLYFTIDK
DEYDVPVYAQVMKLYDAVHVLIQKGAIVSAYALDGKGLAAALAKMAFGNKLGVTVDTDVT
TDTLFAPGFGNIVAEVPAGKTAEVYEALQNAGLSANVKRAGAVNEEAAFICGDMKLAIDE
ALNAWTGTLEKVFPTRATEDKEEVKTDLYHADSVYVCKHKVARPTVFIPVFPGTNCEYDS
AKAFERAGADTIVKVFKNLNAEDIRESVDEFTKAIDQAQIIMFPGGFSAGDEPEGSAKFF
ATAFRNAKMTEAVMKLLNERDGLALGICNGFQALIKLGLVPYGEIRPQAADSPTLTYNTI
GRHISKMVYTKVVTDKSPWLAQAELGKVYCNPASHGEGRFVAPKEWLDKLFANGQVATQY
VNEAGVPTMDEEWNVNGSYCSIEGITSPDGRVLGKMAHSERRDRSVAMNIYGEQDLKIFE
SGVAYFK
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
atgagcagtgtaaaacgtgtatatgttgagaagaaaccggaatatgcagtccgggcaaaa
gaattgcagtctgaaatcagaagttatcttggaatcagtggtgtgacgaaggtacgcgag
ctgatccgttatgatattgaaaatatttccggggaaacttataaaaaagccttagtaacc
gttttttccgaaccgccggtagacgatatttatgaggaagagtttgatttaaacggagca
agaacattttccgtagagttcttaccgggacagtttgaccagagagcagattctgcagaa
cagtgcgtgaaattattaaatgaagaggaagagccgatcatccgcactgcagtgacttat
gcgatcgagggaacgatcagtgacgaagaatttgcagcgatcaaaaaacactgcatcaac
ccggtcgattccagagagacaggcttagagaaacctgagactttagtgcagagtttcccg
gagccggaggatgttaagatctttgacggttttcgtgatacgccggaggctaagttaaaa
gagttatacgattcattgaatcttgcgatgacattcaaagactttttacatatccaaaat
tattttaagaacgatgaaaaacgcgatccgtccatgacggagatccgtgtgttagatacc
tactggtctgatcactgccgtcataccacattctccacagaacttaaaaatgtggcattt
gatgacggttattactgcgcgccgatgaaagagacttatgaggattacttaaatacccac
aagaacctgtatgcaggacgcagcgataagtttgtatgtctgatggatcttgccctgatg
gcaatgaaacgtctgaaaaaagaaggaaagttacaggatcaggaagagtccgatgagatc
aatgcatgttccatcgttgttccggtagaagtagacggaaagacagaggagtggctggtt
aatttcaaaaatgaaacacacaaccatccgaccgagatcgagccgtttggtggtgccgct
acctgtcttggcggtgcgatccgtgacccgttgtcaggacgtacctatgtttaccaggca
atgcgtgtgaccggtgccgcagatccgacggttcctgtttccgagacgatctccggaaaa
cttccgcagaaaaaactggtgagagaagcagcacacggatacagctcttacggtaaccag
atcggtcttgcaaccggatacgtcaaagaagtttaccatccaaactatgtggcaaaacgt
atggagatcggtgcggtcatgggtgctgctccaagacgtgccgtacagagactgacctct
gatccgggtgacatcatcattttacttggaggaagaaccggacgtgacggtatcggtggt
gccacaggttcttcaaaagcgcacaacacagagtccacagcagtctgcggtgccgaggta
cagaaaggtaacccgccgacagaacgcaagatccagcgcctgttccgccgtgaggaagtt
gcccatatcatcaaaaaatgcaacgatttcggtgcgggcggtgtgtctgtagcaatcggt
gagcttgcagacggacttcgcgtacagcttgacaaagtgccgaagaaatatgccggatta
gacggaacagaacttgcaatctcagaatcccaggagcgtatggcagttgtggtatctcct
tcggatgtcaagactttcttaggctacgcagcggaggaaaacttagaggcagtggaagtt
gccgttgtaacggaggagccgagacttgttttagagtggagaggcaaagagatcgtaaat
atctcccgtgccttcttagacaccaacggtgcgcatcaggagaccaacgttgcagtggat
atgccggtaccggaggataattacttaaataagatctctacaccaaaagttgcagatgcg
gttgcgaaaaacgatatgaaggcagcatggcttgcagagctggctgatttgaatgtctgc
tcccagaaaggtcttgtggagatgtttgacggttccatcggagcaggaagcgttttcatg
ccatttggtggaaaatatcagctcacagaaacacagtccatggtggcaaaacttccggtt
gcacatggaaaatgtgataccgtaaccatgatggcatatggttttgatccgtatttagca
agctggagcccgtaccacggtgcgatctatgcggtattagagtccttatcaagaatcgtg
accgcaggtggtgattataaaaagatccgttttacattccaggaatacttccgcagaatg
aacgaggatccgaagcgctggagccagccatttgcagcacttctcggagcttacaatgca
cagatcggttttggacttccatctatcggtggaaaagattccatgtcaggaacgtttaat
gatattgatgtaccgccgacactggtttcctttgcagtggatgtggcaaaagagcaggat
atcatcacaccggagttaaaggcagcaggaaatgaactgttatactttacaatcgacaaa
gacgaatatgacgtgccggtttacgcacaggtcatgaaactttatgatgcggttcatgta
ttgatccagaaaggtgcgatcgtttccgcatatgcgcttgacggaaaaggtcttgcagca
gcacttgcaaagatggcattcggtaacaaacttggcgtgacagtagataccgatgtgaca
actgatacactgtttgctccgggctttggtaatatcgtggcagaagttccggcaggcaag
actgcagaagtttacgaggcactgcagaatgcaggtttatctgcaaacgtaaagagagca
ggtgctgtcaatgaggaagcagcatttatctgtggcgatatgaaacttgcgatcgatgag
gcattgaacgcatggacaggcacattggagaaagtattcccgactcgtgcaaccgaagat
aaagaggaagtaaagacagatctttatcatgcagattctgtttatgtatgcaaacataaa
gtggcaagaccgaccgtatttattccggtattcccgggaaccaactgcgagtacgacagt
gcaaaagcgtttgagcgcgcaggtgcggatacgatcgtaaaagtatttaaaaacttaaat
gctgaggacatccgtgagtccgtagatgaatttaccaaggcaatcgaccaggcacagatc
atcatgttcccgggtggattctccgccggtgatgagccggaaggatctgcaaaattcttt
gcaaccgcattccgcaacgcaaagatgacagaggcagttatgaaactgttaaatgagaga
gacggtttagcccttggtatctgtaacggattccaggcactgatcaaattaggactggta
ccttacggcgagatccgcccgcaggcagcagattccccgacactgacctacaacacgatc
ggacgccatatcagcaagatggtatacacaaaagttgtcaccgacaagtccccgtggtta
gcacaggcggaacttggaaaagtttactgcaacccggcatcccacggagagggacgcttt
gttgcaccgaaagaatggcttgataaactgtttgcaaacggtcaggttgcaacacagtac
gtcaatgaggcaggtgttccgaccatggacgaagagtggaacgtcaatggttcctactgt
tccatcgagggtatcacaagcccggatggacgtgtgctcggcaagatggctcattccgag
agacgtgacagaagcgtggcaatgaacatttacggagaacaggatctgaagatctttgag
tccggtgtggcttattttaaataa
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