Roseburia intestinalis XB6B4: RO1_42230
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Entry
RO1_42230 CDS
T02597
Name
(GenBank) Isopropylmalate/homocitrate/citramalate synthases
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
rix
Roseburia intestinalis XB6B4
Pathway
rix00290
Valine, leucine and isoleucine biosynthesis
rix00620
Pyruvate metabolism
rix01100
Metabolic pathways
rix01110
Biosynthesis of secondary metabolites
rix01210
2-Oxocarboxylic acid metabolism
rix01230
Biosynthesis of amino acids
Module
rix_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rix00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
RO1_42230
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
RO1_42230
Enzymes [BR:
rix01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
RO1_42230
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
HTH_18
HTH_AraC
HTH_24
WAC_Acf1_DNA_bd
HTH_3
HTH_Tnp_1_2
Motif
Other DBs
NCBI-ProteinID:
CBL14385
UniProt:
D4L445
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All DBs
Position
4174016..4176022
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AA seq
668 aa
AA seq
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MNMNFDVAEKYGKAYFMPPEVTYDWVKKDAIEKPPIWCSVDLRDGNQALIEPMSLEEKIE
FFQMLVDIGFKEIEVGFPAASETEYNFMRALIERNMIPEDVTVQVLTQAREHIIKKTFEA
VKGAPHAVIHLYNSTSVAQREQVFKKSREEVKKLAVDGAILLRDLAAQTDGNFTFEYSPE
SFPGTEVDYAVEVCNAVLDVWKPDKEHKAIINIPTTVQIAMPHVFACQIEYIHKHLKYRD
NVILSVHPHNDRGCGISDAEFGVLAGADRVEGTLFGNGERTGNVDIVTLAMNMVCHGVDP
KLDFSNIAAIREKYERFTRMRVYERTPYAGDLVFTAFSGSHQDAISKGMAWREAGKSGGR
WDVPYLPIDPKDVGREYESDVIRINSQSGKGGVAFVLKQNFGMSLPDKMKEEVGYLIKGV
SDHRHEELTPDMIYQVFTGNYVNIKDVFDVAECYFEQKDGIAASVTIEQNGERRVIETSG
NGRLDAVSNAIKMYFGISYELATYQEHAISEGSSSKAAAYVEIICQGRHFWGVGVDEDII
KSSIAALVSAANKMAKSENIIEGRDERIMEIMNYIQNNYADVTMDVLAEKFGLSKPYLSK
YIKEKSGMTFQDAVKAARMKKARRLLKESNQTVESIAASVGYENVEHFNRLFKKAYEMTP
VQFRRQYK
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atgaatatgaattttgatgttgcagaaaaatacggaaaagcatattttatgccgccggaa
gttacatatgactgggtaaagaaggatgcgatcgaaaagccgccgatctggtgcagcgtg
gatctgcgtgatggcaaccaggcactgatcgagccgatgagcttagaggaaaaaattgaa
tttttccagatgcttgtagacattggattcaaggagatcgaggttggtttcccggcagct
tcagagacagagtacaatttcatgcgtgccttaatcgagcgcaatatgatcccggaagat
gttaccgttcaggttttaacacaggcgcgtgagcacatcattaaaaaaacatttgaggca
gtcaaaggcgcaccgcacgcagtgatccatctttacaactccacctctgttgcacagaga
gagcaggtctttaaaaagagcagggaagaagtaaagaaacttgcagtggatggagcgatt
ctgttaagagatcttgcagcacagacagatggaaactttacatttgagtacagcccggag
agcttccctggaacagaggtcgactatgccgtggaagtctgcaacgccgtactggatgtg
tggaaaccggataaggaacacaaagcgattatcaacattccgactacggttcagattgca
atgccgcatgtatttgcatgccagatcgagtatattcacaaacatttaaaatacagagat
aacgtgatcttaagcgtacatccgcacaacgacagaggctgcggtatcagtgatgctgag
tttggtgtattagcgggagctgaccgtgtggaaggtactctgtttggaaatggagagcgt
accggaaacgtggatatcgtgacacttgcaatgaatatggtatgccacggcgtagatccg
aaacttgatttctccaacattgcagcaatccgtgagaaatatgagcgttttaccagaatg
agagtttatgagcgtactccgtatgccggagatcttgtgtttactgcattttccggttcc
catcaggatgcgatctcaaaaggcatggcatggagagaggcaggaaagagcggcgggcgc
tgggatgttccgtatctgccgatcgatccgaaggatgtcggaagagagtacgaatccgat
gtgatccgaatcaacagccagtccggtaagggaggagttgctttcgtattaaaacagaac
tttggcatgtccctgccggataagatgaaagaggaagtcggttatctgatcaaaggtgta
tccgatcacagacacgaagagctgacaccggatatgatctatcaggtatttaccgggaat
tacgtcaatatcaaagatgtatttgatgtggcggagtgctatttcgagcagaaagacggc
attgccgcaagtgtgacgatcgagcagaacggtgagcgcagagtgatcgagacaagcgga
aacggacgcctcgatgcggtcagcaacgcaatcaagatgtattttggcatcagctatgag
ctggcaacctaccaggagcatgcaatctcagagggatcttcctcaaaagcagcggcttat
gtggagatcatctgtcagggcagacatttctggggcgtcggcgtggatgaggatatcatc
aagagttccatcgcagcactggtttctgctgcaaataagatggcaaaaagcgaaaacatc
attgagggcagagatgaacgcatcatggagatcatgaattacatccagaataactatgcg
gatgtgacgatggatgtcctggcagaaaaatttggactttccaaaccgtatctttccaaa
tatatcaaggaaaaatccggtatgacattccaggatgcagtgaaggctgcgcggatgaaa
aaagcgagaagactgttaaaagagtcaaatcagacggtggagtcgattgcagcgagtgtg
ggatatgagaacgtggagcattttaaccgcctgttcaaaaaggcgtatgagatgacaccg
gtacagttccgcagacagtataaataa
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