KEGG   Rhinichthys klamathensis goyatoka (western speckled dace): 130080463
Entry
130080463         CDS       T09701                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
rkg  Rhinichthys klamathensis goyatoka (western speckled dace)
Pathway
rkg04010  MAPK signaling pathway
rkg04012  ErbB signaling pathway
rkg04020  Calcium signaling pathway
rkg04510  Focal adhesion
rkg04520  Adherens junction
rkg04530  Tight junction
Brite
KEGG Orthology (KO) [BR:rkg00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    130080463 (erbb2)
   04012 ErbB signaling pathway
    130080463 (erbb2)
   04020 Calcium signaling pathway
    130080463 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    130080463 (erbb2)
   04520 Adherens junction
    130080463 (erbb2)
   04530 Tight junction
    130080463 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rkg01001]
    130080463 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rkg04147]
    130080463 (erbb2)
   04090 CD molecules [BR:rkg04090]
    130080463 (erbb2)
Enzymes [BR:rkg01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     130080463 (erbb2)
Protein kinases [BR:rkg01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   130080463 (erbb2)
Exosome [BR:rkg04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   130080463 (erbb2)
CD molecules [BR:rkg04090]
 Proteins
  130080463 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Haspin_kinase Kinase-like FixQ
Other DBs
NCBI-GeneID: 130080463
NCBI-ProteinID: XP_056101787
LinkDB
Position
Unknown
AA seq 1278 aa
MEADGSFGLVWVLLLLLGITDAIGREVCLGTDMKLALPSSLENHYEMLRLLYTGCQVVHG
NLEITHLQGTPDLSFLQEIVEVQGYVLIAHVSVRSVPLDNLRIIRGSQLYNSSYALAVHN
NINQSQVGLGLRELRLRSLTEILLGGVYIWGNPQLCFPRNINWKDTVTTLENKLLYLQDI
PKNCPLCSSACSGSGGCWGETNQDCQTLTSVQCSSGCWRCKGPNPNDCCHVQCAAGCTGP
KDSDCLACRHFNDSGTCKDNCPPPTIYDPTSFQSKPNKDKKFSFGATCVKQCPHNYLAME
VACTMVCPKSNKEVITVDPDGQESQKCERCEGECPKVCYGLGMGSLQGVTVVDTTNIGMF
IGCEKIYGSLAFLSDSFKANAVTNSSGLQLSDLEKLKSIKEITGYLYIDAWPDYLLNLSV
FENLKVIRGRMLYKGVLSLGVQSLQIESLGLRSLRSVTGGLVLFHNNSRLCYTSSLPWSP
MLHPTQAPNLISSNNQDPQTCVSEGRICDPLCADAGCWGPGPSQCVSCANYKRGTECVEQ
CNVLQGSFREFVDGFNCDPCHPECQPVNGSASCTGRGPDQCKECMHFQDGDVCVERCPSG
VKEDQHTVWKYFNATRHCLPCETNCSVSCPLDDRGCPIQQKAGPGTTVAITIGGVFLFII
LLALLVFYLRRQKHQKKKEIMRRILQEHELVEPLTPSGAMPNQAQMRILKETELKKLRVL
GSGAFGTVYKGIWAPDGENVRIPVAIKVLRENTSPKANKEILDEAYVMAGVASPHVCRLL
GICLTSTVQLVTQLMPYGCLLDYVKENKDRIGSQYLLTWCVQIAKGMSYLEEVRLVHRDL
AARNVLVKNPNHVKITDFGLARLLDIDEKEYHADGGKVPIKWMALESILHRKFTHQSDVW
SYGVTVWELMTFGMKPYDLIPARDIPELLEGGDRLPQPFICTTDVYMIMVNCWMIDPDSR
PRFKDLVEEFTIMSRDPSRFVVIQNDDQMSLSNPVDSEFFRMLMAEEGGNVKELLDAEEY
LVPQPGGIFSSQGEMRANGPSRHHSHRSTDQGLEVDGMPSGRDLYSSVSTLGQSQYPTLP
VGATANAMWSGTQYPTLVRSISHLSAGGQSDSVFLDGYVEDNGPPSSPGRYSKDPTVPNG
IDGELETWRADGPIGFLSNTLPRGAHTQPEYVNQDVPSERPSTLPRKASERRFINGLCTG
NSVENPEYLVPLGSISPTSPAFDNPYYHDLAAKAQAVARASINGGTNHRQPNGYMTPTAE
NPEYLGLAETWSGQMEYT
NT seq 3837 nt   +upstreamnt  +downstreamnt
atggaggcggacggaagttttgggctcgtctgggtcctgttgctgctgttgggaattaca
gacgctatagggagagaagtatgtcttgggacagatatgaagctggctttaccctccagt
cttgagaatcattatgagatgctcaggctgctgtacacgggctgtcaagttgttcatggt
aacctggagatcacgcatctgcagggaactccagacctctcctttttgcaggagattgtg
gaggttcaggggtatgtgctgatagctcacgtctcggtgcgttcagttcctctggacaat
ctgcggatcatacgaggcagtcagctgtataactccagctacgctctcgcagtgcataac
aacatcaaccagagtcaggtgggactcggcctgagagaactgcgcctcaggagtcttaca
gaaatcctgctcggcggggtttatatttggggaaatcctcaactttgctttccccggaat
attaattggaaagacactgttacaacacttgaaaacaagctgctgtacctgcaagacatt
ccaaagaactgtcctctttgttcttctgcttgttctggatccggtggatgttggggagaa
acaaatcaggactgccaaacattgacctctgtgcaatgctcatctggctgttggcgctgt
aagggtccgaatcccaatgattgctgtcatgtgcagtgtgctgctgggtgcacggggccg
aaagactctgattgtctggcctgccgtcactttaatgacagtgggacgtgtaaagacaac
tgtcccccgcccaccatctacgacccaacctccttccaatccaaacctaacaaggacaaa
aagttcagctttggagccacatgtgttaaacagtgtccccataactatttggccatggaa
gtggcatgtacaatggtctgtcctaaatctaacaaggaagtcatcactgtcgacccagat
ggacaagaatcacagaaatgtgaaaggtgtgaaggagagtgtccaaaagtgtgttatggg
ctaggaatgggaagccttcagggggtgacagtggtggataccaccaacattggcatgttc
attggctgtgagaagatctacggcagtttggcttttctttcagactccttcaaagctaat
gcagttaccaattcatctggactgcagttgagtgacctcgagaagttgaagtcgattaaa
gaaatcacaggatatctgtacatagatgcatggccagattatttgcttaatctgagtgtt
tttgaaaacttgaaggtgatcagaggaagaatgctttacaagggtgttttgtctttggga
gttcagtctttgcagatcgagtctctcgggttgcgttccttgcgcagtgtcaccggaggt
ttagtactgtttcataataactccagactgtgctacacctcctctttgccctggtcccct
atgctccaccccacacaggcacccaacctcatcagcagcaacaaccaagacccgcaaaca
tgtgtttcagagggaagaatctgtgaccctctgtgtgcggatgcaggctgctgggggccg
ggaccaagtcagtgtgtgtcgtgtgcgaattacaaacgtgggacggagtgtgtggagcag
tgtaatgtcctgcagggatcattccgggagtttgtggatggatttaactgtgatccttgc
catccagagtgtcaaccagtcaacggctctgcctcctgtacaggccgaggtccagatcag
tgtaaggagtgtatgcactttcaagatggagacgtgtgtgttgagcgctgtcccagtggg
gtgaaagaggaccagcacacagtgtggaaatacttcaatgctacgagacactgtctgccc
tgtgagaccaactgcagcgtctcgtgtccattggatgatagggggtgcccgatccaacag
aaagctgggcctgggacaacagttgcaatcacaattggtggagtgtttctctttatcatt
ttgctggcgctgctggtgttttacctgcgacgacagaaacaccagaaaaagaaagaaatc
atgaggagaattctacaggaacatgagctggtggagccactgactccgagcggagcaatg
ccgaaccaggctcagatgcgtattctcaaggagacagagctgaagaaactccgagtgctg
ggctctggagccttcggcacagtctataagggtatatgggctcctgatggggaaaacgtc
aggatcccagtggccatcaaagttttgcgtgagaacacctcgcccaaagccaacaaagaa
atcttggatgaggcttatgtgatggcgggtgtagcgagcccacatgtgtgccgcttgcta
ggcatctgtctgacatcaacggttcagctggttactcagctcatgccatacggatgcttg
ttggactatgttaaagaaaacaaggaccgaatcggctctcagtacctcctcacctggtgt
gtacagattgcgaagggaatgagttaccttgaagaagtgaggctggttcacagagacctt
gctgctaggaatgttctagtcaaaaacccaaaccatgtgaagattacagactttgggctt
gccagactgctggacatagatgagaaggagtaccacgctgatgggggaaaggtgccaatc
aaatggatggcgctggagtccatattacacagaaagtttactcaccaaagtgatgtatgg
agctacggggtgactgtgtgggagttgatgacctttggcatgaagccatatgacctcata
ccagcgcgggacattccagaactactggaggggggagacagactcccccagccgtttatc
tgtaccacggacgtctacatgatcatggtcaattgttggatgatcgatcctgacagtcga
ccgcgatttaaggacctggtggaggaatttaccatcatgtcacgtgatccctcacgtttt
gtcgtcatccaaaatgacgatcagatgagtctgtcgaatcctgttgatagtgagttcttc
cgcatgttgatggctgaggagggggggaatgtgaaggagttactggatgcggaagaatac
ctggtgcctcagcccggcggcatcttcagctcgcaaggagaaatgagagccaatggaccc
agcagacaccactctcatcggagtacagaccaaggtttagaggtggatggtatgccaagc
gggagggatttgtactcctccgtcagcacgctggggcagagtcagtacccaactcttcct
gtcggggcaacagccaatgccatgtggtctgggacacagtacccaactttagtacggagc
atatcacacctttccgctggaggccaatcggactctgtgtttctggacggttacgtggag
gacaacggccctccatccagtcctggtcgttattctaaagaccccaccgtccccaacggc
atagatggagagctggagacctggagagcggatggccctattggcttcctttcaaacaca
ctgccacgtggagcgcacacacaacctgagtatgtgaaccaggacgtcccatcagagcgt
cccagcacgcttccacgcaaagcgagcgagaggagattcattaacggtctttgtacaggg
aacagtgtggagaatccagagtacctggtgcctttgggcagcatctcacccacctctcct
gccttcgacaacccctactatcatgatctcgcagctaaagctcaggcagtcgccagagcg
tccataaacggaggtacgaatcacaggcagcccaatggctacatgacccccacagcagaa
aacccagaatacctgggcttagcagagacatggagtggtcaaatggagtatacttga

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