Ruminococcus lactaris: NQ541_00360
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Entry
NQ541_00360 CDS
T08757
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rlr
Ruminococcus lactaris
Pathway
rlr00300
Lysine biosynthesis
rlr00550
Peptidoglycan biosynthesis
rlr01100
Metabolic pathways
rlr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rlr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NQ541_00360
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NQ541_00360
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NQ541_00360
Enzymes [BR:
rlr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NQ541_00360
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
RhaT
Motif
Other DBs
NCBI-ProteinID:
UWP65633
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Position
complement(62717..64108)
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AA seq
463 aa
AA seq
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MKNMSLKEIAAACGGTYHGDPALLSKEASSVAIDSRKVQKDTLFVAIKGARVDGHSFIPQ
VMDQGAICSLSEQDLGDVTYPYIQVASCTEALKDLAEHYRRSLDIKVVGISGSVGKTSTK
EMIASVLSEKYCVLKTEGNFNNEIGLPLTVFNLRKEHEVAVLEMGISHFGDMEPLAKIAR
PDVCVITNIGYAHLENLGTRDGILKEKTSMFDFMNPDGTVILNGDDDKLRGYTSERGIQP
VYFGLDPACPFHAEQIQKMGLKGTVATFVTPSSSFSAHVSIPGDHMISNALAGVAVGYAL
GMKDEEIIRGIEKLVPIAGRNNLIEAEHYTIIDDCYNANPASMKSSLDVLAFADTRTVAI
LGDMGELGADEKKMHAEVGSYAVKKGISLLICIGTLSAEMANAARTASEASSDSDTKTLV
YHFDTKEAFYRQMDQLLKEQDTVLVKASHFMEFPEIVKRLQVQ
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaatatgagcttaaaggaaatagctgctgcctgtggcggcacataccacggtgat
cctgcccttctttcaaaagaggcatccagcgtcgctatcgacagccgtaaggtccagaaa
gatacgctctttgtagcaattaagggtgccagagtggatggccacagctttatccctcag
gtcatggaccagggtgccatctgctctttatctgaacaggatcttggagatgtaacttac
ccttatatccaggttgcatcctgcacagaggctctcaaggatcttgcagaacattaccgt
cgttcactggacatcaaagtggtaggaatctccggcagcgttggaaagaccagtaccaaa
gaaatgatcgcatccgttctttctgaaaagtactgtgtattaaagaccgaagggaatttc
aacaacgagatcggacttcctctgaccgtattcaatctccgcaaggagcatgaagttgct
gttcttgaaatggggatcagtcatttcggtgatatggaaccacttgcaaagattgcacgc
ccggatgtctgcgtgatcacaaatatcggatatgctcatctcgaaaatctcggaacaagg
gatggtattttaaaagaaaagacttccatgttcgatttcatgaatcctgatggtactgtc
attctcaacggtgatgatgacaagctccgtggatatacttccgaacgtgggattcagccg
gtttacttcggactcgatcctgcctgcccgttccacgcagaacagattcagaaaatggga
ctgaaaggaacagttgccacattcgtgacaccttcttccagtttttccgcccacgtttcc
atccccggagatcacatgatctccaatgcacttgcaggagttgccgtcggttatgcactt
ggaatgaaagacgaagagatcatccgtggaattgaaaagcttgtcccgatcgcaggacgc
aacaatctgatcgaggcagaacattatacaatcattgatgactgttataatgccaatccg
gcttctatgaagtcctctcttgatgttctcgcctttgccgatacccgcaccgtagcaatc
ctcggtgatatgggagaacttggagcagatgaaaagaaaatgcatgccgaagtgggaagt
tatgccgttaaaaagggcatcagccttctcatctgcatcggaactctttccgcagaaatg
gcgaatgccgcccggacagcttctgaagcatcttctgattccgacaccaaaactctcgta
tatcattttgatacaaaagaagctttttaccggcagatggatcagcttttaaaagaacag
gatactgttctcgtcaaggcatctcattttatggaatttcctgaaattgtgaagaggctg
caagtacaataa
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