Ruminococcus lactaris: NQ541_04500
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Entry
NQ541_04500 CDS
T08757
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
rlr
Ruminococcus lactaris
Pathway
rlr00230
Purine metabolism
rlr01100
Metabolic pathways
rlr01110
Biosynthesis of secondary metabolites
Module
rlr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
rlr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NQ541_04500
Enzymes [BR:
rlr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NQ541_04500
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
NapD
Motif
Other DBs
NCBI-ProteinID:
UWP66367
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Position
977081..980836
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AA seq
1251 aa
AA seq
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MSNVKRVYVEKKPEFAVTAKGLGHEIRHYLGIKDVTGVRVLIRYDAENISDETFEKACGG
VFAEPPVDILYRESFTKNETDRCFSVEFLPGQFDQRADSAEQCIRFIKEDETPVIRTAVT
YVIEGNISEEEFEAIKNHCINPVDSREAAAEKPKTLVTVFEEPADVKVFDGFKDMPEAEL
KELYDSLGLAMTFKDFQHIQKYYHGEEDRNPTMTEIRVLDTYWSDHCRHTTFSTELKDVK
FDDGDYRDAIEDTYKEYLKDHSEIFKGREDKFVCLMDLALMAMRRLKKEGKLADQEESDE
INACSIVVPIKVDGVEEEWLINFKNETHNHPTEIEPFGGAATCLGGAIRDPLSGRTYVYQ
AMRVTGAADPTVSANETLKGKLPQKKLVREAAHGYSSYGNQIGLATGLVKEIYHPDYVAK
RMEIGAVLGAAPRRAVIRENSDPGDIIILLGGRTGRDGCGGATGSSKVHTEESIETCGAE
VQKGNAPTERKIQRLFRREEVSHLIKKCNDFGAGGVSVAIGELADGLRVELDKVPKKYAG
LDGTEIAISESQERMAVVVDPKDVDEFMAYAKEENLEATVVAVVTEDPRLVLVWRGKEIV
NLSRAFLDTNGAHQETDVEVEMPSRKDSLFIKKEVEDVKETWLNTLSDLNVCSQKGLVEM
FDGSIGAGSVFMPHGGKYQMTETQAMVAKVPVQNGTTDSVSMMSYGFDPYLSSWSPYHGA
VYAVTESVAKIVAAGGDYSKIRFTFQEYFRRMTEDPKRWSQPFAALLGAYAAQIGFGLPS
IGGKDSMSGTFQDIDVPPTLVSFAVDMALEQDIITPELKKAGNKLVWLKIERDENDLPVY
EKVMEQYGKIHEDIQKGRIVSAYALDRHGIASAVSKMAFGNRLGVQLETTVDKKDLFAPA
FGDLIAEVPAGEVENLVADYTEIGAVTEEAVLAYGDVTISLKEAEQAWTGTLEKVFATKS
AADSDKKVEEKLFNTADIHICSHKIGQPTVFIPVFPGTNCEYDSKRAFERAGAKVITKVF
RNLDAEDIRGSVGEFEKAIGQAQMIMFPGGFSAGDEPDGSAKFFATAFQNAKIKEAVEKL
LNERDGLALGICNGFQALIKLGLVPYGKIIGQTEDSPTLTYNTIGRHISKMVYTKVVTNK
SPWLQGAELGGVYTNPASHGEGRFVASEEWLDRLFANGQVATQYCDPEGKISMNEEWNVN
GSYRAIEGITSPDGRVLGKMAHSERRGDHVAINIYGEQDLKIFESGVKYFK
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atgagtaatgtaaagcgtgtgtatgtggaaaaaaagccggaatttgccgtaacagcgaaa
gggcttggacatgagatccgtcattatctcggaattaaagatgtgaccggggtacgggtt
ctgatccggtatgacgcagaaaatatatcagatgagacatttgaaaaagcatgtggcgga
gtgtttgcagagcctccggtcgatatcctttacagagaaagttttacaaagaatgagaca
gatcggtgcttttcagttgaatttcttccgggacagtttgaccagagagcagattcagca
gaacagtgtatcagatttatcaaagaagatgagacaccggtgatccgtacagcggtaact
tatgtgatcgagggaaatatatcagaggaagagtttgaagcaatcaagaatcactgcatc
aatccggtagattcaagagaagctgctgcagagaagccgaagacactggtaacggtattt
gaagaaccggcagatgtaaaggtatttgacggatttaaagatatgccggaggcagaactg
aaagagttgtatgattcacttggtcttgcgatgacgtttaaagatttccagcatatccag
aagtattatcatggagaggaagaccggaatccgacgatgacagagatccgtgtactggat
acttactggtcagatcactgccgtcatacgacattttctacagaattaaaagatgtaaaa
tttgatgacggagattacagagatgccatcgaggatacatataaagagtatctgaaagat
cacagtgagatctttaaaggaagagaagataagtttgtatgcctgatggatctggcactg
atggcaatgcgtcgtctaaaaaaagaaggaaagcttgcagatcaggaagagtccgatgag
atcaatgcgtgcagtatcgttgtaccgatcaaggtagacggtgtcgaggaagaatggctg
atcaattttaaaaatgagacgcacaaccatccgacagagattgagccgtttggtggagca
gctacctgccttggcggtgcaatccgtgatccgctgtcaggacgtacttatgtatatcag
gcgatgcgtgtgacgggagcggctgacccgacggtttcagcgaacgagacactgaaagga
aagcttccacagaaaaagctggtgcgtgaggctgcacatggatacagttcttacggaaac
cagatcggtcttgcaaccggactggtaaaagagatttaccatccggattatgtcgcaaag
cgtatggagatcggagcagtgcttggtgcagcaccgagacgtgcagtgatccgtgaaaat
tctgatccgggcgatatcattatcctgctgggtggtcgtaccggtcgtgacggatgcgga
ggagcaacaggttcttccaaggttcatacagaggagtccatcgagacatgcggagctgaa
gtgcagaagggaaatgcaccgacagagcgtaagatccagcgtctgttccgcagagaagaa
gtcagccatctgattaaaaagtgtaatgactttggtgccggaggagtttcagttgccatc
ggagaactggcagacggactgcgggtagagctggataaagtgccaaagaaatatgcagga
ctggacggaacagagatcgcgatttccgaatcccaggaaagaatggcagtcgttgtcgat
ccgaaagatgtagatgagtttatggcatatgcgaaagaggaaaatcttgaggcaacggtt
gtagcagtcgttacggaagatccgagactggttcttgtatggagaggaaaagagattgta
aacctttcccgtgcattccttgataccaacggggcacatcaggagacagacgtagaagta
gagatgccgtccagaaaagacagcctttttatcaaaaaagaagtagaagatgtaaaagag
acctggctgaatactctttctgatttaaatgtatgctctcagaagggtcttgtggaaatg
tttgacggttccatcggagccggatcagtgttcatgcctcatggcggaaaatatcagatg
acagagacgcaggcgatggtggcaaaagttccggtacagaatggtacaacggacagcgta
tccatgatgagttatggatttgatccgtatctgtcaagctggagtccgtatcacggagca
gtttatgcggtgacagaatcagttgcaaagatcgtggcagccggtggagattatagtaag
atccgttttacattccaggagtatttccgcagaatgaccgaagatccgaagagatggagc
cagccttttgctgcattgctcggagcgtatgcggcacagatcggatttggccttccgtca
atcggaggtaaggacagtatgtccggtacattccaggatattgatgttcctccgacactg
gtatcttttgcggtcgatatggcactggagcaggatatcatcacaccggaactgaaaaaa
gcgggaaataagcttgtatggcttaagattgagagagatgaaaatgatcttccggtttat
gagaaagtgatggagcagtatggaaagatccatgaagatattcagaaaggaagaatcgtt
tccgcttatgcacttgatcgtcatggaattgccagtgctgtaagtaagatggcatttggt
aacagactgggagttcagcttgagacaacggtggataaaaaggatctgttcgcaccggca
tttggtgatctcattgcagaggtacctgcgggagaagtggagaaccttgtggctgactat
acagagatcggagcagtaactgaggaagcagtgctggcatatggggatgtaacgatcagt
ctgaaagaggcagaacaggcatggacaggtactcttgaaaaagtatttgcaacaaagtct
gcagcagattctgataaaaaagtagaagaaaagttgtttaatacagcagatatccatatc
tgcagccataagatcggacaaccgactgtctttattcctgttttcccgggaacgaactgt
gagtacgacagtaaacgtgcatttgagcgggcaggagcaaaggtgattacgaaagtattc
cgtaatctggacgcagaggatatcagaggatctgttggtgaatttgaaaaagccatcgga
caggcacagatgatcatgttcccgggtggattcagtgcaggagatgaaccggatggttct
gccaaattctttgcaacagcattccagaatgcaaagattaaagaagcggtagagaaattg
ttgaatgaaagagacggactggcactgggaatttgtaatggattccaggcactgatcaag
ctggggcttgtaccatacggtaagatcataggtcagacggaagattcaccgaccctgaca
tacaataccatcggccgtcatatttctaagatggtttatacgaaagttgtaaccaataag
tccccatggctgcagggagcagagcttggcggagtctatacgaatccggcttcccatgga
gaaggaagattcgttgcaagtgaggaatggctggaccggcttttcgctaacggacaggtt
gcaacgcagtactgtgatcctgaaggtaagatcagcatgaatgaagagtggaatgttaat
ggttcctatcgtgcgattgaaggtatcacaagcccggacggacgtgtacttggtaagatg
gctcattcagaacgtcgtggggatcatgttgcgatcaatatttatggagaacaggatctg
aagatttttgaatcaggtgtaaaatattttaaataa
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