KEGG   Cupriavidus metallidurans: Rmet_5868
Entry
Rmet_5868         CDS       T00351                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
rme  Cupriavidus metallidurans
Pathway
rme00290  Valine, leucine and isoleucine biosynthesis
rme00660  C5-Branched dibasic acid metabolism
rme01100  Metabolic pathways
rme01110  Biosynthesis of secondary metabolites
rme01210  2-Oxocarboxylic acid metabolism
rme01230  Biosynthesis of amino acids
Module
rme_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:rme00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    Rmet_5868 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Rmet_5868 (leuC)
Enzymes [BR:rme01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     Rmet_5868 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     Rmet_5868 (leuC)
SSDB
Motif
Pfam: Aconitase AcnX
Other DBs
NCBI-ProteinID: ABF12727
UniProt: Q1LAU9
LinkDB
Position
megaplasmid:complement(63152..64474)
AA seq 440 aa
MTLPHGKTAVDPSQLPATLAQKLVARAAGVSHVTPGSVVMCKVDLAMSHDSSGPRRVAPL
LRELGAKVWDPSRFVVVTDHYVPAADPEAESILRFTRDWVREAGIQNFIDNEGICHVVLP
ERGHILPGRFIVGGDSHSPTGGAFGAYMFGIGATEMAGVLATGEIWLRVPNTIRVEWQGT
LSDGVCAKDIMLFLCATLGMAGGRYEVIEYTGSTVKTLSMQERMTLTNMSTELGAQTALI
APDATTMAWLADAGVDAATLAAIEPRQWRSDADAPVLATHRFDAGTLVPQVAAPHSPANS
GPVDQAAGAPIEIAYLGACTGAKLEDLRMAARVLRGRKVAPGVSLKVAPASLRDQQQAAT
EGTLGVLMDAGAELLPNACNACAGYGATRFPAGSRAIASTARNFPGRMGDAGSAVWLASP
MTVAASAATGCITDPRTLLA
NT seq 1323 nt   +upstreamnt  +downstreamnt
atgaccctgccgcacggcaagaccgcggtcgaccccagccaactgcccgccacactcgcc
cagaaactggtcgctcgtgcggcaggtgtgtcgcatgtcacgccgggatcggtggtgatg
tgcaaggtcgacctggccatgtcgcacgactcgagcggaccgcgccgcgtggcgccgctg
ctgcgcgaactcggcgcaaaggtctgggatccgtcccgcttcgtggtggtcaccgaccac
tacgtgcctgcggccgaccccgaagccgaatcgattctgcgcttcacgcgcgactgggtg
cgtgaagcgggcattcagaacttcatcgacaacgaaggcatctgccacgtggtgctgccc
gagcgcggccatatcctgcccggacgcttcatcgtcggcggcgacagccacagccccacg
ggcggcgcttttggcgcgtacatgttcggtatcggcgccacggaaatggccggtgtgctg
gccacgggggagatctggctgcgtgtgccgaacacgatccgggtcgagtggcaggggacg
ctgtcggacggcgtttgcgccaaggacatcatgctgttcctgtgcgccacgctgggtatg
gcgggtggccgctacgaagtgatcgaatacaccgggagcacggtaaagacgctgtcgatg
caggagcgcatgacgctcacgaacatgagcaccgaactcggcgcgcaaacggcgctgatc
gcgccggatgccacgacgatggcatggcttgccgatgccggcgtcgatgccgccacgctc
gccgcgatcgaaccgcgccagtggcgcagcgatgccgacgcaccggtactggccacacat
cgcttcgatgccggcacgctggtaccgcaggtagccgcgccgcattcgccggccaacagc
ggcccggtcgaccaggccgccggcgcgccgatcgagatcgcctatctgggcgcctgcacc
ggcgccaagctcgaagacctgcgcatggccgcgcgcgtgctgcgcgggcgcaaggtggca
ccgggcgtgtcgttgaaggtcgcgccggcctcgctgcgcgaccagcaacaagcggccacc
gaagggacgctcggcgtgctgatggatgccggcgcggagctgctgccgaacgcgtgcaat
gcgtgcgccggctacggcgccacacgctttccggccggcagccgcgccatcgcctcgacc
gcgcgcaacttccccggccgcatgggcgatgcaggtagcgccgtatggctggcatcgccc
atgaccgtggctgccagcgccgccaccggctgcatcactgacccacgcacgttactggca
tga

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