Rhodothermus marinus SG0.5JP17-172: Rhom172_2138
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Entry
Rhom172_2138 CDS
T01606
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
rmg
Rhodothermus marinus SG0.5JP17-172
Pathway
rmg00290
Valine, leucine and isoleucine biosynthesis
rmg00620
Pyruvate metabolism
rmg01100
Metabolic pathways
rmg01110
Biosynthesis of secondary metabolites
rmg01210
2-Oxocarboxylic acid metabolism
rmg01230
Biosynthesis of amino acids
Module
rmg_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rmg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Rhom172_2138
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Rhom172_2138
Enzymes [BR:
rmg01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Rhom172_2138
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
URO-D
Motif
Other DBs
NCBI-ProteinID:
AEN74040
LinkDB
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Position
complement(2425772..2427379)
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AA seq
535 aa
AA seq
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MKIELFDTTLRDGTQGEHVTLTVDDKIRIARRLDDFGIDVIEGGWPGSNPKDKEFFERAR
DIEWKHAQICAFGSTRRAGLAPEGDPNLRALLEAGTPTVAIFGKSWTLHARVALGVSLEE
NLELIASSVAYLKAHGRRVIYDAEHFFDGYQDDPAYALETLRAAAEAGADVLVLCDTNGG
TLPSDIYRIVGEVRRQFDVPLGIHTHNDTGCAVANTIMAVAAGARHVQGTINGIGERCGN
ADLCVVIPNLQLKMGFRCVPEEKLAQLTDLSRFVNEVANLTPIDRAPYVGRSAFAHKGGV
HVSAVMKDPRAYEHIPPEKVGNRRRVLVSDLSGKSNIQYKAAELGIELKEGEQARQAVQR
IKELEHLGYEFQGAEASFELLLRTIQGEDTRFFTLDRLRVRTEIDEDGGICNSEATLAIR
VQDARELVVAEGNGPVDALSNALRKALRCFYPDLDQVHLSDYKVRVLNSDDGTAAAVRVL
VEHRDGERRWHTVGVSTNILEASWQALADGIRYYLLKKRQGELAASAALASAQRT
NT seq
1608 nt
NT seq
+upstream
nt +downstream
nt
atgaagatcgaactcttcgacacgacgctgcgcgacggtacccagggcgaacacgttacg
ctgaccgtcgacgacaaaatccgcatcgcccgccgactggacgacttcggcatcgacgtg
atcgaagggggatggccgggctcgaatcccaaggacaaggaatttttcgagcgggcccgg
gacatcgaatggaagcacgcccagatctgcgcgttcggctccacgcgtcgggccgggctg
gcgcccgaaggcgatccgaacctgcgggcgcttctggaagccgggacgcccacggtggcc
atcttcggcaagagctggacgctgcatgcccgcgtcgcgctgggcgtctcgctcgaagag
aatctggagctgatcgcttcgtcggtggcctatctgaaggcgcacggccgccgcgtcatc
tacgacgccgagcactttttcgatggctatcaggacgatccggcctatgcgctggagacg
ctgcgcgcggcggccgaggccggtgccgacgtgctggtgctctgcgacacgaatggcggc
acgctcccgagcgacatctaccggatcgtgggggaggtgcgacgccagttcgacgtgccg
ctgggcatccacacgcacaacgacaccggctgcgccgtggccaacacaatcatggccgtg
gcggccggcgcccggcacgtgcagggcacgatcaacggcatcggcgaacgctgcgggaac
gcggacctgtgcgtggtcatcccgaacctgcagctcaagatgggcttccggtgcgtgccc
gaagagaagctggcccagctgacggacctttcccgcttcgtcaacgaagtggccaacctg
acgccgatcgatcgggcgccgtacgtggggcggagcgccttcgcgcacaagggcggcgtg
catgtctcggccgtcatgaaggatccccgggcttacgaacacatcccgcccgagaaggtg
ggcaatcgccgccgggtgctggtctcggacctgtcgggcaagagcaacatccagtataag
gccgccgagctgggcatcgaactcaaggaaggcgagcaggcccggcaggccgtgcagcgc
atcaaggagctggagcacctgggctacgaattccagggggccgaggcctccttcgagctg
ctgctgcgtacgatccagggcgaagacacgcgtttcttcacgctggatcggctgcgcgtg
cgaaccgaaatcgacgaggacggcggcatctgcaactcggaggccacgctggccatccgc
gtgcaggatgcgcgtgaactggtagtggccgagggcaacggaccggtcgatgcgctttcg
aacgcgctgcgcaaggcgttgcgctgcttctatccggatctcgaccaggtgcacctgagc
gactacaaggtgcgcgtgctcaactccgacgacggcacggccgcggccgtgcgcgtgctc
gtggaacaccgggacggcgagcgccgctggcacacggtgggcgtttcgacgaacatcctg
gaggcgagctggcaggcgctggccgacggcatccgctactacctgctgaagaagcggcag
ggcgagctggccgcttcggcggcgctggcttcggctcagcgcacgtaa
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