Ralstonia mannitolilytica: TK49_06160
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Entry
TK49_06160 CDS
T03778
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
rmn
Ralstonia mannitolilytica
Pathway
rmn00300
Lysine biosynthesis
rmn00550
Peptidoglycan biosynthesis
rmn01100
Metabolic pathways
rmn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
rmn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
TK49_06160
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TK49_06160
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TK49_06160
Enzymes [BR:
rmn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
TK49_06160
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Paralog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AJW44331
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Position
1:1289502..1290941
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AA seq
479 aa
AA seq
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MSAAQTVMMHATDAASWMAGAYLAGPDAAILRVTTDSRTVQPGDLFVALIGERFDAHDFL
PEVVARGAAAVLVSRAPAATLDMSNVAVLTVADTRVGLGELAAGWRRQFPIPVVAVTGSN
GKTTVKEMISAIFAHAVGEDARLATAGNFNNEIGLPLTLFRLNAQHRLAVLELGMNHPGE
TAVLAAIAQPTVAMINNAQREHQEFMVNVQAVAEEHAAVLAALPADGVAVFPRDAANGGE
FAPVWQAAAGSRRMLDFGIEAGAVKGAVTDAADGQRIDVQAEGQRFVITLPLLGLHNARN
ALAATACALAAGVAPEVIVQALGSFAPVKGRLQRKPGAHGGLVIDDTYNANPDSVRAAIE
ALITLPAPRWLVLGDMGEVGAQGPAFHAEIGAYARERGIDAVLATGELARHTVDAFGAGA
QHFASAEALIEHGVPAIGPGATVLVKGSRFMRMERIVEALVLKDPAATSAAGSSTQQKH
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgcccagaccgtgatgatgcacgcgaccgatgccgcttcctggatggcgggt
gcctacctggccggccccgatgcggccatcctgcgcgtcactaccgacagccgtaccgtg
cagcccggcgacctgtttgtcgcgctgatcggcgaacggtttgatgcccacgacttcctg
cccgaagtggtggcgcgcggcgcggccgccgtactggtgtcgcgcgcgccggccgccacg
ctggatatgtcgaacgtggccgttctgacggtagccgatacgcgcgtcgggctcggcgag
cttgcagcgggctggcgccgccagtttccgattcccgtggtggccgtgacgggcagcaac
ggcaagaccacggtcaaggagatgatctcggccatcttcgcgcacgccgtgggtgaagac
gcccgcctggcaaccgccggcaatttcaacaacgagatcggcctgccgctcacgctgttc
cgcctgaacgcgcaacacaggctggcggtgctcgaactcggcatgaaccacccgggtgag
accgccgtgctggccgccatcgcccagccgacggtggcgatgatcaacaacgcgcagcgc
gagcaccaggaattcatggtgaatgtgcaggccgtggccgaagaacacgccgccgtgctg
gcggcgctgccggctgacggcgtggcggtgttcccgcgcgacgcggccaacggcggtgag
tttgcgccggtatggcaggcggctgcgggttcgcgtcgcatgctcgatttcggcatcgag
gctggcgctgtgaagggcgccgtcaccgatgctgccgacggccagcgcatcgacgtgcag
gccgaggggcagcgcttcgtcatcacgctaccgctgcttgggttgcacaacgcgcgcaat
gcactggcggcaacggcgtgcgcgctggctgccggtgtggcgcccgaggtcatcgtgcag
gcgctcggcagcttcgcgccggtcaaggggcgactgcagcgcaagccgggcgcacacggc
ggcctcgtcatcgacgacacgtacaacgcgaatccggattcggtgcgcgccgcgatcgag
gcgctcatcacgctgccggcgccgcgctggctggtgctcggcgacatgggcgaggttggc
gcgcaggggccggcattccacgcggagatcggtgcctatgcgcgtgagcgcggcatcgat
gcggtgctggccaccggcgagcttgcacggcatacggtcgacgcgtttggcgcgggcgca
cagcatttcgcgtcggccgaagcgttgattgaacacggtgtgccggccatcgggcccggt
gcgacggtattggtgaagggctcgcgcttcatgcggatggaacgcattgtggaagcgctg
gtcttgaaagacccggctgcaacatcggccgccgggtcttccacgcaacagaagcattaa
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