Rhodothermus marinus DSM 4252: Rmar_0740
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Entry
Rmar_0740 CDS
T01119
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
rmr
Rhodothermus marinus DSM 4252
Pathway
rmr00290
Valine, leucine and isoleucine biosynthesis
rmr00620
Pyruvate metabolism
rmr01100
Metabolic pathways
rmr01110
Biosynthesis of secondary metabolites
rmr01210
2-Oxocarboxylic acid metabolism
rmr01230
Biosynthesis of amino acids
Module
rmr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
rmr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Rmar_0740
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Rmar_0740
Enzymes [BR:
rmr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Rmar_0740
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Agro_virD5
Motif
Other DBs
NCBI-ProteinID:
ACY47638
UniProt:
D0MG82
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Position
859997..861610
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AA seq
537 aa
AA seq
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MSDRIIIFDTTLRDGEQAPGASMTIDEKLRIAHQLARLNVDVIEAGFPISSPAQFEAVQR
IAAEVEGPVICALARAREEDIRAAAEALKPGKRTRIHTFIATSDIHIDAKFGDERYGRTL
AEKRRTILRLAEEAVRLARTFTDDVEFSAEDAGRTDVGYLAEVVQVAIEAGATTINLPDT
TGYCVPDEYAAMFREVIRRVQPPPHVIFSAHCHDDLGLAVANSLAAVQAGVRQIECTING
IGERAGNAALEEVVMALKVRGERFGRLQVNIVTQHLTETSRMVSMATGFPVPPNKAIVGR
NAFSHEAGIHQHGVLRRRDTYEIMRAEDVGQEPEQIRLGRHSGRHGLFSRLAKLGIEVPE
ERKEEVYRRFLALADLKKEIYDEDLRRLVAEQPDENPEALYQLMEMHVATGTHRAPEAEV
QILNRATNTLHIGRATGDGPVNAIYKAIDQAVGAAHELVSYELRSVTEGADAVGEVTVVI
DFNGTRFTGVARHTDVLRASADAYLEAINQLEQYRADRESVTFVRAGIMQSFGGAAA
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
atgagcgaccgtatcatcatcttcgacaccacgctgcgcgacggcgagcaggcgccgggc
gcttccatgacgatcgacgaaaagctgcgcattgcgcatcaactggcccggctgaacgtg
gatgtcatcgaggctggcttcccgatctcctcgccggctcagttcgaagccgtgcagcgc
atcgccgccgaggtggaaggtcccgtcatctgcgcgctggcacgggcgcgcgaagaggac
atccgggcggccgccgaagcgctcaagcccggcaaacgcacgcgcatccacacgttcatt
gccaccagcgacatccacatcgacgcgaaattcggcgacgagcgctacgggcgcacgctg
gccgaaaagcgccggacgatcctgcgtctggccgaagaggccgtccggctggcccgcacc
ttcaccgacgacgtggagttcagcgccgaggatgccggccgcaccgacgtgggctacctg
gccgaagtcgtgcaggtagctatcgaggccggcgctaccacgatcaacctgcccgatacg
accggctactgcgtgcccgacgagtacgcggccatgttccgggaagtaatccggcgggtg
cagccgcctccgcacgtcatcttctcggcgcactgccacgacgacctggggctggccgtg
gccaactcgctggcggccgtgcaggcgggcgtgcgccagatcgagtgcacgatcaacggc
atcggcgagcgggccggcaatgccgccctcgaagaggtcgtcatggcgctgaaggtgcgt
ggcgagcggtttggtcgcctgcaggtgaacatcgtcacgcaacacctgacggaaaccagc
cgcatggtgtcgatggccaccggctttccggtgccgcccaacaaggccattgtcggccgc
aacgccttcagccatgaggccggtattcaccagcacggcgtgctgcggcggcgcgatacc
tacgagatcatgcgcgccgaagacgtgggccaggagcccgaacagatccggctgggacgc
cactcggggcggcacggcctcttcagccgcctggccaaactgggtatcgaagttccggag
gagcgcaaggaggaagtctatcggcgcttcctggcgctggccgacctgaaaaaggaaatc
tacgacgaggatctgcgccgcctggtagcggagcaaccggacgaaaacccggaggcgctc
taccagctcatggaaatgcacgtcgcgaccggtacgcaccgggcaccggaggccgaggtg
cagatcctcaaccgggcgaccaatacgctgcacatcggacgggccaccggcgacggtccg
gtcaacgccatctacaaggcgatcgatcaggccgtgggagccgcgcacgagctggtcagc
tacgagctgcgttcggtcaccgaaggggccgacgccgtgggcgaggtgaccgtcgtgatc
gacttcaacggcacgcgcttcacgggcgtggcccggcacaccgacgtgctgcgcgcgtcg
gccgacgcctacctggaggccatcaaccagctcgagcagtaccgggccgaccgggaaagc
gtcacgttcgtacgtgccggtatcatgcaatcctttggcggtgcagccgcctga
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