| Entry |
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| Name |
Selenocompound metabolism |
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| Class |
Metabolism; Metabolism of other amino acids
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| Pathway map |
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| Reaction |
| R03595 | ATP:selenide, water phosphotransferase |
| R03596 | hydrogen selenide:NADP+ oxidoreductase |
| R03599 | L-selenocysteine selenide-lyase (L-alanine-forming) |
| R04770 | selenomethionine methanethiol-lyase (deaminating) |
| R04772 | S-adenosyl-L-methionine:L-methionine S-methyltransferase |
| R04773 | selenomethionine:tRNAMet ligase (AMP-forming) |
| R04929 | ATP:selenate adenylyltransferase |
| R04931 | S-adenosyl-L-methionine:thiol S-methyltransferase |
| R04941 | selenocystathionine L-homocysteine-lyase (deaminating) |
| R04944 | O-phosphorylhomoserine:selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-phosphorylhomoserine phosphate-lyase (adding selenocysteine) |
| R04946 | O4-succinyl-L-homoserine:L-selenocysteine Se-(3-amino-3-carboxypropyl)transferase; O-succinyl-L-homoserine succinate-lyase (adding selenocysteine) |
| R07229 | ferricytochrome c:selenite oxidoreductase |
| R08219 | selenophosphate:L-seryl-tRNASec selenium transferase |
| R08223 | L-seryl-tRNA(Sec) kinase |
| R08224 | selenophosphate:O-phospho-L-seryl-tRNA(Sec) selenium transferase |
| R09365 | 5-methyltetrahydropteroyltri-L-glutamate:L-selenohomocysteine Se-methyltransferase |
| R09366 | Se-methyl-L-selenocysteine methaneselenol-lyase (deaminating; pyruvate-forming) |
| R09369 | S-adenosyl-L-methionine:methaneselenol Se-methyltransferase |
| R09370 | S-adenosyl-L-methionine:dimethyl-selenide Se-methyltransferase |
| R09371 | S-adenosyl-L-methionine:hydrogen-selenide Se-methyltransferase |
| R09372 | methaneselenol:NADP+ oxidoreductase |
| R09373 | L-methionine:methylselenopyruvate aminotransferase |
| R13388 | quinone:selenite oxidoreductase |
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| Compound |
| C05336 | Selenomethionyl-tRNA(Met) |
| C05689 | Se-Methyl-L-selenocysteine |
| C05690 | Se-Methylselenomethionine |
| C05695 | gamma-Glutamyl-Se-methylselenocysteine |
| C06482 | L-Selenocysteinyl-tRNA(Sec) |
| C16638 | O-Phosphoseryl-tRNA(Sec) |
| C18893 | 1-Methylseleno-N-acetyl-D-galactosamine |
| C18905 | Methylselenocysteine Se-oxide |
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| Reference |
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| Authors |
Hoefig CS, Renko K, Kohrle J, Birringer M, Schomburg L |
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| Title |
Comparison of different selenocompounds with respect to nutritional value vs. toxicity using liver cells in culture. |
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| Journal |
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| Reference |
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| Authors |
McKenzie MJ, Hunter DA, Pathirana R, Watson LM, Joyce NI, Matich AJ, Rowan DD, Brummell DA |
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| Title |
Accumulation of an organic anticancer selenium compound in a transgenic Solanaceous species shows wider applicability of the selenocysteine methyltransferase transgene from selenium hyperaccumulators. |
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| Journal |
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| Reference |
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| Authors |
Pinto JT, Lee JI, Sinha R, MacEwan ME, Cooper AJ |
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| Title |
Chemopreventive mechanisms of alpha-keto acid metabolites of naturally occurring organoselenium compounds. |
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| Journal |
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| Reference |
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| Authors |
Suzuki KT, Kurasaki K, Suzuki N |
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| Title |
Selenocysteine beta-lyase and methylselenol demethylase in the metabolism of Se-methylated selenocompounds into selenide. |
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| Journal |
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| Reference |
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| Authors |
Gromer S, Gross JH |
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| Title |
Methylseleninate is a substrate rather than an inhibitor of mammalian thioredoxin reductase. Implications for the antitumor effects of selenium. |
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| Journal |
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| KO pathway |
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