Rattus norvegicus (rat): 100362738 Help Entry 100362738         CDS       T01003                                  Symbol Pkml1 Name (RefSeq) pyruvate kinase PKM-like   KO K00873   pyruvate kinase [EC:2.7.1.40] Organism rno  Rattus norvegicus (rat) Pathway rno00010   Glycolysis / Gluconeogenesis rno00620   Pyruvate metabolism rno01100   Metabolic pathways rno01200   Carbon metabolism rno01230   Biosynthesis of amino acids rno04922   Glucagon signaling pathway rno04930   Type II diabetes mellitus rno05165   Human papillomavirus infection rno05203   Viral carcinogenesis rno05230   Central carbon metabolism in cancer Module rno_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate rno_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     100362738 (Pkml1)    00620 Pyruvate metabolism     100362738 (Pkml1)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     100362738 (Pkml1)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     100362738 (Pkml1)    05230 Central carbon metabolism in cancer     100362738 (Pkml1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     100362738 (Pkml1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     100362738 (Pkml1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     100362738 (Pkml1)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:rno04147]     100362738 (Pkml1) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      100362738 (Pkml1) Membrane trafficking [BR:rno04131]  Autophagy   Chaperone mediated autophagy (CMA)    Selective cargos     100362738 (Pkml1) Exosome [BR:rno04147]  Exosomal proteins   Proteins found in most exosomes    100362738 (Pkml1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C HpcH_HpaI Motif Other DBs NCBI-GeneID:  100362738 NCBI-ProteinID:  XP_038951174 RGD:  2324120 LinkDB All DBs Position 16:77540986..77543027 Genome browser AA seq 531 aa AA seqDB search MPKPDSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEM LKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPILYRPVAVALDTKGPEIR TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL ISLQVKEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV FASVIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM LSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRLAPITSDPTEAAAVGAVEAS FKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLD AWAEDVDLRVNLAVNVGKTRGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt atgcccaagccagacagcgaagcagggactgccttcattcagacccagcagctccatgca gccatggctgacaccttcctggaacacatgtgccgcctggacattgactccgcacccatc acggcccgcaacactgggatcatctgtaccattggccctgcttcccgatctgtggagatg ctgaaggagatgattaagtctgggatgaatgtggctcggctgaatttctctcatggaacc catgagtaccatgcagagactatcaagaatgtccgtgcagccacagaaagctttgcatct gatcccattctctaccgacctgttgcggtggctctggatacaaagggacctgagatccgg actggactcatcaagggcagcggcaccgcagaggtggagctgaagaagggagccacactg aagatcaccctggacaacgcctacatggagaagtgcgacgagaacatcctgtggctggac tataagaacatctgcaaggtggtggaggtgggcagcaagatctacgtggacgatgggctc atctccctgcaggtgaaggagaaaggtgctgactacctggtgacagaagtggaaaatggt ggctccttgggcagcaagaagggcgtgaacctgcctggtgctgctgtggacctccctgct gtgtcagaaaaggacatccaggacctgaagtttggggtggagcaggacgtggacatggtg tttgcgtctgtcatccgcaaggcggctgacgtgcatgaggttaggaaggtcctgggagag aagggcaagaacatcaagatcatcagcaaaatcgagaaccatgaaggtgtccgcaggttt gatgagattttggaggccagcgatggaatcatggtagctcgtggtgacctgggcattgag attccggcagagaaggtcttcctagctcagaagatgatgattggacgatgcaaccgagct gggaagccagtcatctgcgccacccagatgctggagagcatgatcaagaagccacgcccc acccgtgctgaaggcagtgacgtggccaatgcagtcctagatggagctgactgcatcatg ctgtccggagaaacagccaaaggggactaccctctggaggctgttcgcatgcagcacctg attgcccgagaggcagaggctgccatctaccacttgcagttattcgaggaactccgccgc ctggcgcccattaccagcgaccccacagaagctgccgccgtgggtgccgtggaggcctcc ttcaagtgctgcagtggggccattatcgtgctcaccaagtctggcaggagtgctcaccaa gtggcccggtaccgcccaagggctcctatcattgctgtgacacgcaatccccagacagcc cgccaggcccatctgtaccgtggcatctttcctgtgctgtgtaaggatgccgtactggat gcctgggctgaggacgttgatcttcgtgtgaacttggccgtgaatgttggcaagacccga ggcttcttcaagaagggagatgtggtcattgtgctgactggatggcgccctggctctggc ttcaccaacaccatgcgtgtagtgcctgtaccatga

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