KEGG   Rattus norvegicus (rat): 114024
Entry
114024            CDS       T01003                                 
Symbol
Acsl3
Name
(RefSeq) fatty acid CoA ligase Acsl3
  KO
K01897  long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00061  Fatty acid biosynthesis
rno00071  Fatty acid degradation
rno01100  Metabolic pathways
rno01212  Fatty acid metabolism
rno03320  PPAR signaling pathway
rno04146  Peroxisome
rno04216  Ferroptosis
rno04714  Thermogenesis
rno04920  Adipocytokine signaling pathway
Module
rno_M00086  beta-Oxidation, acyl-CoA synthesis
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    114024 (Acsl3)
   00071 Fatty acid degradation
    114024 (Acsl3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    114024 (Acsl3)
  09143 Cell growth and death
   04216 Ferroptosis
    114024 (Acsl3)
 09150 Organismal Systems
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    114024 (Acsl3)
   03320 PPAR signaling pathway
    114024 (Acsl3)
  09159 Environmental adaptation
   04714 Thermogenesis
    114024 (Acsl3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:rno01004]
    114024 (Acsl3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    114024 (Acsl3)
Enzymes [BR:rno01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.3  long-chain-fatty-acid---CoA ligase
     114024 (Acsl3)
Lipid biosynthesis proteins [BR:rno01004]
 Acyl-CoA ligase
  Long/very long chain acyl-CoA ligase
   114024 (Acsl3)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   114024 (Acsl3)
  Exosomal proteins of breast cancer cells
   114024 (Acsl3)
SSDB
Motif
Pfam: AMP-binding AMP-binding_C
Other DBs
NCBI-GeneID: 114024
NCBI-ProteinID: NP_476448
RGD: 70552
Ensembl: ENSRNOG00000014718
UniProt: Q63151 A6JW67
LinkDB
Position
9:87563601..87613078
AA seq 720 aa
MNNHVSSTPSTMKLKQTIHPILLYFIHFIISLYTILTYIPFYFLCESKQEKPNHIKAKPV
SSKPDSAYRSVNSMDGLASVLYPGCDTLDKVFMYAKNKFKDKRLLGTREILNEEDEIQPN
GKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMIAAQACF
MYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK
PPTWSEFPKGVIVHTMAAVQALGVKADVDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMIS
HSNIIASITGMARRIPRLGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ
SSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQI
SKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES
TGAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQNVTMGYY
KNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA
LKNLPLIDNICAYANSYHSYVIGFVVPNQKELTELARTKGFNGTWEELCNSSEMENEVLK
VLSEAAISASLEKFEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
NT seq 2163 nt   +upstreamnt  +downstreamnt
atgaataaccacgtatcttcaacaccgtctaccatgaagctaaaacaaaccatccacccc
atacttttatatttcatacattttataatatcactctatactattttaacatacatccca
ttttattttttgtgtgagtcaaaacaagagaaaccaaaccacattaaagcaaagcctgtc
agttcaaaaccggactctgcatacaggtctgtcaacagtatggatggcttagcttcagta
ttgtatcctggctgcgacacacttgataaagtttttatgtatgcaaaaaacaaatttaag
gacaaaagactattgggaacacgtgagattttgaatgaggaagatgaaatacaaccaaat
ggaaaggtttttaaaaaggttattctggggcactataattggctttcctatgaagatgtc
ttcattcgagccctcgattttggaaatgggttacaaatgttgggccagaagccgaaggcc
aacatcgccatcttttgtgagaccagggctgagtggatgattgctgcgcaggcgtgtttc
atgtacaacttccagcttgttacactgtatgcgactctgggaggtccagccattgtccat
ggactgaatgagacagaggtgaccaacatcattactagtaaagaactcctgcaaacaaag
ctgaaggatatcgtctctttggtcccacgtctgcggcatatcattactgttgatgggaag
cctccaacctggtctgagttccccaagggcgtcattgtacacaccatggctgcagtgcag
gctctaggagtaaaggctgacgtggacaagaaagctcacagcaaaccactgccctcagat
attgcagtaatcatgtacacaagtggatccacaggaattccaaagggagtcatgatctca
cacagcaacatcattgcctctataacggggatggcgagaaggattccaagactgggagag
gaagatgtatacattggatatttgcccctggcacatgttctagaattaagcgctgagctt
gtgtgtctttctcatggatgccggattggctactcttcaccacagacattagcagatcag
tcttcaaaaataaagaaaggaagcaaaggagacacatccgttctgaagcccacgctgatg
gcggctgtgccggaaatcatggatcggatctacaaaaatgtcatgaataaagtgaatgaa
atgagtgcttttcaacgaaacttgtttattttggcatataattataagatggagcagatt
tcaaaagggtgtagtaccccactgtgtgaccgctttgttttccggaatgtccgaaggctg
ctgggtggaaatattcgcgttttattgtgcggtggtgctccactttctgcaacgacacag
cgattcatgaatatctgcttctgttgtcccgttggccaggggtatggactcacagaatct
actggggctggaacaattacagaagtgtgggactacaataccggcagagtgggagcacca
ttagtttgctgtgaaatcaaattaaagaactgggaggaaggtggctattttaatactgac
aaaccacatcccagaggtgaaattctgattggtggccaaaatgtgacaatggggtactac
aaaaatgaagcaaaaacaaaggccgatttctttgaagatgaaaacggacagaggtggctg
tgcactggcgatattggagagtttgaccctgatggctgcctcaagatcattgatcgtaaa
aaggaccttgtgaaactacaggcaggagagtatgtttctctaggcaaagttgaggcagct
ttgaagaacctcccactgatagataacatttgtgcatatgcaaacagttaccattcttac
gtaattggatttgttgtgccaaatcaaaaggaacttacggagctagctagaacgaaagga
tttaacggaacttgggaagagctgtgtaacagcagtgaaatggaaaacgaggtccttaaa
gtgctttctgaggctgctatttcagcaagtctggaaaagtttgaaatcccactgaaaatt
cgtttgagccctgacccatggactcccgaaactggtctggtgactgatgccttcaagttg
aaacgtaaagaacttaaaacacactaccaggcagacattgagcggatgtatggaagaaaa
taa

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