Rattus norvegicus (rat): 114859
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Entry
114859 CDS
T01003
Symbol
Eif2ak4
Name
(RefSeq) eIF-2-alpha kinase GCN2
KO
K16196
eukaryotic translation initiation factor 2-alpha kinase 4 [EC:
2.7.11.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04140
Autophagy - animal
rno05160
Hepatitis C
rno05162
Measles
rno05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
114859 (Eif2ak4)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
114859 (Eif2ak4)
05162 Measles
114859 (Eif2ak4)
05168 Herpes simplex virus 1 infection
114859 (Eif2ak4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
114859 (Eif2ak4)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
114859 (Eif2ak4)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: Other
PEK family [OT]
114859 (Eif2ak4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
RWD
HGTP_anticodon2
tRNA-synt_His
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
114859
NCBI-ProteinID:
NP_001099214
RGD:
1311439
Ensembl:
ENSRNOG00000006027
UniProt:
A6HPA6
A0A8L2Q433
LinkDB
All DBs
Position
3:125810207..125895574
Genome browser
AA seq
1649 aa
AA seq
DB search
MAGGRGAAGRGPAEPQESYSQRQDHELQALEAIYGSDFQDLRPDARGRVREPPEINLVLY
PQGLAGEEVYVQVELRVKCPPTYPDVVPEIELKNTKGLSNESVNLLKSHLEELAKKQCGE
VMIFELAHHVQSFLSEHNKPPPKSFHEEMLERQAQEKQQRLLEARQKEEQEQREILHEIQ
KRKEEIKEEKKRKEMAKQERLEITSLTNQDHASKRDPAGHRAAAILHGGSPDFVGNGKAR
AHSSGRSRRERQYSVCSGEASPGSCDILYFCVGSADQLMVHKGKCVGSDEQLGKVVYNAL
ETATGSFVLLYEWVLQWQKKMGPCLTSQEKEKIDKCKKQIQGAETEFSSLVKLSHPNIVR
YFAMNSREEKDSIVVDILAEHISGISLAAHLSHSGPVPMHQLRKYTAQLLAGLDYLHRNS
VVHKVLSTASVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRFSDSALPYKTGKKGD
VWRLGLLLLSLSQGQECEEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFIN
PQPKMPLVEQSPEDSGGQDYIETIIPSNQLPSAAFFTETQRQFSRYFIEFEELQLLGKGA
FGAVIKVQNKLDGCCYAVKRIPINPASRQFRRIKGEVTLLSRLHHENIVRYYNAWIERHE
RPAVPGTPPPDYIPQAQNSSATGGKASGDTEELGSVEAAAPPPILSSSVEWSTSAERSNS
ARFPVTGQDSSSDEEDEDERDGVFSQSFLPASDSDSDIIFDNEDENSKSQNQDEDCNEKD
SRHEIEPSVTTEAVHYLYIQMEYCEKSTLRDTIDQGLFRDTSRLWRLFREILDGLAYIHE
KGMIHRDLKPVNIFLDSDDHVKIGDFGLATDHLAFNAEGKQDDQAGDHVIKSDPSGHLTG
MVGTALYVSPEVQGSTKSAYNQKVDLFSLGIILFEMSYHPMVTASERIFVLNQLRDPTSP
KFPDDFEDGEHTKQKSVISWLLNHDPAKRPTAMELLKSELLPPPQMEESELHEVLHHTLA
NTDGKAYRTMMSQLFCQHSSPAIDYTYDSDILKGNFLIRTAKIQQLVCETIVRVFKRHGA
VQLCTPLLLPRNRQIYEHNEAALFMDHSGMLVMLPFDLRVPFARYVARNNILNLKRYCIE
RVFRPRKLDRFHPKELLECAFDIVTSTANSSLPTAETIYTIYEVIQEFPALQERNYSIYL
NHTMLLKAILLHCGIPEDKLSQVYVILYDAVTEKLTRREVEAKFCNLSLSSNSLCRLYKF
IEQKGDLQDLTPTINSLIKQKTGIAQLVKYSLKDLEEVVGLLKKLGVKLQVSINLGLVYK
VQQHNGIIFQFLAFSKRRQRVVPEILAAGGRYDLLIPKFRGPQALGPVPTAVGVSIAIDK
IFAAVLNMGEPVTVSSCDLLVVSAGQMSMSRAINLTQKLWTAGITAEIMYDWSQSQEELQ
EYCRHHEITYVALVSDKEGSHVKVKSFEKERQTEKRVLESDLVDHVMQKLRTKVGDERNF
RDASDNLAVQTLKGSFSNASGLFEIHGTTVVPTVSVISPEKLSASTRRRHEIQVQTRLQT
TLANLHQKSSEIEILAVDLPKETILQFLSLEWDADEQAFNTTVKQLLSRLPKQRYLKLVC
DEIYNIKVEKKVSVLFLYSYRDDYYRILF
NT seq
4950 nt
NT seq
+upstream
nt +downstream
nt
atggctgggggccgcggggccgcaggacgcggcccggctgagccgcaggagagctattca
cagagacaggaccacgagctgcaggccctggaggcgatttacggctcggacttccaggat
ctgcggccggatgcgcgcggacgggtgagagagcctcctgaaatcaatttagttctgtac
cctcagggcctggctggtgaggaagtgtacgtgcaggtggagctgagggtcaaatgccca
ccgacatacccggatgtagttcccgaaatagagttaaaaaacactaaaggtctgtcgaat
gagagtgttaatttgttaaagtcacacctggaagaactggccaaaaagcagtgtggagag
gtgatgatattcgaactggcacaccacgtgcagtcgtttctcagcgagcataacaagccc
cctccaaagtctttccatgaagaaatgctggaaaggcaggctcaggagaagcagcagagg
ttgctggaggccaggcagaaagaggagcaggagcaacgtgaaatcctccacgagattcag
aaaaggaaagaggagatcaaggaagagaagaaaaggaaggaaatggctaagcaggaacgt
ttggaaattactagtttgacaaaccaggatcatgcctctaagagagacccagcaggacac
agggcagctgccattctccatggaggctctcctgactttgtaggaaatggtaaagcccgg
gcacactcctcaggaaggtccaggcgagaacgtcagtattctgtctgtagtggtgaagcc
tctcctggctcgtgtgacatcctctacttctgtgtgggtagcgctgatcagctcatggtg
cacaaagggaaatgtgttggcagcgatgagcagctggggaaggtggtatacaatgcattg
gaaacagccacgggcagctttgtcttgttgtatgagtgggtccttcagtggcagaaaaag
atgggcccttgccttaccagtcaagagaaagagaagatcgataaatgtaaaaagcagatt
caaggagcagaaacagaattcagctccctagtgaaactgagccatccaaacattgtccgc
tactttgcgatgaactccagagaggagaaggattccattgtggtcgacattctggcagaa
cacatcagtgggatctctctcgctgcacacctgagccactcaggccctgtgcccatgcac
cagctgcgcaaatacacagcgcagctcctggcgggcctggactacctgcaccgcaactcg
gtggtgcacaaggtgctgagcaccgccagcgtcttggtggatgctgagggcaccgtcaag
ataacagactacagcatctctaagcgcctggcagacatttgcaaggaggatgtttttgag
caaactcgagttcgctttagtgacagtgctctgccttataaaaccgggaagaaaggggat
gtgtggcgtcttggcctcctgctgttgtctcttagccaaggtcaggagtgtgaggagtat
cctgtgaccatccccagtgatctgccagctgacttccaggacttcctgaagaagtgtgtt
tgcctggacgacaaggaaaggtggagccctcaacagttgctgaaacacagctttataaac
cctcagccaaaaatgcctttggtggagcagagtcctgaagattctgggggacaagattac
atcgagaccatcatccccagcaaccagctgcccagcgctgcgttcttcactgagacacag
agacagttctctcgatacttcattgagtttgaagaactacagcttctggggaaaggagct
tttggagctgtcatcaaggtgcaaaacaagcttgatggctgttgctatgctgtgaagcgc
atccctatcaaccctgcaagcaggcagttccgcaggatcaagggcgaggtgacgctgcta
tcgcgcctgcaccatgagaacattgtacgctactacaacgcctggatcgaacggcatgag
cgcccagcggtgccagggacaccacccccagactacataccccaggcccagaacagctca
gccaccggcgggaaagcatcaggcgacactgaggaactgggcagcgtggaggctgcagca
ccaccgcccatcctcagcagctcagtggagtggagcacatctgcagagcgctctaacagc
gcccgtttcccagtcacaggccaggactccagcagcgatgaggaagatgaggacgagcgc
gatggtgtcttctcacagtcctttctacctgcttcagattctgacagtgacatcatcttt
gacaatgaagatgaaaacagtaaaagtcagaatcaggatgaagactgcaatgaaaaggac
agtcgccatgagattgagccatcagtgacgaccgaggctgtgcactacctgtacatccag
atggagtactgcgagaagagcacactgcgagacaccattgaccaggggctgttccgagac
accagccggctctggaggcttttccgagagattctggatggattagcttatatccatgag
aaaggaatgattcaccgggatttgaagcctgtcaacatttttttggattctgatgaccat
gtgaaaataggtgattttggtttggcaacagaccatctggccttcaatgctgaaggtaaa
caggacgaccaagcaggtgatcatgtgattaagtcagacccttcaggccatttgactggc
atggttggcaccgctctgtatgtaagccctgaggtccaaggaagtaccaagtctgcgtac
aaccagaaagtggatctcttcagcctgggaattatcctctttgagatgtcgtatcacccg
atggtgactgcctcagaaagaattttcgttctcaaccaacttcgagatcccacgtcaccc
aagttcccagacgactttgaggacggagagcatacaaagcagaaatctgtcatctcctgg
ctgttaaaccatgatccagccaaacggcccacagccatggagctgctcaagagtgagctg
ctccccccaccacagatggaggagtcggagctgcatgaagtgctgcaccacacgctggcc
aacacggatgggaaggcctaccgcaccatgatgagccagctcttctgccagcacagctcc
cccgccatagactacacctacgacagcgacatcctgaagggcaacttcttgattcgcaca
gccaagatccagcagcttgtgtgtgaaaccatcgtccgcgtcttcaaaaggcatggagct
gtccagctgtgcaccccgctgctgcttccccgaaacaggcaaatatatgagcacaacgaa
gccgctctgttcatggatcacagtggcatgctggtgatgcttcctttcgacctgcgggtc
ccttttgcaagatatgtggcaagaaataacatactgaatttaaagcgatactgcatagag
cgggtgttcagacctaggaagttagaccgatttcatcccaaagaactcctggaatgtgca
tttgacatcgtcacttctaccgccaacagctccctgcccactgctgaaaccatctacacc
atctatgaagtcatccaggagtttcctgcacttcaggaaagaaattacagcatttacttg
aaccatacaatgctcctaaaggcaatactcctacactgtgggatcccagaggataaactc
agtcaagtctacgttattctgtatgatgctgtgacagagaagctgactaggagggaagta
gaagctaagttctgtaacctgtccttgtcatctaatagtctgtgtcgactctataagttc
atcgagcagaagggggatttgcaagacctaacgccgaccataaactcactaataaaacag
aaaacaggcattgctcagctggtgaagtatagcttaaaagacctagaggaagttgtcggg
ctgctgaagaaacttggcgtgaagttgcaggtctccatcaacctgggcttggtttacaag
gtgcagcagcacaatggcatcatcttccagttcctggcattcagcaaacgcaggcagagg
gttgtgcctgagatccttgcagctggtggcagatatgacctgctgattcccaagttcaga
ggcccacaggctctggggccagtgcccactgctgtcggtgtcagcatagccatagacaag
atattcgccgctgtcctcaacatgggagagcctgttacagtgagctcctgtgacctcctg
gttgtcagtgctggccagatgtccatgtccagggccatcaacctaacccagaaactctgg
acggccggcatcactgcagagatcatgtatgactggtcacagtcccaggaagagttacaa
gaatactgcagacatcacgaaatcacctatgtggccctggtctctgataaagaaggaagc
catgtcaaggtcaagtcctttgagaaggagaggcaaacagaaaaacgtgtgttggaatca
gatcttgtggaccatgttatgcagaaactaaggaccaaagttggtgacgaaaggaatttc
agagacgcttctgataatcttgccgtacaaactctgaaggggtcgttttctaatgcttca
ggtttgtttgaaatccatggaacaacagtagtccccactgtgagtgttatatcaccagaa
aaactgtcggccagcaccaggaggcgacatgagattcaggtgcaaacccgacttcagact
acccttgccaatttacatcagaaaagcagtgaaattgaaattttggctgtggatctaccc
aaggagaccatcttacagtttctatcgctagagtgggacgctgatgaacaggcatttaac
acaaccgtgaaacagctgctgtcacgcctgccaaagcaaagatacctcaaactcgtctgc
gacgaaatctataacatcaaagttgagaagaaggtgtcggtgttgttcctgtacagctac
agagatgactactacagaatcctattctga
DBGET
integrated database retrieval system
