Rattus norvegicus (rat): 140693
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Entry
140693 CDS
T01003
Symbol
Plcd4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4
KO
K05857
phosphatidylinositol phospholipase C, delta [EC:
3.1.4.11
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00562
Inositol phosphate metabolism
rno01100
Metabolic pathways
rno04020
Calcium signaling pathway
rno04070
Phosphatidylinositol signaling system
rno04919
Thyroid hormone signaling pathway
rno04933
AGE-RAGE signaling pathway in diabetic complications
Module
rno_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
140693 (Plcd4)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
140693 (Plcd4)
04070 Phosphatidylinositol signaling system
140693 (Plcd4)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
140693 (Plcd4)
09160 Human Diseases
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
140693 (Plcd4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
140693 (Plcd4)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
140693 (Plcd4)
Membrane trafficking [BR:
rno04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
140693 (Plcd4)
Endocytosis
Macropinocytosis
Phospholipase C
140693 (Plcd4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
EF-hand_like
C2
EF-hand_10
PH
EF-hand_7
EF-hand_1
PH_12
EF-hand_6
EF-hand_5
GDPD
EF-hand_15
DUF3939
EF-hand_8
Motif
Other DBs
NCBI-GeneID:
140693
NCBI-ProteinID:
NP_542419
RGD:
621025
Ensembl:
ENSRNOG00000016361
UniProt:
Q62711
LinkDB
All DBs
Position
9:83564616..83613742
Genome browser
AA seq
772 aa
AA seq
DB search
MASQIQKLLTTNQDLLLMQKGTMMRKVRTKSWKKLRYFRLQDDGMTVWHGRHLESISKPT
FSISDVERIRKGQDSELLRYLVEEFPLEQGFTIVFNGRRPNLDLVANSVEEAQTWMRGLQ
LLVDLVARMNYQEQLDQMLREWFQQADRNQDSRMSFREAQRLLLLMNVEMDEEYAFSLFQ
EADVSQSNTLDSEEFVQFYKALTKRTEIEELFENFSSDKQKLTLLEFVDFLREEQKESDH
SSDLALKLIDRYEPSENGRLLRVLSKDGFLSYLCSADGNIFNPDCLPIYQDMTQPLSHYY
INSSHNTYLLGDQFCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGRTLTSRILF
KDVLATLAQYAFQSSDYPLILSLDNHCTWEQQKTMAHHLIAILGEQLLSTTLEEQLIDIM
PSPEQLRGKILVKGKKLRTIEVVESDKEEEELEKDEGSDLDPASAELDMQSQPESQEQAS
GNKSKNKKKFLLQSSTTILCPDLSALVVYLRTAPFCSFTHSKENYHIYDISSFSESKAKN
LIREAGNEFVQHNARQLCRVYPSGLRTDSSNYNPQEHWNVGCQMVAMNMQTAGSAMDICD
GLFRQNGGSGYVLKPEFLRDTQSSFNPMKPVSLYKAQILVVQVISGQRLPKVDKTKETTV
VDPLVRVELYGVPEDTKQQETSYVENNGINPYWGETFYFQIQVPELAMLRFVVKDYSRTS
RNNFIGQYTLPWTCMKHGYRHVSLLSKDGTSLHPASIFVYTCMQEDLDMDEP
NT seq
2319 nt
NT seq
+upstream
nt +downstream
nt
atggcatctcagattcaaaagctactgaccactaatcaggacctgctgctgatgcaaaaa
ggaacgatgatgcgcaaggtgaggaccaaaagctggaagaagctaagatacttcagactt
caggatgacggcatgacggtctggcatgggcggcaccttgaaagcatatccaagcccact
ttttcaatctctgatgtggagaggatccgtaagggccaggattctgagctgttgcgctat
ctggtggaagagttccccctggagcaaggcttcaccattgtctttaatgggcgccgcccc
aacctggacctagtggccaacagtgttgaagaggcccagacttggatgcgaggactccag
ctgttggtggatctcgtcgccagaatgaactaccaggagcagctggatcaaatgttgaga
gaatggttccaacaagcagacagaaaccaggacagccggatgagtttcagagaagctcaa
cggctgctgcttctgatgaatgtggaaatggatgaagaatatgccttcagtctttttcag
gaagcagatgtttcccaatctaatactctggattcagaagaatttgtacagttctataag
gccctgactaagcgcactgagattgaagaactatttgagaacttttcatctgacaaacag
aagctgaccttgctggaatttgtagatttccttagagaggaacagaaagaaagcgaccat
tcctctgaccttgctctgaaactcattgaccgctatgagccttctgagaatggcagattg
ctacgtgtgctgagcaaggatggcttcctcagctacctctgctcagcggatggaaacatc
ttcaaccccgactgcctccctatctatcaggatatgactcagcctctgagtcactactac
atcaactcctctcacaacacctacctactgggtgaccagttttgtggccagagcagcgtt
gaaggatacatacgggccttgaaacgggggtgccgctgtgtggaggtggatacatgggac
ggacctgacggagagcccgttgtttatcatgggcgtacactgacctctcgtatcctgttc
aaagatgttttggcaacattagcacaatatgccttccagtcgtcagactacccactcatc
ttatctctggataaccactgcacttgggaacagcagaagaccatggcacaccatctgatt
gcgatcctgggagagcagctgctgagtaccaccctagaggaacaactgattgatataatg
ccctcgccagagcagcttcgggggaagatcttggtaaaaggaaagaagttgagaacaatt
gaggttgttgagtctgacaaggaggaagaagagctggagaaagatgaggggtcagatctg
gacccagcctccgctgagcttgacatgcagtctcagcccgagtcccaggagcaggcctct
gggaacaagagcaagaacaagaagaagtttcttctccagagttccacaaccatcctatgc
ccagacctatctgccctggttgtctacttgaggactgctcccttctgcagcttcactcac
tccaaagaaaactaccacatctacgacatttcatccttttctgagtccaaggccaagaac
ctcatcagggaggcaggcaatgagtttgtacagcacaatgccagacagctatgccgtgta
taccccagtggtctgaggacagattcatcgaactataacccccaggaacactggaatgtt
ggctgccaaatggtggccatgaacatgcagactgcaggaagtgcaatggacatctgtgat
gggctcttccgccagaatgggggctctggctatgtgctgaagccagaattcctgagagat
acccagagttccttcaatcccatgaagcccgttagtctttataaagcccagatccttgta
gtccaggtgatcagtggtcaaagactccccaaagtggacaaaaccaaagagacaaccgtt
gtggatccactggtgagagtagagctctatggtgttcctgaagacacaaagcagcaagag
accagctatgtggagaacaatggtattaatccatactggggggagacattctatttccag
atccaggtgcctgaacttgctatgctgcgttttgtggtaaaggattatagcaggacatcc
cgaaataactttataggccaatacaccctgccttggacctgcatgaaacatggctaccga
catgtatccttgctctccaaagacggcactagcctccatccagcctccatctttgtgtac
acctgcatgcaagaagacctggatatggatgagccctga
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