Rattus norvegicus (rat): 157074
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Entry
157074 CDS
T01003
Symbol
Sdha
Name
(RefSeq) succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00020
Citrate cycle (TCA cycle)
rno00190
Oxidative phosphorylation
rno01100
Metabolic pathways
rno01200
Carbon metabolism
rno04714
Thermogenesis
rno04932
Non-alcoholic fatty liver disease
rno05010
Alzheimer disease
rno05012
Parkinson disease
rno05014
Amyotrophic lateral sclerosis
rno05016
Huntington disease
rno05020
Prion disease
rno05022
Pathways of neurodegeneration - multiple diseases
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05415
Diabetic cardiomyopathy
Module
rno_M00009
Citrate cycle (TCA cycle, Krebs cycle)
rno_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
rno_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
157074 (Sdha)
09102 Energy metabolism
00190 Oxidative phosphorylation
157074 (Sdha)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
157074 (Sdha)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
157074 (Sdha)
09164 Neurodegenerative disease
05010 Alzheimer disease
157074 (Sdha)
05012 Parkinson disease
157074 (Sdha)
05014 Amyotrophic lateral sclerosis
157074 (Sdha)
05016 Huntington disease
157074 (Sdha)
05020 Prion disease
157074 (Sdha)
05022 Pathways of neurodegeneration - multiple diseases
157074 (Sdha)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
157074 (Sdha)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
157074 (Sdha)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
157074 (Sdha)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Thi4
Pyr_redox_2
GIDA
HI0933_like
DAO
FAD_binding_3
Motif
Other DBs
NCBI-GeneID:
157074
NCBI-ProteinID:
NP_569112
RGD:
621557
Ensembl:
ENSRNOG00000013331
UniProt:
Q920L2
A6JUU5
LinkDB
All DBs
Position
1:30764553..30789523
Genome browser
AA seq
656 aa
AA seq
DB search
MAGVGAVSRLLRGRRLALAGATRGFHFSVGESKKASAKVSDAISTQYPVVDHEFDAVVVG
AGGAGLRAAFGLSEAGFNTACLTKLFPTRSHTVAAQGGINAALGNMEEDNWRWHFYDTVK
GSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLKFGKGGQAHR
CCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCIEDGSIHRIR
AKNTIIATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTGIYGAGCLIT
EGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGPEKDHVYLQL
HHLPPEQLATRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKGQVLKHVNGQ
DQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGDKVPPIKANA
GEESVMNLDKLRFADGSVRTSELRLSMQKSMQSHAAVFRVGSVLQEGCEKVSQLYGDLQH
LKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKVRIDEYDYSK
PIEGQQKKPFAEHWRKHTLSYVDTKTGKVTLDYRPVIDKTLNEADCATVPPAIRSY
NT seq
1971 nt
NT seq
+upstream
nt +downstream
nt
atggccggggttggcgcagtttcgagacttcttcgcgggcggcgcttggctctagctggg
gcgactcgtggctttcacttctctgttggtgagagcaagaaggcatccgctaaagtttca
gacgcgatttctacccagtaccccgtggtggaccatgagtttgatgctgtggttgtaggt
gcaggcggggcaggcttgcgagctgcattcggcctttctgaggcaggctttaacacggca
tgccttacaaagctctttcctacccgctcacatactgttgcagcacagggaggtatcaat
gctgccctggggaacatggaagaggacaactggagatggcatttctatgacaccgtgaaa
ggctctgactggctgggggatcaggatgccatccattacatgacagagcaagctcctgcc
tccgtggttgagctagaaaattacggtatgccgtttagcaggactgaagatgggaggatt
tatcagcgtgcatttggtggacagagcctcaagttcgggaaaggcgggcaggcccatcgg
tgttgctgtgtcgctgatcggacgggccactcactcttacacaccttgtatggacgatct
ctgcggtatgacaccagttattttgtggagtatttcgcactggatcttctgatggaaaat
ggggagtgccgtggtgtcattgcactgtgcatagaagatgggtccatacaccgaataaga
gcaaagaacactattattgctactgggggctatgggcgaacctacttcagctgtacttct
gcccacaccagcacaggggacggcacagccatggtcactcgggctggtttaccttgccag
gacttagaatttgttcagttccaccccacaggtatctatggtgctggctgcctcatcaca
gaagggtgccgtggagagggaggcattctcatcaacagccaaggcgaaaggttcatggag
agatatgcccctgttgccaaggacctagcatcaagagatgttgtgtctcgatccatgact
ctcgagatccgtgaaggaagaggctgtggccctgagaaggatcacgtctacctgcagttg
caccatctgccccctgagcagctggccacgcgtctgcctgggatctcagagacggccatg
atcttcgccggcgtggatgtcaccaaggagcccattccagtccttcccactgtgcattac
aacatgggcgggattcccactaactacaagggacaggtgctgaagcacgtgaacggccag
gatcagattgtgcctggtctgtacgcctgtggggaggctgcctgcgcctcagtgcatggt
gccaaccggcttggagcaaactctcttttggaccttgtcgtctttggccgagcctgtgcc
ctgagcattgcagaatcttgcaggcctggagataaagttcctccgattaaggcaaatgct
ggagaagagtcggttatgaatcttgacaagttgagatttgctgatggaagtgtaagaaca
tcagagctgcgcctcagcatgcagaagtcgatgcagagccatgccgccgtgttccgtgtg
ggaagtgtgctgcaagaaggctgtgaaaaagtcagccagctctatggagacctacagcat
ctgaagacgtttgacaggggaatggtctggaacacagacctggtggagacgctggagctg
cagaatctgatgctgtgcgcactgcagaccatatatggtgcggaagcacggaaggagtca
cggggagctcatgccagggaagattacaaggtgcggattgatgagtatgattactccaag
cccatcgagggccagcagaagaagccatttgcggaacactggaggaagcacaccctctca
tatgtggacaccaagactgggaaggttactttggattacagacctgttattgacaagacc
ttgaatgaggctgactgtgctactgtacctcctgctatccgttcctactga
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