Rattus norvegicus (rat): 24255
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Entry
24255 CDS
T01003
Symbol
Cftr
Name
(RefSeq) cystic fibrosis transmembrane conductance regulator
KO
K05031
cystic fibrosis transmembrane conductance regulator [EC:
5.6.1.6
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno02010
ABC transporters
rno04024
cAMP signaling pathway
rno04152
AMPK signaling pathway
rno04530
Tight junction
rno04971
Gastric acid secretion
rno04972
Pancreatic secretion
rno04976
Bile secretion
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
24255 (Cftr)
09132 Signal transduction
04024 cAMP signaling pathway
24255 (Cftr)
04152 AMPK signaling pathway
24255 (Cftr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
24255 (Cftr)
09150 Organismal Systems
09154 Digestive system
04971 Gastric acid secretion
24255 (Cftr)
04972 Pancreatic secretion
24255 (Cftr)
04976 Bile secretion
24255 (Cftr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
rno02000
]
24255 (Cftr)
Enzymes [BR:
rno01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.1 Enzymes altering polypeptide conformation or assembly
5.6.1.6 channel-conductance-controlling ATPase
24255 (Cftr)
Transporters [BR:
rno02000
]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC7 subgroup
24255 (Cftr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ABC_membrane
CFTR_R
ABC_tran
AAA_29
AAA_21
SMC_N
RsgA_GTPase
TsaE
T2SSE
DUF87
NTPase_1
MeaB
NB-ARC
MMR_HSR1
DO-GTPase2
nSTAND3
Intein_splicing
AAA_23
Motif
Other DBs
NCBI-GeneID:
24255
NCBI-ProteinID:
NP_113694
RGD:
2332
Ensembl:
ENSRNOG00000055103
UniProt:
P34158
A6IE40
LinkDB
All DBs
Position
4:47422084..47694646
Genome browser
AA seq
1476 aa
AA seq
DB search
MQKSPLEKASFISKLFFSWTTPILRKGYRHHLELSDIYQAPSSDSADHLSEKLEREWDRE
QASKKKPQLIHALRRCFVWRFVFYGVLLYLGEVTKAVQPVLLGRIIASYDPDNTEERSIA
IYLGIGLCLLFIVRTLLLHPAIFGLHHIGMQMRIAMFSLIYKKTLKLSSRVLDKISIGQL
ISLLSNNLNKFDEGLALAHFIWIAPLQVVLLMGLLWDLLQFSAFCGLGLLIVLVIFQAIL
GKMMVKYRDKRAAKINERLVITSEVIDNIYSVKAYCWESAMEKIIESLREEELKMTRRSA
YMRFFTSSAFFFSGFFVVFLSVLPYTVINGIVLRKIFTTISFCIVLRMSVTRQFPTAVQI
WYDSLGMIRKIQDFLQTQEYKVLEYNLMFTGLVMENVTAFWEEGFQELLEKVQLNNDDRK
TSNGENHLSFSHLCLVGNPVLKNINLNIKKGEMLAITGSTGAGKTSLLMLILGELEASEG
IIKHSGRVSFSSQISWIMPGTIKENIIFGVSYDEYRYKSVVKACQLQEDITKFAEQDNTV
LGEGGVTLSGGQRARISLARAVYKDADLYLLDSPFGYLDVLTEEQIFESCVCKLMASKTR
ILVTSKMEQLKKADKILILHEGSSYFYGTFSELQSLRPDFSSKLMGYDTFDQFTEERRSS
ILTETLRRFSVDDASTTWNKAKQSFRQTGEFGEKRKNSILSSFSSVKKISIVQKTPLSIE
GESDDLQERRLSLVPDSEHGEAALPRSNMITAGPTFPGRRRQSVLDLMTFTPSSVSSSLQ
RTRASIRKISLAPRISLKEEDIYSRRLSQDSTLNITEEINEEDLKECFFDDMVKIPTVTT
WNTYLRYFTLHRGLFAVLIWCVLVFLVEVAASLFVLWLLKNNPVNGGNNGTKIANTSYVV
VITSSSFYYIFYIYVGVADTLLALSLFRGLPLVHTLITASKILHRKMLHSILHAPMSTFN
KLKAGGILNRFSKDIAILDDFLPLTIFDFIQLLFIVVGAIIVVSALQPYIFLATVPGLAV
FILLRAYFLHTSQQLKQLESEGRSPIFTHLVTSLKGLWTLRAFRRQTYFETLFHKALNLH
TANWFMYLATLRWFQMRIDMIFVLFFIVVTFISILTTGEGEGTTGIILTLAMNIMSTLQW
AVNSSIDTDSLMRSVSRVFKFIDIQTEESICTKIMKELHSEDSPNALVIKNEHVKKCDTW
PSGGEMVVKDLTVKYVDDGNAILENISFSISPGQRVGLLGRTGSGKSTLLSAFLRMLNIK
GEIQIDGVSWNSMTLQEWRKAFGVITQKVFIFSGTFRQNLDPNGKWRDEEIWKVADQVGL
KSVIEQFPGQLNFTLVDGGYVLSHGHKQLMCLARSVLSKAKIILLDEPSANLDPITYQVI
RRVLRQAFAGCTVVLCEHRIEAMLDCQRFLVIEQGNVWQYESLQALLSEKSVFQRALSSS
EKMKLFHGRHSSKQKPRTQITAVKEETEEEVQETRL
NT seq
4431 nt
NT seq
+upstream
nt +downstream
nt
atgcagaagtcgcctctggagaaagccagctttatctccaaactcttcttcagctggacc
acaccaattttgagaaaagggtacagacaccacttggagctgtcagacatataccaagcc
ccttcttctgattcagctgaccacctgtctgaaaagctagaaagagaatgggacagggaa
caagcttccaaaaagaagccccagcttatccacgccctccggcgatgctttgtctggaga
ttcgtcttctacggagtcttgttatacctcggggaagtcaccaaggctgtccagcctgtc
ttgctaggaagaatcatagcatcctatgatccagacaacacggaggagcgttccattgcc
atttacctaggcataggcttatgcctcctcttcattgtcaggacactgcttctgcaccca
gctatttttggccttcatcacattggaatgcagatgagaatagccatgtttagcttgatt
tataagaagactttaaagttgtcaagccgtgttcttgataaaataagtattggacaactt
attagtcttctttccaacaacctgaacaaatttgatgaaggacttgccttggcacatttt
atatggattgctcctttacaagtggttcttctgatggggcttctctgggacttgttacag
ttctcagccttctgtggccttggtttactgatagtcttggttatttttcaagctatctta
gggaagatgatggtgaagtacagagataaaagagctgcaaagatcaatgaaagacttgtg
atcacatcagaagttattgacaatatctattctgttaaggcatattgttgggaatcagcg
atggagaagataattgaaagcttgagagaggaggaactgaaaatgacccggaggtcagcc
tatatgaggttcttcactagctctgccttcttcttttcagggttttttgtagtcttttta
tctgtgcttccctacacagtcatcaatggaatcgtcctccgaaaaatattcacaaccatt
tcattctgcattgtcctgcgtatgtcagtcacacggcaattccccactgctgtacagata
tggtatgattctttgggaatgataagaaaaatacaggatttcctacagactcaagaatat
aaagtgctggagtataacttaatgttcacaggcctagtcatggagaatgtaacagcattt
tgggaggagggatttcaggaattactggagaaagtacaactaaacaatgatgacagaaaa
acttccaatggtgagaaccacctcagttttagtcatctctgtctagtgggaaatcctgtg
ttgaaaaacatcaatttgaatataaagaaaggagagatgttggctattactggatctact
ggagcaggaaagacatcactcctgatgctgatactgggagaactggaagcgtcagaggga
attattaagcacagtggaagagtttcattctcctctcaaatttcttggattatgccgggt
actatcaaagaaaatatcatctttggtgtttcctatgatgagtacagatataagagtgtt
gtcaaagcttgccaactacaggaggacatcaccaagtttgcagaacaagacaacacagtt
cttggagaaggtggagtcacactcagtggaggtcaacgtgcaagaatttctttagcaaga
gcagtatataaagatgctgatttgtacctgttagattcccccttcggatatctagatgtt
ttaactgaagaacaaatatttgaaagttgtgtctgtaaattgatggccagcaaaactagg
attctggtcacatctaaaatggagcagttaaagaaagctgacaagatactcattttgcat
gagggcagcagctatttttatgggacgttttctgaactacaaagtctacgtccagacttc
agttccaaactcatggggtatgatacttttgaccagtttactgaggaaagaaggagttca
attctaactgagaccttacgcaggttctcagtggacgatgcctctaccacctggaacaaa
gccaaacagtcatttagacagactggagagtttggagaaaaaaggaagaactctattcta
agttcattcagctctgtgaagaaaatttccattgtgcaaaagactccattgtccatagaa
ggagaatctgatgacctccaagaaaggagactgtccctggttccagactctgaacatgga
gaggccgctctgcctcgcagcaacatgatcaccgccgggcccacgtttccaggcagaaga
agacagtctgttttggatcttatgacattcacacccagctcagtctccagcagtctccag
aggaccagagcttctattcgaaaaatatccttagcccctcggataagcttaaaggaagag
gatatatattcaaggcgattatcgcaagatagcacactgaacatcaccgaagaaattaat
gaagaagatttaaaggagtgtttttttgatgatatggtaaagatccccacggtgacaaca
tggaacacataccttcgatatttcacgctccacagaggcttatttgcagtgctgatttgg
tgcgtgctggtttttctggttgaggtggctgcttctttatttgtgttgtggttgcttaaa
aacaaccccgttaatggtggaaacaatggcactaaaattgccaatacctcctatgttgtg
gtcatcaccagttccagcttctattacattttttacatttacgtgggagtggctgacact
ttgcttgctctgagcctcttcagaggtttgcccctggtgcatacgttaatcacagcatca
aaaattttgcacaggaaaatgttacattctattcttcatgcccctatgtcaaccttcaac
aagctgaaagcaggtgggattcttaacagattctccaaagatatagcaattttggatgac
tttctgcctcttaccatatttgacttcatccagttgctgttcattgtggtcggagcaata
atagttgtctcggctttacaaccctacatcttcctagcaacggtgccagggctagcagtc
ttcattttactgagggcatacttccttcatacctcccaacagctcaaacaactggaatct
gaaggcaggagtccaattttcacgcaccttgttacaagcttaaaaggactgtggacactt
cgagccttccgacgccagacttactttgaaaccctattccacaaagctctgaatttgcac
actgccaactggtttatgtatctggcaaccttgcgctggttccagatgagaatagacatg
attttcgtcctcttcttcattgttgttaccttcatctccattttaacaacaggtgaagga
gaaggaacgactggtattattctaactttagctatgaatattatgagtactttgcaatgg
gctgtgaactcaagcattgatacagatagcttgatgcgatctgtgagcagagtctttaag
tttattgatatacaaacagaagaaagtatatgtaccaagataatgaaagaactacatagt
gaagactcacctaatgctttagtcattaagaatgaacatgtgaagaaatgtgatacctgg
ccctctggaggtgaaatggttgtcaaagaccttactgtgaaatatgtggatgatgggaat
gccatattagagaacatttctttttcaataagtcctggccagagggtggggctcttagga
agaactggctcaggaaaaagtactttgctgtcagcctttttacgaatgttgaacattaaa
ggcgaaatacagatcgatggtgtctcctggaactcaatgaccttacaagaatggagaaaa
gcttttggagtgataacacagaaagtatttatcttttctggaacattcagacaaaacttg
gatcccaatggaaaatggagagatgaagaaatatggaaagttgcagatcaggttggcctc
aagtctgtgatagagcagtttcctggacagctcaactttacccttgtggatgggggttat
gtgctaagccatggtcacaagcagttgatgtgcttggcccgatctgttctcagtaaggcc
aagatcatactgcttgatgagcctagtgccaatctagaccccataacataccaagtgatt
cgacgagttctaagacaagccttcgctggttgcacagtagtcctctgtgaacacaggata
gaagcaatgttggactgtcagcgatttttggtcatagagcagggcaatgtctggcagtat
gaatccctccaggcacttctgagcgagaagagtgtcttccagcgagcccttagctcctca
gaaaagatgaagctcttccacggccggcactccagcaagcagaagcctcggacacagatc
actgctgtgaaagaggagacggaggaagaagtgcaagagacccggctctag
DBGET
integrated database retrieval system
