Rattus norvegicus (rat): 24329
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Entry
24329 CDS
T01003
Symbol
Egfr
Name
(RefSeq) epidermal growth factor receptor isoform 2 precursor
KO
K04361
epidermal growth factor receptor [EC:
2.7.10.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno01522
Endocrine resistance
rno03272
Virion - Hepatitis viruses
rno04010
MAPK signaling pathway
rno04012
ErbB signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04020
Calcium signaling pathway
rno04066
HIF-1 signaling pathway
rno04068
FoxO signaling pathway
rno04072
Phospholipase D signaling pathway
rno04144
Endocytosis
rno04151
PI3K-Akt signaling pathway
rno04510
Focal adhesion
rno04520
Adherens junction
rno04540
Gap junction
rno04630
JAK-STAT signaling pathway
rno04810
Regulation of actin cytoskeleton
rno04912
GnRH signaling pathway
rno04915
Estrogen signaling pathway
rno04921
Oxytocin signaling pathway
rno04926
Relaxin signaling pathway
rno04928
Parathyroid hormone synthesis, secretion and action
rno04934
Cushing syndrome
rno05160
Hepatitis C
rno05163
Human cytomegalovirus infection
rno05165
Human papillomavirus infection
rno05171
Coronavirus disease - COVID-19
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05206
MicroRNAs in cancer
rno05207
Chemical carcinogenesis - receptor activation
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05210
Colorectal cancer
rno05212
Pancreatic cancer
rno05213
Endometrial cancer
rno05214
Glioma
rno05215
Prostate cancer
rno05218
Melanoma
rno05219
Bladder cancer
rno05223
Non-small cell lung cancer
rno05224
Breast cancer
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
rno05230
Central carbon metabolism in cancer
rno05231
Choline metabolism in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03272 Virion - Hepatitis viruses
24329 (Egfr)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
24329 (Egfr)
04012 ErbB signaling pathway
24329 (Egfr)
04014 Ras signaling pathway
24329 (Egfr)
04015 Rap1 signaling pathway
24329 (Egfr)
04630 JAK-STAT signaling pathway
24329 (Egfr)
04066 HIF-1 signaling pathway
24329 (Egfr)
04068 FoxO signaling pathway
24329 (Egfr)
04020 Calcium signaling pathway
24329 (Egfr)
04072 Phospholipase D signaling pathway
24329 (Egfr)
04151 PI3K-Akt signaling pathway
24329 (Egfr)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
24329 (Egfr)
09144 Cellular community - eukaryotes
04510 Focal adhesion
24329 (Egfr)
04520 Adherens junction
24329 (Egfr)
04540 Gap junction
24329 (Egfr)
09142 Cell motility
04810 Regulation of actin cytoskeleton
24329 (Egfr)
09150 Organismal Systems
09152 Endocrine system
04912 GnRH signaling pathway
24329 (Egfr)
04915 Estrogen signaling pathway
24329 (Egfr)
04921 Oxytocin signaling pathway
24329 (Egfr)
04926 Relaxin signaling pathway
24329 (Egfr)
04928 Parathyroid hormone synthesis, secretion and action
24329 (Egfr)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
24329 (Egfr)
05206 MicroRNAs in cancer
24329 (Egfr)
05205 Proteoglycans in cancer
24329 (Egfr)
05207 Chemical carcinogenesis - receptor activation
24329 (Egfr)
05208 Chemical carcinogenesis - reactive oxygen species
24329 (Egfr)
05230 Central carbon metabolism in cancer
24329 (Egfr)
05231 Choline metabolism in cancer
24329 (Egfr)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
24329 (Egfr)
09162 Cancer: specific types
05210 Colorectal cancer
24329 (Egfr)
05212 Pancreatic cancer
24329 (Egfr)
05225 Hepatocellular carcinoma
24329 (Egfr)
05226 Gastric cancer
24329 (Egfr)
05214 Glioma
24329 (Egfr)
05218 Melanoma
24329 (Egfr)
05219 Bladder cancer
24329 (Egfr)
05215 Prostate cancer
24329 (Egfr)
05213 Endometrial cancer
24329 (Egfr)
05224 Breast cancer
24329 (Egfr)
05223 Non-small cell lung cancer
24329 (Egfr)
09172 Infectious disease: viral
05160 Hepatitis C
24329 (Egfr)
05171 Coronavirus disease - COVID-19
24329 (Egfr)
05163 Human cytomegalovirus infection
24329 (Egfr)
05165 Human papillomavirus infection
24329 (Egfr)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
24329 (Egfr)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
24329 (Egfr)
01522 Endocrine resistance
24329 (Egfr)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
24329 (Egfr)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rno04147
]
24329 (Egfr)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
24329 (Egfr)
Protein kinases [BR:
rno01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
24329 (Egfr)
Exosome [BR:
rno04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
24329 (Egfr)
Exosomal proteins of pancreatic cancer cells
24329 (Egfr)
Exosomal proteins of bladder cancer cells
24329 (Egfr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Kinase-like
ABC1
Motif
Other DBs
NCBI-GeneID:
24329
NCBI-ProteinID:
NP_001380636
RGD:
2543
Ensembl:
ENSRNOG00000004332
LinkDB
All DBs
Position
14:95378626..95551358
Genome browser
AA seq
1195 aa
AA seq
DB search
MRPSGTARTKLLLLLAALCAAGGALEEKKVCQGTSNRLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNALYENTYALA
VLSNYGTNKTGLRELPMRNLQEILIGAVRFSNNPILCNMETIQWRDIVQDVFLSNMSMDV
QRHLTGCPKCDPSCPNGSCWGRGEENCQKLTKIICAQQCSRRCRGRSPSDCCHNQCAAGC
TGPRESDCLVCHRFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACGPDYYEVEEDGVSKCKKCDGPCRKVCNGIGIGEFKDTLSINATNIKHFK
YCTAISGDLHILPVAFKGDSFTRTPPLDPRELEILKTVKEITGFLLIQAWPENWTDLHAF
ENLEIIRGRTKQHGQFSLAVVGLNITSLGLRSLKEISDGDVIISGNRNLCYANTINWKKL
FGTPNQKTKIMNNRAEKDCKATNHVCNPLCSSEGCWGPEPTDCVSCQNVSRGRECVDKCN
ILEGEPREFVENSECIQCHPECLPQTMNITCTGRGPDNCIKCAHYVDGPHCVKTCPSGIM
GENNTLVWKFADANNVCHLCHANCTYGPKIPSIATGIVGGLLFIVVVALGIGLFMRRRHI
VRKRTLRRLLQERELVEPLTPSGEAPNQAHLRILKETEFKKIKVLGSGAFGTVYKGLWIP
EGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLM
PYGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKI
TDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSK
PYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELILEFSKMAR
DPQRYLVIQGDERMHLPSPTDSNFYRALMEEEDMEDVVDADEYLIPQQGFFNSPSTSRTP
LLSSLSANSNSSAVACINRNGSCRVKEDAFLQRYSSDPTSVLTEDNIDDTFLPVPEYINQ
SVPKRPAGSVQNPVYHNQPLHPAPGRDLHYQNPHSNAVSNPEYLNTAQPTCLSSGFDSSA
LWIQKGSHQMSLDNPDYQQDFFPKEAKPNGIFKGPTAENAEYLRVAPPSSEFIGA
NT seq
3588 nt
NT seq
+upstream
nt +downstream
nt
atgcgaccctcagggactgcgagaaccaagctactgctgctgctggctgcgctctgcgcc
gcaggtggggcgctggaggaaaagaaagtttgccaaggcacaagtaacaggctcacccaa
ctaggcacctttgaagaccactttctgagcctccagaggatgttcaacaactgtgaagtg
gtccttggaaacttggaaatcacctatgtgcaaaggaattatgacctttccttcttaaag
accattcaggaggtggctggctatgttctcattgccctgaacaccgtggagagaatccct
ttggagaacctgcagatcatcaggggaaatgctctctacgaaaacacctacgccttagcc
gtcctgtccaactatggaaccaacaaaactgggcttagggaactgcccatgcggaactta
caggaaattctgatcggtgctgtgcgatttagcaacaaccccatcctctgcaatatggag
accatccagtggagggacatcgtccaagatgtctttctgagcaacatgtcaatggacgta
cagcgccacctgaccggctgcccgaaatgtgatccgagctgtcccaatggaagctgctgg
ggaagaggagaggagaactgccagaaattgaccaaaatcatctgcgcccagcaatgttcc
cggcgttgtcgtggcaggtcccctagcgactgctgccacaaccagtgtgccgcagggtgt
acagggcccagagagagtgactgtctggtctgccacaggttccgagatgaagccacgtgc
aaagacacctgcccaccactcatgctgtacaaccccaccacgtaccagatggatgtcaac
cctgaggggaagtacagctttggtgccacctgtgtgaagaaatgccccagaaactacgtg
gtgacagatcacggctcgtgtgtccgggcctgtgggccagactactatgaagtagaagaa
gatggagtcagcaagtgtaaaaaatgtgatgggccctgccgcaaagtttgcaatggcata
ggcattggtgaatttaaagacacactctccataaatgctacaaacatcaaacacttcaag
tactgcactgccatcagtggggacctccacatcctgccagtggcctttaagggggattct
ttcacccgcactcctcctctagacccacgggaactagaaattctcaaaactgtgaaggaa
ataacagggtttttgctgattcaggcttggcctgaaaactggactgacctccatgctttt
gagaacctagaaataattcgtggcagaacaaagcaacatggtcagttttctctggcggtt
gtcggcctgaacataacatcgctggggttgcgttccctcaaggagatcagtgatggggat
gtgattatttctgggaaccgaaatttgtgctacgcaaacactataaactggaaaaaactc
ttcgggacgcccaatcaaaagaccaaaatcatgaacaacagagctgaaaaggactgcaag
gccacgaaccacgtctgtaatcctttatgctcctcggaaggctgctggggccctgagccc
acggactgtgtctcctgccagaatgtgagcagaggcagggagtgcgtggacaagtgcaac
atcctggagggggaaccgagggagtttgtggaaaattctgaatgcatccagtgccatcca
gaatgtctgccccagaccatgaacatcacctgtacaggccgggggccagacaactgcatc
aagtgtgcccactatgttgatggtccccactgtgtcaagacctgcccttcgggcatcatg
ggggagaacaacaccctggtctggaagtttgcagatgccaataacgtctgccacctctgc
catgcaaactgtacctatgggccaaagatcccatccatcgccactgggattgtgggtggc
ctcctcttcatagtagtggtggcccttgggatcggcctcttcatgcgaaggcgtcacatt
gtccgaaaacgtacactacgccgcctgcttcaagagagagagctcgtggaacctctcaca
cccagcggagaagctccgaaccaagcccacttgaggatattaaaggaaacagaattcaaa
aagatcaaagttctgggttcaggagcatttggcacagtgtataagggtctctggatccca
gaaggcgagaaagtgaaaatccctgtggccatcaaggagttaagagaagccacatctccc
aaagccaacaaggaaatccttgatgaagcctacgtgatggccagtgtggacaaccctcat
gtatgccgcctcctgggcatctgtctgacctccactgtccagctcattacacaactcatg
ccctatggttgcctcctggactatgtccgagaacataaggacaacattggctcccagtac
ctactcaactggtgtgtgcagattgcaaagggcatgaactacctggaagaccggcgtttg
gtacaccgtgacttggcagccaggaatgtactggtaaagacaccacagcatgtcaagatc
acagattttggactggccaaactgcttggtgctgaggagaaagaataccatgcagagggg
ggcaaagtgcctatcaagtggatggctttggaatcaattttacaccgaatttatacacac
caaagcgacgtctggagctatggagtcaccgtgtgggaactgatgacctttgggtccaag
ccttatgatgggatccctgcaagtgagatctcatccatcctagagaaaggagagcgcctt
ccacagccacctatctgcaccatcgacgtctacatgatcatggtcaagtgctggatgata
gatgctgatagccgcccaaagttccgagagttgattctcgaattctccaaaatggccaga
gacccacagcgctaccttgttatccagggggatgaaaggatgcatttgccgagccctaca
gactccaacttttaccgagccctgatggaggaggaggacatggaagacgtagttgatgct
gatgaatacctcatcccacagcaaggcttcttcaacagcccatccacgtcacggactcca
ctcttgagctctctgagtgcaaatagcaacagttccgctgtggcttgcattaatagaaat
gggagctgccgtgtcaaagaagacgccttcttgcaacggtatagctccgatcccaccagc
gtcctgacagaggacaacatagatgacacattccttcccgtgcctgaatatataaaccaa
tctgttcccaagaggccggctggctctgtgcagaacccagtctatcacaatcagcccctg
catccagctcctggaagagacctgcattatcaaaatccccatagcaatgcggtgagcaac
cctgagtatctcaacactgcccagccgacctgcctcagtagtgggtttgacagctctgcc
ctctggatccagaaaggcagccaccaaatgagcctggacaaccctgactaccagcaggac
ttctttcccaaagaagccaagccgaatggcatctttaagggccccacagctgaaaatgca
gagtacctgcgggtggcaccgccaagcagtgagtttattggagcatga
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integrated database retrieval system
