Rattus norvegicus (rat): 24337
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Entry
24337 CDS
T01003
Symbol
Erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 precursor
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno01522
Endocrine resistance
rno01524
Platinum drug resistance
rno04010
MAPK signaling pathway
rno04012
ErbB signaling pathway
rno04020
Calcium signaling pathway
rno04066
HIF-1 signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04510
Focal adhesion
rno04520
Adherens junction
rno04530
Tight junction
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05206
MicroRNAs in cancer
rno05212
Pancreatic cancer
rno05213
Endometrial cancer
rno05215
Prostate cancer
rno05219
Bladder cancer
rno05223
Non-small cell lung cancer
rno05224
Breast cancer
rno05226
Gastric cancer
rno05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
24337 (Erbb2)
04012 ErbB signaling pathway
24337 (Erbb2)
04066 HIF-1 signaling pathway
24337 (Erbb2)
04020 Calcium signaling pathway
24337 (Erbb2)
04151 PI3K-Akt signaling pathway
24337 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
24337 (Erbb2)
04520 Adherens junction
24337 (Erbb2)
04530 Tight junction
24337 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
24337 (Erbb2)
05206 MicroRNAs in cancer
24337 (Erbb2)
05205 Proteoglycans in cancer
24337 (Erbb2)
05230 Central carbon metabolism in cancer
24337 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
24337 (Erbb2)
05226 Gastric cancer
24337 (Erbb2)
05219 Bladder cancer
24337 (Erbb2)
05215 Prostate cancer
24337 (Erbb2)
05213 Endometrial cancer
24337 (Erbb2)
05224 Breast cancer
24337 (Erbb2)
05223 Non-small cell lung cancer
24337 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
24337 (Erbb2)
01524 Platinum drug resistance
24337 (Erbb2)
01522 Endocrine resistance
24337 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
24337 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rno04147
]
24337 (Erbb2)
04090 CD molecules [BR:
rno04090
]
24337 (Erbb2)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
24337 (Erbb2)
Protein kinases [BR:
rno01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
24337 (Erbb2)
Exosome [BR:
rno04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
24337 (Erbb2)
CD molecules [BR:
rno04090
]
Proteins
24337 (Erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
CD34_antigen
DUF5849
EphA2_TM
PDGLE
Motif
Other DBs
NCBI-GeneID:
24337
NCBI-ProteinID:
NP_058699
RGD:
2561
Ensembl:
ENSRNOG00000006450
UniProt:
Q8K3F9
LinkDB
All DBs
Position
10:83907491..83931365
Genome browser
AA seq
1259 aa
AA seq
DB search
MIIMELAAWCRWGFLLALLPPGIAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQ
GNLELTYVPANASLSFLQDIQEVQGYMLIAHNQVKRVPLQRLRIVRGTQLFEDKYALAVL
DNRDPQDNVAASTPGRTPEGLRELQLRSLTEILKGGVLIRGNPQLCYQDMVLWKDVFRKN
NQLAPVDIDTNRSRACPPCAPACKDNHCWGESPEDCQILTGTICTSGCARCKGRLPTDCC
HEQCAAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMHNPEGRYTFGASCV
TTCPYNYLSTEVGSCTLVCPPNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLRGARAI
TSDNVQEFDGCKKIFGSLAFLPESFDGDPSSGIAPLRPEQLQVFETLEEITGYLYISAWP
DSLRDLSVFQNLRIIRGRILHDGAYSLTLQGLGIHSLGLRSLRELGSGLALIHRNAHLCF
VHTVPWDQLFRNPHQALLHSGNRPEEDCGLEGLVCNSLCAHGHCWGPGPTQCVNCSHFLR
GQECVEECRVWKGLPREYVSDKRCLPCHPECQPQNSSETCFGSEADQCAACAHYKDSSSC
VARCPSGVKPDLSYMPIWKYPDEEGICQPCPINCTHSCVDLDERGCPAEQRASPVTFIIA
TVVGVLLFLILVVVVGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILK
ETELRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAG
VGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYL
EDVRLVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILR
RRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMV
KCWMIDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPSSPMDSTFYRSLLEDDDMGD
LVDAEEYLVPQQGFFSPDPTPGTGSTAHRRHRSSSTRSGGGELTLGLEPSEEGPPRSPLA
PSEGAGSDVFDGDLAMGVTKGLQSLSPHDLSPLQRYSEDPTLPLPPETDGYVAPLACSPQ
PEYVNQSEVQPQPPLTPEGPLPPVRPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEY
LVPREGTASPPHPSPAFSPAFDNLYYWDQNSSEQGPPPSNFEGTPTAENPEYLGLDVPV
NT seq
3780 nt
NT seq
+upstream
nt +downstream
nt
atgatcatcatggagctggcggcctggtgccgctgggggttcctcctcgccctcctgccc
cccggaatcgcgggcacccaagtgtgtaccggcacagacatgaagttgcggctccctgcc
agtcctgagacccacctggacatgctccgccacctgtaccagggctgtcaggtagtgcag
ggcaacttggagcttacctacgtgcctgccaatgccagcctctcattcctgcaggacatc
caggaagttcagggttacatgctcatcgctcacaaccaggtgaagcgcgtcccactgcaa
aggctgcgcatcgtgagagggacccagctctttgaggacaagtatgccctggctgtgcta
gacaaccgagatcctcaggacaatgtcgccgcctccaccccaggcagaaccccagagggg
ctgcgggagctgcagcttcgaagtctcacagagatcctgaagggaggagttttgatccgt
gggaaccctcagctctgctaccaggacatggttttgtggaaggacgtcttccgcaagaat
aaccaactggctcctgtcgatatagacaccaatcgttcccgggcctgtccaccttgtgcc
cccgcctgcaaagacaatcactgttggggtgagagtccggaagactgtcagatcttgact
ggcaccatctgtaccagtggttgtgcccggtgcaagggccggctgcccactgactgctgc
catgagcagtgtgccgcaggctgcacgggccccaagcattctgactgcctggcctgcctc
cacttcaatcatagtggtatctgtgagctgcactgcccagccctcgtcacctacaacaca
gacacctttgagtccatgcacaaccctgagggtcgctacacctttggtgccagctgcgtg
accacctgcccctacaactacctgtctacggaagtgggatcctgcactctggtgtgtccc
ccgaataaccaagaggtcacagctgaggacggaacacagcgttgtgagaaatgcagcaag
ccctgtgctcgagtgtgctatggtctgggcatggagcaccttcgaggggcgagggccatc
accagtgacaatgtccaggagtttgatggctgcaagaagatctttgggagcctggcattt
ttgccggagagctttgatggggacccctcctccggcattgctccgctgaggcctgagcag
ctccaagtgttcgaaaccctggaggagatcacaggttacctgtacatctcagcatggcca
gacagtctccgtgacctcagtgtcttccagaaccttcgaatcattcggggacggattctc
cacgatggcgcgtactcattgacactgcaaggcctggggatccactcgctggggctgcgc
tcactgcgggagctgggcagtggattggctctgattcaccgcaacgcccatctctgcttt
gtacacactgtaccttgggaccagctcttccggaacccacatcaggccctgctccacagt
gggaaccggccggaagaggattgtggtctcgagggcttggtctgtaactcactgtgtgcc
cacgggcactgctgggggccagggcccacccagtgtgtcaactgcagtcatttccttcgg
ggccaggagtgtgtggaggagtgccgagtatggaaggggctcccccgggagtatgtgagt
gacaagcgctgtctgccgtgtcaccccgagtgtcagcctcaaaacagctcagagacctgc
tttggatcggaggctgatcagtgtgcagcctgcgcccactacaaggactcgtcctcctgt
gtggctcgctgccccagtggtgtgaaaccggacctctcctacatgcccatctggaagtac
ccggatgaggagggcatatgccagccgtgccccatcaactgcacccactcctgtgtggat
ctggatgaacgaggctgcccagcagagcagagagccagcccggtgacattcatcattgca
actgtagtgggcgtcctgctgttcctgatcttagtggtggtcgttggaatcctaatcaaa
cgaaggagacagaagatccggaagtatacgatgcgtaggctgctgcaggaaactgagtta
gtggagccgctgacgcccagcggagcaatgcccaaccaggctcagatgcggatcctaaaa
gagacggagctaaggaaggtgaaggtgcttggatcaggagcttttggcactgtctacaag
ggcatctggatcccagatggggagaatgtgaaaatccccgtggctatcaaggtgttgaga
gaaaacacatctcctaaagccaacaaagaaattctagatgaagcgtatgtgatggctggt
gtgggttctccgtatgtgtcccgcctcctgggcatctgcctgacatccacagtacagctg
gtgacacagcttatgccctacggctgccttctggaccatgtccgagaacaccgaggtcgc
ctaggctcccaggacctgctcaactggtgtgttcagattgccaaggggatgagctacctg
gaggacgtgcggcttgtacacagggacctggctgcccggaatgtgctagtcaagagtccc
aaccacgtcaagattacagatttcgggctggctcggctgctggacattgatgagacagag
taccatgcagatgggggcaaggtgcccatcaaatggatggcattggaatctattctcaga
cgccggttcacccatcagagtgatgtgtggagctatggagtgactgtgtgggagctgatg
acttttggggccaaaccttacgatggaatcccagcccgggagatccctgatttgctggag
aagggagaacgcctacctcagcctccaatctgcaccattgatgtctacatgattatggtc
aaatgttggatgattgactctgaatgtcgcccgagattccgggagttggtgtcagaattt
tcacgtatggcgagggacccccagcgttttgtggtcatccagaacgaggacttgggccca
tccagccccatggacagtaccttctaccgttcactgctggaagatgatgacatgggtgac
ctggtagacgctgaagagtatctggtgccccagcagggattcttctccccggaccctacc
ccaggcactgggagcacagcccatagaaggcaccgcagctcgtccaccaggagtggaggt
ggtgagctgacactgggcctggagccctcggaagaagggccccccagatctccactggct
ccctcggaaggggctggctccgatgtgtttgatggtgacctggcaatgggggtaaccaaa
gggctgcagagcctctctccacatgacctcagccctctacagcggtacagcgaggacccc
acattacctctgccccccgagactgatggctatgttgctcccctggcctgcagcccccag
cccgagtatgtgaaccaatcagaggttcagcctcagcctcctttaaccccagagggtcct
ctgcctcctgtccggcctgctggtgctactctagaaagacccaagactctctctcctggg
aagaatggggttgtcaaagacgtttttgccttcgggggtgctgtggagaaccctgaatac
ttagtaccgagagaaggcactgcctctccgccccacccttctcctgccttcagcccagcc
tttgacaacctctattactgggaccagaactcatcggagcaggggcctccaccaagtaac
tttgaagggacccccactgcagagaaccctgagtacctaggcctggatgtacctgtatga
DBGET
integrated database retrieval system
