Rattus norvegicus (rat): 24418
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Entry
24418 CDS
T01003
Symbol
Grm5
Name
(RefSeq) metabotropic glutamate receptor 5 precursor
KO
K04604
metabotropic glutamate receptor 5
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04020
Calcium signaling pathway
rno04072
Phospholipase D signaling pathway
rno04080
Neuroactive ligand-receptor interaction
rno04082
Neuroactive ligand signaling
rno04540
Gap junction
rno04720
Long-term potentiation
rno04723
Retrograde endocannabinoid signaling
rno04724
Glutamatergic synapse
rno05010
Alzheimer disease
rno05016
Huntington disease
rno05022
Pathways of neurodegeneration - multiple diseases
rno05215
Prostate cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
24418 (Grm5)
04072 Phospholipase D signaling pathway
24418 (Grm5)
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
24418 (Grm5)
04082 Neuroactive ligand signaling
24418 (Grm5)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
24418 (Grm5)
09150 Organismal Systems
09156 Nervous system
04724 Glutamatergic synapse
24418 (Grm5)
04720 Long-term potentiation
24418 (Grm5)
04723 Retrograde endocannabinoid signaling
24418 (Grm5)
09160 Human Diseases
09162 Cancer: specific types
05215 Prostate cancer
24418 (Grm5)
09164 Neurodegenerative disease
05010 Alzheimer disease
24418 (Grm5)
05016 Huntington disease
24418 (Grm5)
05022 Pathways of neurodegeneration - multiple diseases
24418 (Grm5)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04030 G protein-coupled receptors [BR:
rno04030
]
24418 (Grm5)
G protein-coupled receptors [BR:
rno04030
]
Metabotropic glutamate receptor family
Glutamate (metabotropic)
24418 (Grm5)
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
ANF_receptor
7tm_3
GluR_Homer-bdg
NCD3G
Peripla_BP_6
DUF5438
Motif
Other DBs
NCBI-GeneID:
24418
NCBI-ProteinID:
NP_058708
RGD:
2746
Ensembl:
ENSRNOG00000016429
UniProt:
P31424
A6I5Y9
Structure
PDB
PDBj
LinkDB
All DBs
Position
1:150722711..151297585
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AA seq
1171 aa
AA seq
DB search
MVLLLILSVLLLKEDVRGSAQSSERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAV
REQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVALEQSIEFIRDSLISS
EEEEGLVRCVDGSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSD
KTLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKEGIC
IAHSYKIYSNAGEQSFDKLLKKLRSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLL
LGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKLRPETNLRNPWFQEFWQH
RFQCRLEGFAQENSKYNKTCNSSLTLRTHHVQDSKMGFVINAIYSMAYGLHNMQMSLCPG
YAGLCDAMKPIDGRKLLDSLMKTNFTGVSGDMILFDENGDSPGRYEIMNFKEMGKDYFDY
INVGSWDNGELKMDDDEVWSKKNNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENE
YVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPEPIAAVVFACLGLLATLFVTVIF
IIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSYSA
LVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMH
DYPSIREVYLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTT
CIIWLAFVPIYFGSNYKIITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTST
VVRMHVGDGKSSSAASRSSSLVNLWKRRGSSGETLSSNGKSVTWAQNEKSTRGQHLWQRL
SVHINKKENPNQTAVIKPFPKSTENRGPGAAAGGGSGPGVAGAGNAGCTATGGPEPPDAG
PKALYDVAEAEESFPAAARPRSPSPISTLSHLAGSAGRTDDDAPSLHSETAARSSSSQGS
LMEQISSVVTRFTANISELNSMMLSTAATPGPPGTPICSSYLIPKEIQLPTTMTTFAEIQ
PLPAIEVTGGAQGATGVSPAQETPTGAESAPGKPDLEELVALTPPSPFRDSVDSGSTTPN
SPVSESALCIPSSPKYDTLIIRDYTQSSSSL
NT seq
3516 nt
NT seq
+upstream
nt +downstream
nt
atggtccttctgttgatcctgtcagtcctacttctgaaagaagatgtacgagggagtgca
cagtccagtgagaggagggtggtggctcacatgccaggtgacatcattattggcgctctc
ttctctgtccaccaccaaccaactgtggacaaagttcatgagaggaagtgtggtgcagtt
cgtgagcaatatgggattcagagagtggaggccatgctgcataccttggaaaggatcaac
tcagatcccacactcttgcccaacatcacacttggctgtgagatcagagattcctgctgg
cattccgctgtggccctagaacaaagcattgagtttataagggattccctcatctcttca
gaagaggaggaaggtttggtacgctgtgtagatggatcttcttccttccgctccaagaaa
cccatagtgggagtcattgggcctggctctagttctgtggccattcaagtccagaactta
ctccagcttttcaacataccacagattgcttactctgcaaccagcatggatttgagtgac
aagactctattcaagtacttcatgagggttgtaccttccgatgcccagcaagctcgagcc
atggtagacatagtgaagagatacaactggacttatgtctcagctgtgcacacagaaggc
aactatggagaaagtgggatggaggctttcaaagatatgtcagcgaaggaagggatttgc
atcgcccactcttacaaaatttacagcaatgctggggaacagagctttgacaagctgttg
aaaaaactcagaagtcatttacctaaagcccgggtggtagcttgcttctgtgaaggcatg
acagttcgaggtctgctcatggccatgagacgcttgggtctagcaggggagtttctactt
ctgggcagtgatggctgggccgacaggtatgacgtgacagatggatatcagcgagaagct
gtcggtggaattacaatcaagcttcagtctcctgatgtcaagtggtttgatgattattat
ctgaaactccggccagaaacaaacctcagaaacccttggtttcaagaattttggcagcat
cgttttcagtgccggctggaagggtttgcacaggagaacagcaagtacaacaagacttgc
aacagttctctgactctgagaacacatcatgttcaagattccaaaatgggatttgtgata
aatgcaatctattctatggcttatggactccacaatatgcagatgtccctgtgtccaggc
tatgcaggcctctgtgatgcgatgaagccaattgatggacggaaacttttggattccctg
atgaaaaccaattttactggagtttctggagatatgatcctgtttgatgaaaatggagac
tctccaggaaggtatgaaataatgaatttcaaggaaatgggaaaagattattttgattac
atcaatgttggaagttgggacaatggggaattaaaaatggatgatgacgaagtgtggtcc
aagaaaaataacatcatcagatctgtgtgcagtgaaccatgtgagaaaggccaaataaag
gtgatccggaagggagaagtcagctgttgttggacctgcacaccttgtaaagagaatgag
tatgtgtttgatgagtacacctgcaaggcatgccaactgggctcctggcccactgacgac
ctgacaggctgtgacttgatcccagtccagtatcttcgctggggtgaccctgagccgatt
gcagctgtggtgtttgcctgcctcggtctgctagccaccttattcgttactgtaatcttc
atcatttatcgggacactccggtggtcaagtcctccagcagggagctctgctacattatc
cttgctggcatctgcctgggatacttatgtaccttttgcctcattgcaaagcccaagcag
atttactgctatcttcagagaattggcattggactctctccagccatgagctactcagcc
cttgtaaccaagaccaaccgtattgcaaggattctagctggaagcaagaagaaaatctgt
accaagaagcccagattcatgagcgcctgtgctcagttagtgatcgctttcattctcatc
tgtattcagctgggcattatcgtggccctctttatcatggagcctccggatataatgcat
gactatccaagcatccgagaagtctacttgatttgtaacaccaccaacctaggggttgtt
actcctcttggatacaatggattattgattttgagttgcacgttctatgcgtttaagacc
agaaatgttccagccaactttaatgaggccaaatatattgctttcaccatgtacacaacc
tgcatcatatggctggccttcgtgcctatctactttggcagcaactacaaaatcatcacc
atgtgtttttcagtcagcctcagtgccacagtggccctgggttgcatgtttgtcccgaag
gtgtacatcatcctagccaaaccggagagaaatgtgcgcagcgccttcacaacctctaca
gtggtacgcatgcatgtaggagacggcaaatcatcgtccgctgccagcagatccagcagc
ctagtcaacctgtggaagaggaggggctcctctggggaaaccctaagctccaacggaaaa
tctgtgacttgggcccagaatgagaagagtacccgggggcaacatttgtggcagcgactg
tctgtccacatcaacaagaaggagaaccccaaccaaacggcggtcatcaaaccctttccc
aagagcacagagaaccgggggcctggtgcagcggcaggtggtggctcgggtcccggtgta
gctggtgctggtaacgcaggatgcacagcaacaggtggcccggagccaccggacgccggt
cccaaagcgctttatgatgtggcggaggcagaggagagcttccccgcggctgccaggccg
cgctcgccatcgcccatcagcacgttgagccacctcgcaggctcggcgggccgcacagat
gatgatgcgccgtcgctgcactctgagacagctgctcgcagcagctcgtcccagggctcg
ctcatggagcagatcagcagcgtagtgacgcgcttcacagccaacatctccgagctcaac
tccatgatgttgtccaccgcggccacgccggggccccctggtactccaatctgctcctcc
tacctgatccccaaagagattcagctgcccacgaccatgacgaccttcgcagagatccag
ccgctgccggccatcgaggtgaccggaggagctcagggggcgacaggggtatcacctgcc
caggagacgcccacaggagctgaatccgccccgggcaaaccagatctggaggagcttgtg
gccctcactccaccatcgcccttcagggactcggtggactcggggagcaccaccccaaac
tctccagtctcagaatcggccctctgcatcccatcctctcccaaatatgacactctcatc
atcagagattacacgcagagttcttcatcgttgtga
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