Rattus norvegicus (rat): 24446
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Entry
24446 CDS
T01003
Symbol
Hgf
Name
(RefSeq) hepatocyte growth factor preproprotein
KO
K05460
hepatocyte growth factor
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno04010
MAPK signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04020
Calcium signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04510
Focal adhesion
rno05144
Malaria
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05208
Chemical carcinogenesis - reactive oxygen species
rno05211
Renal cell carcinoma
rno05218
Melanoma
rno05223
Non-small cell lung cancer
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
24446 (Hgf)
04014 Ras signaling pathway
24446 (Hgf)
04015 Rap1 signaling pathway
24446 (Hgf)
04020 Calcium signaling pathway
24446 (Hgf)
04151 PI3K-Akt signaling pathway
24446 (Hgf)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
24446 (Hgf)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
24446 (Hgf)
05205 Proteoglycans in cancer
24446 (Hgf)
05208 Chemical carcinogenesis - reactive oxygen species
24446 (Hgf)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
24446 (Hgf)
05226 Gastric cancer
24446 (Hgf)
05218 Melanoma
24446 (Hgf)
05211 Renal cell carcinoma
24446 (Hgf)
05223 Non-small cell lung cancer
24446 (Hgf)
09174 Infectious disease: parasitic
05144 Malaria
24446 (Hgf)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
24446 (Hgf)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
rno04052
]
24446 (Hgf)
00536 Glycosaminoglycan binding proteins [BR:
rno00536
]
24446 (Hgf)
Cytokines and neuropeptides [BR:
rno04052
]
Cytokines
Growth factors (RTK binding)
24446 (Hgf)
Glycosaminoglycan binding proteins [BR:
rno00536
]
Heparan sulfate / Heparin
Growth factors/receptors
24446 (Hgf)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Kringle
Trypsin
PAN_1
DUF1986
Motif
Other DBs
NCBI-GeneID:
24446
NCBI-ProteinID:
NP_058713
RGD:
2794
Ensembl:
ENSRNOG00000007027
UniProt:
P17945
A6K5E8
LinkDB
All DBs
Position
4:complement(19628902..19700467)
Genome browser
AA seq
728 aa
AA seq
DB search
MMWGTKLLPVLLLQHVLLHLLLLPVTIPYAEGQKKRRNTLHEFKKSAKTTLTKEDPLVKI
KTKKVNSADECANRCIRNKGFPFTCKAFVFDKSRKRCYWYPFNSMSSGVKKGFGHEFDLY
ENKDYIRNCIIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKDLQENYCRN
PRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECMTCNGESYRGPMDHTESGKTCQRWDQQT
PHRHKFLPERYPDKGFDDNYCRNPDGKPRPWCYTLDPDTPWEYCAIKMCAHSAVNETDVP
METTECIKGQGEGYRGTTNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDG
AESPWCFTTDPNIRVGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNM
EDLHRHIFWEPDASKLTKNYCRNPDDDAHGPWCYTGNPLVPWDYCPISRCEGDTTPTIVN
LDHPVISCAKTKQLRVVNGIPTQTTVGWMVSLKYRNKHICGGSLIKESWVLTARQCFPAR
NKDLKDYEAWLGIHDVHERGEEKRKQILNISQLVYGPEGSDLVLLKLARPAILDNFVSTI
DLPSYGCTIPEKTTCSIYGWGYTGLINADGLLRVAHLYIMGNEKCSQHHQGKVTLNESEL
CAGAEKIGSGPCEGDYGGPLICEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWIH
KVILTYKL
NT seq
2187 nt
NT seq
+upstream
nt +downstream
nt
atgatgtgggggaccaaacttctgccggtcctgttgctgcagcatgtcctgctgcacctc
ctcctgcttcctgtcaccatcccctatgcagaaggacagaagaagagaagaaatactctt
catgaattcaaaaagtcagcaaaaactactcttaccaaggaagacccattagtgaagatt
aaaaccaaaaaagtgaactctgcagatgagtgtgccaacaggtgcatcagaaacaagggc
tttccattcacttgcaaggcctttgtttttgataagtcgagaaaacgatgctactggtat
cctttcaatagtatgtcaagtggagtgaaaaaagggtttggccatgaatttgacctctat
gaaaacaaagactatattagaaattgcatcattggtaaaggaggcagctataaggggaca
gtatccatcactaagagtggcatcaagtgccagccttggaattccatgatcccccatgaa
cacagctttttgccttcgagctatcgcggtaaagacctacaggaaaactactgtcgaaat
cctcgaggggaagaagggggaccctggtgtttcacaagcaatccagaggtacgctacgaa
gtctgtgacattcctcagtgttcagaagttgaatgcatgacctgcaacggtgaaagctac
agaggtcccatggatcacacagaatcaggcaagacatgtcagcgctgggatcagcagaca
ccacaccggcacaaattcttgccggaaagatatcccgacaagggctttgatgataattat
tgccgcaatcccgatggcaagccgaggccatggtgctacactcttgaccctgacacccct
tgggagtattgtgcaattaaaatgtgcgctcacagtgctgtgaatgagactgatgttccc
atggaaacaactgaatgtataaaaggccaaggagaaggttacaggggaaccaccaatacc
atttggaatggaattccgtgtcagcgttgggattcgcagtacccccacaagcatgacatc
actcccgagaacttcaaatgcaaggaccttagagaaaattattgccgcaatccggatggg
gctgaatcaccatggtgttttaccactgatccaaacatccgagttggttactgctctcaa
attcccaaatgtgacgtgtcaagtggacaagattgttatcgtggcaatgggaaaaactac
atgggcaacttatccaaaacaaggtctggactcacatgttccatgtgggacaagaatatg
gaggatttacaccgtcatatcttctgggagccagacgctagcaagttgactaagaattac
tgccggaaccccgatgacgacgcccatggaccttggtgctacacagggaatcctctcgtt
ccttgggattattgccctatttcccgttgtgaaggagatactacacctacaattgtcaat
ttggaccatcctgtaatatcctgtgccaaaacaaaacaactgcgagttgtaaatggcatt
ccaacacaaacaacagtagggtggatggttagtttgaaatacaggaataaacacatctgt
gggggatcattgataaaggaaagttgggttcttactgcaaggcaatgttttccagctaga
aacaaagacttgaaagactatgaagcttggcttggaatccatgatgtccatgagagaggc
gaggagaaacgcaaacagatcttaaacatttcccagctagtctatggacctgaaggctca
gatttggttttactgaagcttgctcgccctgcaatcctggataactttgtcagtacaatt
gatttacctagttatggctgtacaatccctgaaaagactacttgcagtatttacggctgg
ggctacactggattgatcaacgcagatggtttattacgagtagctcatctgtatattatg
gggaatgagaaatgcagtcagcaccatcaaggcaaggtgactttgaatgagtctgaatta
tgtgctggggctgaaaagattggatcaggaccttgtgagggagattatggtggcccactc
atttgtgaacaacacaaaatgagaatggttcttggtgtcattgttcctggtcgtggatgt
gccatcccaaatcgtcctggtatttttgttcgagtagcatattatgcaaaatggatacac
aaagtaattttgacatacaagttgtaa
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