Rattus norvegicus (rat): 24627
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Entry
24627 CDS
T01003
Symbol
Pde4d
Name
(RefSeq) 3',5'-cyclic-AMP phosphodiesterase 4D isoform 1
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00230
Purine metabolism
rno01100
Metabolic pathways
rno04024
cAMP signaling pathway
rno04928
Parathyroid hormone synthesis, secretion and action
rno05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
24627 (Pde4d)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
24627 (Pde4d)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
24627 (Pde4d)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
24627 (Pde4d)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
24627 (Pde4d)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
24627
NCBI-ProteinID:
NP_001106799
RGD:
3281
Ensembl:
ENSRNOG00000042536
UniProt:
P14270
A0A8I6ABM9
A6I5L1
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All DBs
Position
2:41748337..43262567
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AA seq
803 aa
AA seq
DB search
MEAEGSSVPARAGSDEGSDSSGGAALKAPKHLWRHEQHHQYPLRQPQFRLLHPHHHLPPP
PPPSPQPQLQPPPPPPLPPPPPPPGATRGRYASSGASRVRHRGYSDTERYLYCRAMDRTS
YAVETGHRPGLKKSRMSWPSSFQGLRRFDVDNGTSAGRSPLDPMTSPGSGLILQANFVHS
QRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFAALTN
LQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVSEMAS
NKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPMSQIS
GVKKLMHSSSLTNSCIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLTVIMH
TIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTPALEA
VFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQE
ENCDIFQNLTKKQRQSLRKMAIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLLLDNY
SDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCDKHNA
SVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPDDQED
GRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLDEQVE
EEAVAEEESQPQTGVADDCCPDT
NT seq
2412 nt
NT seq
+upstream
nt +downstream
nt
atggaggcagagggcagcagcgtgccggcccgggcgggcagcgacgagggcagcgacagc
tctggaggggccgcgctcaaagcccccaagcatctctggaggcacgagcagcaccaccag
tacccgctccggcagccccagttccgcctcttgcacccccatcaccacctgcccccgccg
ccgccaccctcgccccagccccagctgcagccaccaccaccgcccccactgccaccaccc
ccgccaccgcccggagctacccgtggtcgctacgcctcaagcggggctagccgcgtccgg
caccgcggctactcggacacggagcgctacctgtactgccgtgccatggaccgcacctcc
tacgcggtggagactggtcaccggccaggcctgaagaaatctaggatgtcctggccctcg
tctttccagggactcagacgtttcgatgtggacaatggcacatcagcgggacggagtccc
ttggatcccatgaccagcccagggtctgggctaattctccaagcaaactttgtgcacagt
caacgccgggagtccttcctgtatcgatcagacagcgattatgacctctctccaaagtct
atgtccaggaactcctcgattgccagtgatatacatggagatgacttgattgtgactcca
tttgctcaggtcttggccagccttcgaactgtaagaaacaactttgctgcattaactaat
ttgcaagatcgcgcacccagcaaaagatcacccatgtgcaaccaaccatccatcaacaaa
gccaccatcacagaggaggcctaccagaaactggccagcgagaccctggaggagctggac
tggtgtctggaccagctagagaccctgcagaccaggcactccgtcagtgagatggcctcc
aacaagttcaagaggatgcttaatcgggagctcacccacctctctgaaatgagtcggtct
ggcaaccaggtgtcggagtacatatcaaacacgttcttagataagcaacatgaagtagaa
attccctctccgactcagaaggaaaaagagaagaagaaaaggccgatgtcacagatcagt
ggggtcaagaagttgatgcacagctccagcctgaccaattcctgcatcccaagatttggg
gttaaaacagagcaggaagatgtcctggccaaggaactagaagacgtgaacaagtggggc
ctccacgttttccgaatagcggagctgtctggcaaccggcctctgactgttatcatgcac
accatttttcaggaacgagatttgttaaaaacgtttaaaatcccagtggacactttgatt
acgtatcttatgactctagaagaccattaccatgctgacgtggcctatcacaacaacatc
catgctgcagatgtcgtccagtcaactcatgtgctgctctctacacccgctttggaggct
gttttcactgacttggagattctcgcggccatttttgccagtgcaatacatgatgtggat
catcctggtgtgtcaaatcaatttctgatcaatacaaactcggaacttgccttgatgtac
aacgactcctccgtcttagagaatcatcatttggctgtgggctttaagttgctccaggaa
gaaaactgtgacattttccagaatctgaccaaaaagcaaagacaatctttaaggaaaatg
gccattgacattgtactagcgacagacatgtcaaagcacatgaatctgctggctgatctg
aaaacaatggttgaaacgaagaaggtgacgagctctggcgtcctcctccttgataactat
tctgacaggatccaggtcctccagaatatggtgcactgtgcagacctgagcaaccccaca
aagccactccagctctaccgccagtggacggaccggataatggaggagttcttccgtcag
ggggaccgggagcgtgagcgtggcatggagataagtcccatgtgtgacaagcacaacgcc
tctgtggaaaaatcacaggtgggcttcatagactatattgttcatccactctgggagaca
tgggcagacctcgtacatcccgacgcccaggacattttggacactttggaggacaatcgt
gagtggtaccagagcacaatcccccagagcccctcccctgcacctgatgaccaagaggac
ggccgtcagggacagactgaaaaattccagttcgaactaaccttagaggaagatggcgag
tcagacactgaaaaggacagtggaagtcaagtggaggaagacactagctgcagtgactct
aagactctgtgcacccaagactcagagtccactgaaattccccttgacgagcaggttgaa
gaggaggctgtagcagaagaggaaagccagccccaaactggcgtcgcagacgattgttgt
cctgacacgtaa
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