Rattus norvegicus (rat): 24640
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Entry
24640 CDS
T01003
Symbol
Pfkfb2
Name
(RefSeq) 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform a
KO
K19029
6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:
2.7.1.105
3.1.3.46
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00051
Fructose and mannose metabolism
rno01100
Metabolic pathways
rno04152
AMPK signaling pathway
rno04919
Thyroid hormone signaling pathway
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00051 Fructose and mannose metabolism
24640 (Pfkfb2)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
24640 (Pfkfb2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
24640 (Pfkfb2)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.105 6-phosphofructo-2-kinase
24640 (Pfkfb2)
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase
24640 (Pfkfb2)
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GFIT
Motif
Pfam:
6PF2K
His_Phos_1
AAA_33
KTI12
His_Phos_2
AAA_18
Motif
Other DBs
NCBI-GeneID:
24640
NCBI-ProteinID:
NP_001029137
RGD:
3309
Ensembl:
ENSRNOG00000004162
UniProt:
Q9JJH5
A6IBZ4
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Position
13:complement(44683499..44727135)
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AA seq
557 aa
AA seq
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MSENSTFSTEDSSSSSYKPHASNLRRAGKKCSWASYMTNSPTLIVMIGLPARGKTYVSKK
LTRYLNWIGVPTKVFNLGVYRREAVKSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYF
TEESGQIAVFDATNTTRERRDMILNFAKQNAFKVFFVESVCDDPDVIAANILEVKVSSPD
YPERNRENVMEDFLKRIECYKVTYQPLDPDNYDKDLSFIKVMNVGQRFLVNRVQDYIQSK
IVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSLRGKQFAQALKKFLEEQEIQDL
KVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYL
YRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPL
HIIFKLTPVAYGCKVETITLNVEAVDTHRDKPTHNFPKSQTPVRMRRNSFTPLSSSNTIR
RPRNYSVGSRPLKPLSPLRALDMQEGADQPKTQVQQGSAQATEHLQKALEFANGHREVEN
VLAKHRRPSMASLTLLS
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atgtctgagaatagtacattttccacagaagacagcagcagcagcagctataaaccccac
gcctcaaacctccgaagggcagggaagaaatgctcatgggcttcctacatgaccaactcc
ccaacactcattgttatgattggcttgccagcccggggtaagacttatgtgtccaagaaa
ttaacacgctacctgaactggattggagtacctaccaaagtgtttaatcttggtgtatat
cgacgggaagcagtcaagtcctataagtcctatgacttctttcgacatgacaatgaagag
gccatgaagatccgcaaacagtgtgccctggtggcactggaagatgtgaaggcctacttt
actgaagagagtgggcagatcgcggtgtttgatgccaccaataccactcgggagaggagg
gacatgattttgaactttgccaagcagaatgccttcaaggtattctttgtggaatctgtg
tgtgatgatcctgatgtcattgctgccaatattctggaggtaaaagtgtcaagccctgac
taccccgaaaggaatagggagaatgtgatggaggacttcctgaagagaattgagtgctac
aaggtcacttaccagccccttgacccagacaactatgataaggacctctcgttcataaag
gtgatgaatgtaggccagaggtttctggtcaacagagttcaggactacatccagagtaag
attgtctactacctgatgaacatccatgtccatcctcgcaccatctatctgtgccggcac
ggagagagcgaattcaatcttttgggaaagattgggggtgactctggcctttcgttgcga
ggaaagcagtttgctcaggctctgaagaagtttctggaggaacaggagatccaggacctc
aaagtgtggacaagccagttgaagaggacaattcagactgctgagtctcttggggtgacc
tatgagcaatggaagatcctaaatgagattgatgctggcgtgtgtgaggagatgacttat
tcggagatcgaacaacggtatccagaggaatttgcacttcgagatcaagagaagtatctg
tatcgatatcctggtggggagtcataccaggacctggtgcagcggctggagcctgtgatc
atggagctggagcggcaaggcaacgtcctcgttatctctcaccaggctgtcatgcgctgc
ctcctggcctacttcttggataaaggcgcagatgagttgccgtacttgaggtgccccctc
cacatcatcttcaaacttactcctgtggcctatggttgcaaagtggaaacaattacactg
aatgtggaagctgtggacacacatcgtgacaagccaactcacaacttccccaagagccaa
acccctgtaaggatgagaaggaacagctttacgcctctgtccagttcgaacacaataagg
cgtccaagaaattacagtgttgggagccgacccctcaagcccctcagccctctccgtgcc
ctggatatgcaagaaggggcggaccagccgaagacccaagtccagcaagggtcagcccag
gctacagaacatctacagaaagccctggagtttgcaaatggacatagggaagtggagaat
gtgctggctaagcatagacgcccctcaatggcatccctcactttgctctcctga
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