Rattus norvegicus (rat): 24653 Help Entry 24653             CDS       T01003                                  Symbol Pla2g4a Name (RefSeq) cytosolic phospholipase A2   KO K16342   cytosolic phospholipase A2 [EC:3.1.1.4] Organism rno  Rattus norvegicus (rat) Pathway rno00564   Glycerophospholipid metabolism rno00565   Ether lipid metabolism rno00590   Arachidonic acid metabolism rno00591   Linoleic acid metabolism rno00592   alpha-Linolenic acid metabolism rno01100   Metabolic pathways rno04010   MAPK signaling pathway rno04014   Ras signaling pathway rno04072   Phospholipase D signaling pathway rno04217   Necroptosis rno04270   Vascular smooth muscle contraction rno04370   VEGF signaling pathway rno04611   Platelet activation rno04664   Fc epsilon RI signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno04724   Glutamatergic synapse rno04726   Serotonergic synapse rno04730   Long-term depression rno04750   Inflammatory mediator regulation of TRP channels rno04912   GnRH signaling pathway rno04913   Ovarian steroidogenesis rno04921   Oxytocin signaling pathway rno05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:rno00001]  09100 Metabolism   09103 Lipid metabolism    00564 Glycerophospholipid metabolism     24653 (Pla2g4a)    00565 Ether lipid metabolism     24653 (Pla2g4a)    00590 Arachidonic acid metabolism     24653 (Pla2g4a)    00591 Linoleic acid metabolism     24653 (Pla2g4a)    00592 alpha-Linolenic acid metabolism     24653 (Pla2g4a)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     24653 (Pla2g4a)    04014 Ras signaling pathway     24653 (Pla2g4a)    04370 VEGF signaling pathway     24653 (Pla2g4a)    04072 Phospholipase D signaling pathway     24653 (Pla2g4a)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     24653 (Pla2g4a)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     24653 (Pla2g4a)    04664 Fc epsilon RI signaling pathway     24653 (Pla2g4a)    04666 Fc gamma R-mediated phagocytosis     24653 (Pla2g4a)   09152 Endocrine system    04912 GnRH signaling pathway     24653 (Pla2g4a)    04913 Ovarian steroidogenesis     24653 (Pla2g4a)    04921 Oxytocin signaling pathway     24653 (Pla2g4a)   09153 Circulatory system    04270 Vascular smooth muscle contraction     24653 (Pla2g4a)   09156 Nervous system    04724 Glutamatergic synapse     24653 (Pla2g4a)    04726 Serotonergic synapse     24653 (Pla2g4a)    04730 Long-term depression     24653 (Pla2g4a)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     24653 (Pla2g4a)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     24653 (Pla2g4a) Enzymes [BR:rno01000]  3. Hydrolases   3.1  Acting on ester bonds    3.1.1  Carboxylic-ester hydrolases     3.1.1.4  phospholipase A2      24653 (Pla2g4a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PLA2_B C2 cPLA2_C2 Motif Other DBs NCBI-GeneID:  24653 NCBI-ProteinID:  NP_598235 RGD:  67366 Ensembl:  ENSRNOG00000002657 UniProt:  Q6IRF5 LinkDB All DBs Position 13:complement(64427921..64572352) Genome browser AA seq 752 aa AA seqDB search MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRT RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEV PFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEG LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSH PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG ETLIQNRMSTTLSSLKEKVSAARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG TFMTPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEE LENITAKHIVSNDSSDSDDEAQGPKGTENEDAEREYQNDNQASWVHRMLMALVSDSALFN TREGRAGKVHNFMLGLNLNTSYPLSPLRDFSPQDSFDDDELDAAVADPDEFERIYEPLDV KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMN KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETK EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRR QNPSRCSVSLSNVEARKFFNKEFLSKPTAESI NT seq 2259 nt NT seq  +upstreamnt  +downstreamnt atgtctttcatagatccttatcagcacataatagtggaacaccagtattcccataagttt acagtagtggttctacgtgccaccaaagtaaccaaggggacctttggcgatatgctggac actcctgatccttatgtggaacttttcatctctacaacccctgacagcaggaagcgaaca agacacttcaataatgatataaaccctgtgtggaatgagacctttgagttcattttggat cctaatcaggaaaatgttttggagatcacattgatggatgccaattacgtcatggatgaa accctaggcacagctacatttcctgtatcttctatgaaggtgggagagaagaaagaagtc ccttttattttcaaccaagtcacagaaatgattctggaaatgtctcttgaagtttgctca tgcccagacctacggttcagcatggcactgtgtgatcaggagaaaacattcaggcagcag aggaaagagaacataaaagagaacatgaagaaacttttgggtccaaaaaagagcgagggg ctttattccacacgtgatgtgcctgtggtggccattttgggttccggcgggggtttccgg gccatggtgggattctccggtgtgatgaaggcgctctatgaatcagggattttggattgt gcgacctacgttgctggtctgtccggctccacatggtacatgtcaaccttgtactcccac cctgattttccagagaaaggtcctgaggagattaatgaagagctaatgaaaaatgttagc cacaaccctctcttacttcttacgccacagaaagttaaaagatatgttgagtctttatgg aagaagaaaagttctggccaacctgtcacctttactgacatctttggaatgttaatagga gaaacactaattcaaaatagaatgagtacgaccttgagtagcttgaaggaaaaggtcagc gccgcccggtgtcctctgcctctcttcacctgtctccatgtcaaaccggacgtgtcagag ctgatgtttgccgattgggtagaatttagtccatacgaaattggcatggcaaaatatggt acctttatgactcctgacctgtttggaagcaaattttttatgggaacagttgtaaaaaaa tatgaagaaaaccccttgcatttcttaatgggtgtctggggcagtgccttttctatactg ttcaacagagttttgggagtttctggctcacagaataaaggttctacaatggaggaggaa ttagaaaatattacagcaaagcacattgtgagtaacgacagctctgacagcgatgacgag gcccaaggacccaaaggcaccgagaatgaagatgcggaaagagagtaccaaaatgacaac caagcaagttgggtccatcggatgctaatggccttggtgagtgactcagctttattcaat acccgagaaggacgtgctgggaaggtgcataacttcatgttgggcttgaatctcaacaca tcgtatccactgtctcccctgagagacttcagcccccaagattccttcgatgatgatgaa ctcgacgcagcggtagcagatccagatgaatttgaacgaatatatgaaccactggatgtc aaaagtaaaaagattcatgttgtagacagtgggctcacgtttaacctgccgtatcccttg attctgcgacctcagagaggtgtggatctcatcatttcctttgacttttctgcaaggcca agtgacaccagccctccattcaaggaacttctgcttgcagagaagtgggctaaaatgaac aagctcccttttccaaagattgatccttacgtgtttgatcgggaaggattgaaggaatgc tatgtgtttaaacctaagaatcctgatgtggagaaggattgcccaaccattatccacttt gttctggccaacatcaacttcagaaagtacaaggccccaggtgttctgagggaaaccaag gaagagaaagaaatagctgactttgacattttcgatgaccccgaatcgccattttcaacc ttcaacttccagtatccaaatcaagcattcaaaaggctacatgatctgatgtacttcaac acactgaacaacattgatgtgataaaggatgccattgttgagagcattgaatacagaaga cagaacccatctcgttgctctgtttccctcagtaatgttgaggcaagaaaattcttcaac aaggagttcctaagtaaacccacagcagagtccatttga

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