Rattus norvegicus (rat): 24655
Help
Entry
24655 CDS
T01003
Symbol
Plcd1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1
KO
K05857
phosphatidylinositol phospholipase C, delta [EC:
3.1.4.11
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00562
Inositol phosphate metabolism
rno01100
Metabolic pathways
rno04020
Calcium signaling pathway
rno04070
Phosphatidylinositol signaling system
rno04919
Thyroid hormone signaling pathway
rno04933
AGE-RAGE signaling pathway in diabetic complications
Module
rno_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
24655 (Plcd1)
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
24655 (Plcd1)
04070 Phosphatidylinositol signaling system
24655 (Plcd1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
24655 (Plcd1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
24655 (Plcd1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
24655 (Plcd1)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
24655 (Plcd1)
Membrane trafficking [BR:
rno04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
24655 (Plcd1)
Endocytosis
Macropinocytosis
Phospholipase C
24655 (Plcd1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
EF-hand_like
EF-hand_10
C2
PH_12
PH
EF-hand_15
EF-hand_6
EF-hand_7
EF-hand_1
WHD_MCM8
SOS1_NGEF_PH
DUF6610
REV1_C
EF-hand_5
TEP1_N
Motif
Other DBs
NCBI-GeneID:
24655
NCBI-ProteinID:
NP_058731
RGD:
3346
Ensembl:
ENSRNOG00000032238
UniProt:
P10688
G3V9D1
A6I3V0
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:complement(127672955..127695939)
Genome browser
AA seq
756 aa
AA seq
DB search
MDSGRDFLTLHGLQDDPDLQALLKGSQLLKVKSSSWRRERFYKLQEDCKTIWQESRKVMR
SPESQLFSIEDIQEVRMGHRTEGLEKFARDIPEDRCFSIVFKDQRNTLDLIAPSPADAQH
WVQGLRKIIHHSGSMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGY
ARKIFRECDHSQTDSLEDEEIETFYKMLTQRAEIDRAFEEAAGSAETLSVERLVTFLQHQ
QREEEAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGNAFSLAHRRVYQDMDQ
PLSHYLVSSSHNTYLLEDQLTGPSSTEAYIRALCKGCRCLELDCWDGPNQEPIIYHGYTF
TSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQRVMARHLRAILGPMLLDQPLDG
VTSSLPSPEQLKGKILLKGKKLGGLLPAGGENGSEATDVSDEDEAAEMEDEAVRSQVQHK
PKEDKLKLVPELSDMIIYCKSVHFGGFSSPGTSGQAFYEMASFSESRALRLLQESGNGFV
RHNVSCLSRIYPAGWRTDSSNYSPVEMWNGGCQIVALNFQTPGPEMDVYLGCFQDNGGCG
YVLKPAFLRDPNTTFNSRALTQGPWWAPKRLRVRIISGQQLPKVNKNKNSIVDPKVIVEI
HGVGRDTASRQTAVITNNGFNPRWDMEFEFEVTVPDLALVRFMVEDYDSSSKNDFIGQST
IPWNSLKQGYRHVHLLSKNGDQHPSATLFVKISIQD
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atggactcgggtagggacttcctgaccctgcacgggctccaggatgacccggaccttcag
gcccttctgaagggcagccagcttctgaaggtgaagtccagctcgtggcgtagggaacgc
ttctacaagctacaggaggactgcaagaccatctggcaggaatctcgaaaggtcatgagg
tccccggagtcgcagctgttctccatcgaggacattcaggaggtacggatgggacaccgc
acagaaggcctggagaagtttgcccgagacatccccgaggatcgatgcttctccattgtc
ttcaaggaccagcgcaacaccctagacctcattgccccatcaccagctgacgctcagcac
tgggtgcagggcctgcgcaagatcatccaccactccggctccatggaccagcggcagaag
ctgcagcactggattcactcctgcttgcgaaaggctgataaaaacaaggacaacaagatg
aacttcaaggagctgaaggacttcctgaaggagctcaacatccaggtggatgacggctac
gccaggaagatcttcagggaatgtgaccactcccagacagactcgctggaggatgaggag
attgagaccttctacaagatgctgacccagcgcgcagagatcgaccgtgcttttgaggag
gccgcaggatccgcggagaccctgtcggtggagaggctagtgacgtttctgcagcaccag
cagcgggaggaggaggcagggccagccttggccctctctctcattgagcgctacgagccc
agtgagactgccaaggcccagcggcagatgaccaaggatggcttcctcatgtacttgctg
tcggctgacggtaacgccttcagcctggcacaccgccgtgtctaccaggacatggaccag
ccactgagtcactacttagtgtcttcttcccacaacacctacctgctggaagaccagctc
acagggcccagcagcacggaggcctacatccgggctctgtgcaaaggctgccggtgcttg
gagctcgactgctgggatggtcccaaccaggaacccatcatctaccacggctacactttt
acctctaagatacttttctgtgacgtgctcagggccatcagggactatgccttcaaggca
tccccctacccagtcatcctgtccctggagaaccactgtagcctggagcaacaacgagtc
atggcccgtcacctgagggctatcctggggcccatgctgttggaccagccactggatggg
gttacctcgagcctgccttcacctgagcaactgaagggcaagatcctgttgaaagggaag
aagctgggagggctgctgcctgctggaggggagaatgggtccgaagccactgacgtgtct
gacgaggatgaggctgctgaaatggaggacgaggctgtgcgcagccaagtgcaacacaag
cccaaggaggataaactaaagctggtgccggagctctccgacatgatcatttactgcaag
agcgtccactttggtggcttctccagtcctggcacctctgggcaggcattctatgagatg
gcttccttttctgagagccgtgccctccggttgctgcaagaatcaggaaatggttttgtc
cgtcataacgtgagctgtctgagcaggatctacccggctgggtggagaacagattcctcc
aactacagtcctgtggagatgtggaacgggggctgccagattgtggctctgaacttccaa
acccctgggccagaaatggatgtttaccttggctgcttccaggacaatggaggctgtggg
tatgtgctgaaacccgcctttctgagagaccccaacaccaccttcaactcacgtgccctg
actcaggggccctggtgggctccgaagaggctccgtgtccggatcatctctggacagcag
ctgccaaaggtcaataagaataagaattctatcgtggaccccaaggtgatcgtggagatc
catggcgtgggccgggacacggctagccgtcagacagcagttattaccaataatggtttc
aacccacggtgggacatggagtttgagtttgaggtaacagtgcctgaccttgccctcgta
cgcttcatggtagaggattatgattcctcttctaagaacgactttattggccagagtact
atcccctggaacagcctcaagcaggggtaccgccatgtccacctcttgtctaagaatgga
gaccagcatccatcagccacactttttgtgaagatctccatccaggactaa
DBGET
integrated database retrieval system
