KEGG   Rattus norvegicus (rat): 24851
Entry
24851             CDS       T01003                                 
Symbol
Tpm1
Name
(RefSeq) tropomyosin alpha-1 chain isoform Tpm1.6cy
  KO
K10373  tropomyosin 1
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04260  Cardiac muscle contraction
rno04261  Adrenergic signaling in cardiomyocytes
rno04814  Motor proteins
rno04820  Cytoskeleton in muscle cells
rno05206  MicroRNAs in cancer
rno05410  Hypertrophic cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09142 Cell motility
   04814 Motor proteins
    24851 (Tpm1)
   04820 Cytoskeleton in muscle cells
    24851 (Tpm1)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    24851 (Tpm1)
   04261 Adrenergic signaling in cardiomyocytes
    24851 (Tpm1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    24851 (Tpm1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    24851 (Tpm1)
   05414 Dilated cardiomyopathy
    24851 (Tpm1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:rno04812]
    24851 (Tpm1)
   04147 Exosome [BR:rno04147]
    24851 (Tpm1)
Cytoskeleton proteins [BR:rno04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Tropomyosins
     24851 (Tpm1)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of microglial cells
   24851 (Tpm1)
SSDB
Motif
Pfam: Tropomyosin CLZ Laminin_II Crescentin ERM_helical Laminin_I PUMA_CC DUF3450 ATG16 TMF_DNA_bd ADIP CENP-F_leu_zip TMP_N DUF745 Lebercilin DUF4200 DUF1664 DUF16 Fib_alpha
Other DBs
NCBI-GeneID: 24851
NCBI-ProteinID: NP_001029241
RGD: 3898
Ensembl: ENSRNOG00000018184
UniProt: P04692 A0A9K3Y6T5 A0A8L2UK34 A6KEY3
Structure
LinkDB
Position
8:complement(76516654..76543661)
AA seq 284 aa
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKY
SEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLELNNM
NT seq 855 nt   +upstreamnt  +downstreamnt
atggacgccatcaagaagaagatgcagatgctgaagctcgacaaagagaacgccttggat
cgagcagagcaggcggaggctgacaagaaggctgcggaagaccggagcaagcagctggaa
gatgagctggtgtcactgcaaaagaaactcaagggcactgaagatgaactggacaaatac
tccgaggctctcaaagatgcccaggagaaactggagctggcggagaaaaaggccacagat
gctgaagctgacgtagcatctctgaacagacgcatccagctggttgaggaggagttggat
cgcgctcaggagcgtctggccacagctctacagaagctggaggaggctgagaaggctgca
gatgagagtgagagaggcatgaaagtcattgaaagccgagcccaaaaagatgaagaaaag
atggagattcaggagatccagctgaaagaggccaagcacattgctgaagatgctgaccga
aagtatgaagaggtggcccgtaagctggtcatcatcgagagcgatctggagcgtgcggag
gagagggctgagctctcggaaggcaaatgtgccgagcttgaagaagagttgaaaacggtg
acgaacaacttgaagtcactggaggctcaggctgagaagtactctcagaaagaagacaag
tatgaagaggagatcaaggttctctctgacaagctgaaggaggctgagacccgggctgag
tttgcagagagatcagtaaccaaattggagaaaagcattgatgacttagaagagaaagtg
gcacatgccaaagaagaaaaccttagtatgcaccagatgctggaccagactttactggag
ctaaacaacatgtga

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