Rattus norvegicus (rat): 25117
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Entry
25117 CDS
T01003
Symbol
Hsd11b2
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase type 2
KO
K00071
corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00140
Steroid hormone biosynthesis
rno01100
Metabolic pathways
rno04960
Aldosterone-regulated sodium reabsorption
Module
rno_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
25117 (Hsd11b2)
09150 Organismal Systems
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
25117 (Hsd11b2)
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Motif
Pfam:
adh_short
adh_short_C2
DUF1776
Motif
Other DBs
NCBI-GeneID:
25117
NCBI-ProteinID:
NP_058777
RGD:
2835
Ensembl:
ENSRNOG00000017084
Vega:
OTTRNOG00000002200
UniProt:
P50233
A6IYQ2
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Position
19:50307569..50312812
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AA seq
400 aa
AA seq
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MERWPWPSGGAWLLVAARALLQLLRSDLRLGRPLLAALALLAALDWLCQRLLPPPAALVV
LAGAGWIALSRLARPPRLPVATRAVLITGCDTGFGKETAKKLDAMGFTVLATVLDLNGPG
ALELRARCSPRLKLLQMDLTKPEDISRVLEITKAHTASTGLWGLVNNAGLNMVVADVELS
PVVTFRECMEVNFFGALELTKGLLPLLRHSRGRIVTVGSPAGDMPYPCLAAYGTSKAAIA
LLMDTFSCELLPWGIKVSIIQPGCFKTEAVTNVNLWEKRKQLLLANLPRELLQAYGEDYI
EHLHGQFLNSLRMALPDLSPVVDAIIDALLAAQPRSRYYTGRGLGLMYFIHHYLPGGLRR
RFLQNFFISHLLPRALRPGQPGPVHDTTQDPNPSPTVSAL
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atggagcgctggccttggccgtcgggcggcgcctggctgctggtggctgcccgcgcgctg
ctgcagctgctgcgctcagacctgcgtctgggccgcccgttgttggcggcgctggccctg
ctggccgctctcgactggctgtgccagcgcctgctgcccccgccggctgcactcgtggtg
ctggctggtgctggctggatcgcgttgtcccgcctagcgcgccctcctcgcctgccggtg
gccactcgcgcggtgctcatcaccggttgtgacactggttttggcaaggagacagctaag
aaactggatgccatgggcttcacggtgctggccactgtgttggatttgaatggccctggt
gctctagaactgcgtgcccgatgttcccctcgcctgaagctgctgcagatggacctgacc
aagccagaggatatcagccgtgttctggaaattaccaaggctcacacggccagcactggc
ctgtggggtctggttaacaatgctggcctcaacatggtagtggccgatgtggaactgtct
ccagtggtaactttccgcgaatgtatggaggtgaacttctttggtgcacttgagctgacc
aagggcctcctgccactcctacgtcactcaaggggacgtattgtgaccgttggcagccca
gcaggagacatgccatacccctgcttggcagcctatggaacctccaaggcagctattgca
ctgctcatggacacattcagctgtgaactgcttccctggggtatcaaggtcagcatcatc
cagcctggctgcttcaagacagaggcagtgactaatgtgaacctctgggagaagcgcaag
caactgctgctggccaacttgcctagagagctgctgcaggcctatggtgaagactacatt
gagcacttgcatgggcaattcctgaattcactcagaatggcattgcctgaccttagcccc
gttgtagatgccatcattgatgcactgctggcagctcagccacgcagccgctactacacg
ggccgtggcctggggctcatgtatttcatccaccactacctgccaggaggcctgcggcgc
cgcttcctacagaacttcttcatcagtcaccttctaccccgagcactgaggcctggccaa
cctggccctgttcatgacacaacccaggacccaaacccttcccccacagtatcagctctg
tga
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