Rattus norvegicus (rat): 25155 Help Entry 25155             CDS       T01003                                  Symbol Syk Name (RefSeq) tyrosine-protein kinase SYK   KO K05855   spleen tyrosine kinase [EC:2.7.10.2] Organism rno  Rattus norvegicus (rat) Pathway rno04064   NF-kappa B signaling pathway rno04072   Phospholipase D signaling pathway rno04151   PI3K-Akt signaling pathway rno04380   Osteoclast differentiation rno04611   Platelet activation rno04613   Neutrophil extracellular trap formation rno04625   C-type lectin receptor signaling pathway rno04650   Natural killer cell mediated cytotoxicity rno04662   B cell receptor signaling pathway rno04664   Fc epsilon RI signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno05152   Tuberculosis rno05167   Kaposi sarcoma-associated herpesvirus infection rno05168   Herpes simplex virus 1 infection rno05169   Epstein-Barr virus infection rno05171   Coronavirus disease - COVID-19 rno05203   Viral carcinogenesis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     25155 (Syk)    04072 Phospholipase D signaling pathway     25155 (Syk)    04151 PI3K-Akt signaling pathway     25155 (Syk)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     25155 (Syk)    04613 Neutrophil extracellular trap formation     25155 (Syk)    04625 C-type lectin receptor signaling pathway     25155 (Syk)    04650 Natural killer cell mediated cytotoxicity     25155 (Syk)    04662 B cell receptor signaling pathway     25155 (Syk)    04664 Fc epsilon RI signaling pathway     25155 (Syk)    04666 Fc gamma R-mediated phagocytosis     25155 (Syk)   09158 Development and regeneration    04380 Osteoclast differentiation     25155 (Syk)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     25155 (Syk)   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     25155 (Syk)    05168 Herpes simplex virus 1 infection     25155 (Syk)    05167 Kaposi sarcoma-associated herpesvirus infection     25155 (Syk)    05169 Epstein-Barr virus infection     25155 (Syk)   09171 Infectious disease: bacterial    05152 Tuberculosis     25155 (Syk)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     25155 (Syk) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      25155 (Syk) Protein kinases [BR:rno01001]  Non-receptor tyrosine kinases   SYK family    25155 (Syk) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 DUF7145 Kdo ABC1 SH2_1 Motif Other DBs NCBI-GeneID:  25155 NCBI-ProteinID:  NP_036890 RGD:  3796 Ensembl:  ENSRNOG00000012160 UniProt:  Q64725 A6J6S3 G3V7N4 LinkDB All DBs Position 17:complement(12756493..12830927) Genome browser AA seq 629 aa AA seqDB search MAGNAVDNANHLTYFFGNITREEAEDYLVQGGMTDGLYLLRQSRNYLGGFALSVAHNRKA HHYTIERELNGTYAISGGRAHASPADLCHYHSQEPEGLVCLLKKPFNRPPGVQPKTGPFE DLKENLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGNISRDESEQT VLIGSKTNGKFLIRARDNNGSFALCLLHEGKVLHYRIDRDKTGKLSIPEGKKFDTLWQLV EHYSYKPDGLLRVLTVPCQKIGVQMGHPGSSNAHPVTWSPGGIISRIKSYSFPKPGHKKP PPPQGSRPESTVSFNPYEPTGGAWGPDRGLQREALPMDTEVYESPYADPEEIRPKEVYLD RKLLTLEDNELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAEANVMQQ LDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHIKDKNIIELVHQVSMGMKYLE ESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINY FKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPPGCPREMYDLMN LCWTYDVENRPGFAAVELRLRNYYYDVVN NT seq 1890 nt NT seq  +upstreamnt  +downstreamnt atggcgggcaatgctgtggacaatgccaaccacctgacctacttttttggcaacatcacc cgggaagaggccgaagactacctggtccagggaggcatgaccgatgggctctacctgcta cgccagagccgcaattacctgggtggttttgctttgtcggtggcacacaacaggaaggca caccactacactatcgagagagaacttaacggcacctacgccatctccgggggcagggcc catgccagcccggcagacctctgccattaccactcccaggaacccgaaggccttgtctgc ctcctcaagaagcccttcaaccggcccccgggggtacagcccaagactggaccctttgag gacctgaaggagaacctcatcagggaatatgtgaaacagacctggaaccttcagggccag gctctggagcaagccatcatcagtcagaagccccaactggagaagttgatcgccacgacg gctcatgagaagatgccctggttccatggcaacatctccagagacgagtcagagcagacg gtcctcatagggtcaaagaccaacggaaaattcctgatcagggccagagacaacaacggc tcctttgcactgtgcctgctgcacgaagggaaggtattacactatcgcatcgacagggac aagaccgggaagctttccatccccgaggggaagaagtttgacaccctctggcagctagtg gaacattactcttacaagccagatgggctattaagagtcctcacggtaccatgtcaaaag attggcgtgcagatgggccacccaggaagttcaaatgcccatcctgtgacttggtcacca ggtggaataatctcaagaatcaaatcctactccttcccaaagcctggccacaaaaagcct cccccaccccaagggagccgtccggagagcaccgtgtccttcaatccctatgagccaacg ggaggggcctggggcccagacagaggccttcagagagaagccctgcccatggacactgag gtatatgagagtccttacgctgaccctgaagagatccggcccaaagaggtctacctggac aggaaactgctgaccctggaggacaatgaactgggctctggcaacttcgggactgtgaaa aagggatactaccaaatgaaaaaagttgtaaaaacagtggctgtgaaaatcctgaagaat gaggccaacgacccggctctgaaggacgagctgctggcggaggccaacgtcatgcagcag ctggacaacccctacattgtgcgcatgatcggaatctgtgaggcggagtcgtggatgctg gtgatggagatggcggagctggggcccctcaacaagtacctgcagcagaacaggcacatc aaggataagaacatcatcgagctggttcaccaggtttccatgggaatgaagtatttggag gagagcaattttgtgcacagagatctggccgcgaggaacgtgcttctggtcacccagcac tacgccaagatcagtgacttcggtctttccaaagccctccgtgctgatgaaaactactac aaggcccagacccacgggaagtggccggtgaagtggtacgcccccgaatgcatcaactac tttaagttctccagtaagagtgatgtctggagcttcggagtcctgatgtgggaagcgttc tcctacgggcagaagccatacagagggatgaaagggagcgaagtgactgccatgctggag aaaggagagcggatggggtgccctccaggatgcccgagagagatgtacgacttgatgaac ctatgctggacttacgatgtggagaacaggccaggattcgcggctgtggaactgcggctt cgcaattactactacgacgtggttaactaa

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