Rattus norvegicus (rat): 25244
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Entry
25244 CDS
T01003
Symbol
Bckdha
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00280
Valine, leucine and isoleucine degradation
rno00640
Propanoate metabolism
rno00785
Lipoic acid metabolism
rno01100
Metabolic pathways
rno01210
2-Oxocarboxylic acid metabolism
Module
rno_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
25244 (Bckdha)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
25244 (Bckdha)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
25244 (Bckdha)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
25244 (Bckdha)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
25244
NCBI-ProteinID:
NP_036914
RGD:
2196
Ensembl:
ENSRNOG00000020607
UniProt:
P11960
Q5EB89
B1WBN3
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All DBs
Position
1:complement(90266731..90295521)
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AA seq
446 aa
AA seq
DB search
MAVAMSAAKIWRPSRGLRQAALLLLGRPGARGLARFHPSRQQQQQFPSLDDKPQFPGASA
EFVDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPQEEVLKLYRSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALERTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNVSDPGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANQIVICYFGEG
AASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRQYLLNQGWWDEEQEKAWRKQSRKKVMEAFEQAERKLKPNPSLLFSDVYQEMPAQ
LRRQQESLARHLQTYGEHYPLDHFDK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagcgatgtccgcggccaagatctggaggccgagccgtggcctgcgccaggct
gccctcttgctgttggggcgacctggggctcggggcttggctagattccaccccagcagg
cagcagcaacagcagttcccatccctggatgacaagccccagttcccaggggcctctgca
gagtttgtagacaagcttgagttcatccagcccaatgtcatctccggcatccccatctac
cgcgtcatggaccgacagggccagatcatcaaccccagtgaagatccccacctgccccag
gaggaggtcctgaagttgtacaggagcatgacgctgctcaacaccatggaccgcattctc
tatgagtcccagcgacagggccggatctccttctacatgaccaactatggcgaggagggg
acacatgtggggagtgccgctgccctggagcgaacggacctggtgtttggccagtaccgg
gaggcaggtgtgctcatgtaccgggactacccgctggagctgttcatggcccagtgctac
ggcaacgtgagtgacccaggcaagggacgccagatgcccgttcactacggctgcaaggag
cgtcacttcgtcaccatttcctctccactggctacgcagatccctcaggcggtaggggca
gcctatgctgccaagcgggccaatgccaatcagatcgtgatctgttactttggcgagggg
gcagccagtgaaggggatgcccacgccggtttcaattttgctgccaccttggagtgtcct
atcatcttcttctgccggaacaatggctatgccatctccacaccaacctctgagcagtac
cgtggggatggcatagcggctcggggccctgggtatggcatcatgtcaatccgtgtggac
ggcaacgatgtgtttgcggtgtacaatgccactaaggaggcccgacggcgggctgtggct
gagaaccagcccttcctcattgaggccatgacctacaggatcgggcaccacagcaccagt
gacgacagctctgcgtaccgttcggtggatgaggtcaattactgggacaagcaggaccac
ccgatctcgagactgaggcagtacctgctgaaccagggttggtgggatgaggaacaggag
aaggcctggcggaagcagtcacgaaagaaggtgatggaggcctttgaacaggctgagcgg
aagctaaagcccaacccaagcctcctcttctccgatgtgtaccaggagatgcctgcccag
ctgcgcaggcagcaggagtccctggctcggcacctgcagacctacggggagcactacccc
ctggaccactttgacaagtga
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