Rattus norvegicus (rat): 252898
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Entry
252898 CDS
T01003
Symbol
Acox2
Name
(RefSeq) peroxisomal acyl-coenzyme A oxidase 2
KO
K10214
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:
1.17.99.3
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00120
Primary bile acid biosynthesis
rno01100
Metabolic pathways
rno03320
PPAR signaling pathway
rno04146
Peroxisome
Module
rno_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
252898 (Acox2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
252898 (Acox2)
09150 Organismal Systems
09152 Endocrine system
03320 PPAR signaling pathway
252898 (Acox2)
Enzymes [BR:
rno01000
]
1. Oxidoreductases
1.17 Acting on CH or CH2 groups
1.17.99 With unknown physiological acceptors
1.17.99.3 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase
252898 (Acox2)
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Gene cluster
GFIT
Motif
Pfam:
ACOX
ACOX_C_alpha1
Acyl-CoA_ox_N
Acyl-CoA_dh_M
Acyl-CoA_dh_1
Motif
Other DBs
NCBI-GeneID:
252898
NCBI-ProteinID:
NP_665713
RGD:
628684
Ensembl:
ENSRNOG00000007378
UniProt:
F1LNW3
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Position
15:19090820..19122392
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AA seq
681 aa
AA seq
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MGSPMHRVSLGDTWSWQVHPDIDSERHSPSFSVERLTNILDGGLPNTVLRRKVESIIQSD
PVFNLKKLYFMTREELYEDAIQKRFHLEKLAWSLGWSEDGPERIYANRVLDGNVNLSLHG
VAMNAIRSLGSDEQIAKWGQLCKNFQIITTYAQTELGHGTYLQGLETEATYDEARQEFVI
HSPTMTSTKWWPGDLGWSVTHAVVLAQLTCLGVRHGMHAFIVPIRSLEDHTPLPGITVGD
IGPKMGLEHIDNGFLQLNHVRVPRENMLSRFAEVLPDGTYQRLGTPQSNYLGMLVTRVQL
LCKGILPSLQKACIIATRYSVIRHQSRLRPSDPEAKILEYQTQQQKLLPQLAVSYAFHFT
ATSLSEFFHSSYSAILKRDFSLLPELHALSTGMKATFADFCAQGAEICRRACGGHGYSKL
SGLPTLVARATASCTYEGENTVLYLQVARFLMKSYLQAQASPGATPQKPLPQSVMYIATQ
RPARCSAQTAADFRCPDVYTTAWAYVSTRLIRDAAHRTQTLMKSGVDQHDAWNQTTVIHL
QAAKAYCYFITVKNFKEAVEKLDKEPEIQRVLQRLCDLYALHGVLTNSGDFLHDGFLSGA
QVDMAREAFLDLLPLIRKDAILLTDAFDFSDHCLNSALGCYDGHVYERLFEWAQKSPANT
QENPAYKKYIRPLMLGWRHKM
NT seq
2046 nt
NT seq
+upstream
nt +downstream
nt
atggggagcccaatgcaccgagtgtccctgggggacacctggagctggcaagtgcacccg
gacatagacagtgaaaggcactcaccgtccttcagtgtggagcgactcaccaacatcctt
gatggaggcctcccaaacaccgtgctgcgaagaaaagtcgaaagcatcatacaaagtgac
ccagtgtttaatttgaagaagctttacttcatgacccgagaggagctatatgaggatgcg
attcaaaagagattccatctcgagaagctagcctggagcctgggctggtcagaagatggt
cctgaacgcatttatgctaacagagtccttgatggaaacgtcaacttaagcttacatggt
gttgccatgaatgctatccgaagcctgggctcagatgaacagattgctaaatggggccaa
ctctgcaaaaacttccaaatcatcacaacatacgcccagacagagctgggacacgggaca
tacctacagggcctggagactgaagccacctatgatgaagccaggcaggagtttgtgata
cacagccctacgatgacttccaccaagtggtggcctggggacttgggatggtcggtcacc
catgctgtggtcctagcccagttgacctgcttaggagtccggcacggcatgcacgccttc
attgtgcccattcggagcctagaggatcacaccccactgccaggaatcacagttggggac
ataggccccaagatgggtttggaacacatagacaatggcttcctgcaactgaaccacgtg
cgggttcccagagaaaacatgctcagtcgctttgcagaggtcttgccagatggtacctac
cagaggcttgggacgccacagagcaattatcttggcatgttggtgacccgggtgcagctg
ctgtgtaaaggaatcctaccctccctccagaaggcttgcatcattgccacgcgctactca
gtaatccgccatcagtctcgacttcggcccagtgacccagaggcaaaaatcctggaatac
cagacgcagcagcagaaactccttcctcagcttgctgtgagctatgccttccacttcacg
gccaccagcctctcagaattcttccacagctcctacagtgctattctgaagagagacttc
agcctcctgcctgagctccatgcattgagcactggtatgaaggccacgtttgcagacttc
tgtgcccagggggccgagatctgtcgcagagcttgtgggggccatggctactcaaagctg
agcggcctgccgacactggttgctcgagcaacagcctcttgcacatatgagggtgagaat
acggtgctctacctgcaagtggccaggtttctgatgaagagctatctgcaggctcaagcg
tccccaggcgccacaccacagaagcctctccctcagtccgtcatgtatattgccacacaa
aggccagccaggtgctcagcccagactgcagctgacttccgctgcccagatgtctatacc
acagcctgggcatatgtgtctaccaggctcataagagatgcagcacaccgtacacagacc
ctcatgaagtccggggttgaccagcatgatgcctggaatcagactactgtcatccacctt
caggctgctaaggcttactgctacttcatcactgtgaagaatttcaaggaagctgtggag
aaactagacaaggaaccagagattcagcgtgtgctccaacgcctctgtgacctctatgcc
ttacacggtgttctgactaactcaggggactttctgcatgatggcttcctgtctggggcc
caggtggacatggccagagaagccttcctagacctgcttcccttgatccggaaggatgcc
atcttgttaaccgatgcttttgacttctcggaccattgtttaaactcggcacttggctgt
tatgatggacacgtctacgaacgcctgtttgagtgggctcagaagtccccagccaatact
caggagaaccctgcctataagaagtatatccgaccactgatgctcggctggagacacaag
atgtga
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