KEGG   Rattus norvegicus (rat): 25315
Entry
25315             CDS       T01003                                 
Symbol
Ephx1
Name
(RefSeq) epoxide hydrolase 1 precursor
  KO
K01253  microsomal epoxide hydrolase [EC:3.3.2.9]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00980  Metabolism of xenobiotics by cytochrome P450
rno04976  Bile secretion
rno05204  Chemical carcinogenesis - DNA adducts
rno05207  Chemical carcinogenesis - receptor activation
rno05208  Chemical carcinogenesis - reactive oxygen species
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    25315 (Ephx1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    25315 (Ephx1)
 09160 Human Diseases
  09161 Cancer: overview
   05204 Chemical carcinogenesis - DNA adducts
    25315 (Ephx1)
   05207 Chemical carcinogenesis - receptor activation
    25315 (Ephx1)
   05208 Chemical carcinogenesis - reactive oxygen species
    25315 (Ephx1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    25315 (Ephx1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.9  microsomal epoxide hydrolase
     25315 (Ephx1)
Peptidases and inhibitors [BR:rno01002]
 Serine peptidases
  Family S33
   25315 (Ephx1)
SSDB
Motif
Pfam: EHN Abhydrolase_1 Abhydrolase_6
Other DBs
NCBI-GeneID: 25315
NCBI-ProteinID: NP_001029262
RGD: 2557
Ensembl: ENSRNOG00000003515
UniProt: P07687 A6JGI7
LinkDB
Position
13:complement(95246079..95275852)
AA seq 455 aa
MWLELVLASLLGFVIYWFVSRDKEETLPLGDGWWGPGSKPSAKEDESIRPFKVETSDEEI
KDLHQRIDRFRASPPLEGSRFHYGFNSNYMKKVVSYWRNEFDWRKQVEILNQYPHFKTKI
EGLDIHFIHVKPPQLPSGRTPKPLLMVHGWPGSFYEFYKIIPLLTDPKSHGLSDEHVFEV
ICPSIPGYGYSEASSKKGLNSVATARIFYKLMTRLGFQKFYIQGGDWGSLICTNMAQMVP
NHVKGLHLNMAFISRSFYTMTPLLGQRFGRFLGYTEKDIELLYPYKEKVFYSIMRESGYL
HIQATKPDTVGCALNDSPVGLAAYILEKFSTWTKSEYRELEDGGLERKFSLDDLLVNIMI
YWTTGTIVSSQRYYKENLGQGIMVHKHEGMKVFVPTGFSAFPSELLHAPEKWVKVKYPKL
ISYSYMERGGHFAAFEEPKLLAQDIRKFVSLAELQ
NT seq 1368 nt   +upstreamnt  +downstreamnt
atgtggctggaacttgtcctggcttcccttctgggctttgtcatctactggtttgtctcc
cgggacaaggaggaaaccttaccactaggagatggatggtgggggccagggtcaaagcca
tcagccaaagaagatgagagcatccggcccttcaaggtggaaacatcagatgaggagatc
aaggacttacaccagaggatagataggttccgggcatccccacctttggagggcagccgc
ttccactatggcttcaactccaactacatgaagaaagtggtgtcctactggaggaacgag
tttgactggaggaagcaggtggagatcctcaaccagtaccctcacttcaagaccaagatc
gaagggcttgacatccacttcatccatgtgaagcctccccagctgccctcagggcgcacc
ccaaagcccttgctgatggtgcatggctggcctggatccttctatgagttttacaagatc
atcccactactgactgaccccaagtcccacggtctgagtgacgagcacgtgtttgaagtc
atctgtccctcgattcctggctatggctactcagaggcatccagcaagaaaggtttaaat
tcggtggccactgcgaggattttctacaagctgatgacacggctgggcttccagaaattc
tacattcaaggcggggactgggggtccctcatctgcaccaacatggcccagatggttccc
aaccacgtgaaaggcctgcacttaaatatggctttcatttcgagaagtttttacaccatg
actcctctcctgggccaacgcttcgggagattccttggctacacagagaaggatatcgag
ctcttgtacccctataaggagaaggttttctacagcatcatgagggagagtggctactta
cacatccaagccaccaagccagacactgtgggctgtgctctcaatgactctcccgtgggc
ctggctgcctacatcttagagaagttctccacctggaccaagtcagagtaccgtgaactg
gaggatggaggcctggagaggaagttctccctggatgatctgctggttaacatcatgatc
tactggacgacaggaaccattgtctcctcccaacgctactacaaggagaatttgggccag
ggcatcatggtccataaacatgaggggatgaaggtctttgtgcccactggcttttcagcc
ttcccttccgagctactgcatgccccagaaaagtgggtgaaggtcaagtaccccaaactc
atctcctattcctacatggaacgtgggggccactttgctgcctttgaagagcccaagctt
ctggcccaggacatccgcaagttcgtgtccctggctgagctgcagtag

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