Rattus norvegicus (rat): 25366
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Entry
25366 CDS
T01003
Symbol
Acvr2b
Name
(RefSeq) activin receptor type-2B precursor
KO
K13596
activin receptor type-2B [EC:
2.7.11.30
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04060
Cytokine-cytokine receptor interaction
rno04350
TGF-beta signaling pathway
rno04550
Signaling pathways regulating pluripotency of stem cells
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
25366 (Acvr2b)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
25366 (Acvr2b)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
25366 (Acvr2b)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
25366 (Acvr2b)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
25366 (Acvr2b)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
25366 (Acvr2b)
Protein kinases [BR:
rno01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
25366 (Acvr2b)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Activin_recp
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
25366
NCBI-ProteinID:
NP_113742
RGD:
2028
Ensembl:
ENSRNOG00000014477
UniProt:
P38445
A0A0G2JSN4
Structure
PDB
PDBj
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All DBs
Position
8:128016589..128056193
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AA seq
512 aa
AA seq
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MTAPWAALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCY
ASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEPG
GPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPP
PSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMK
HENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSY
LHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVG
TRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQ
HPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSL
IRRSVNSSTSDCLVSLVTSVTNVDLLPKESSI
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgacggcgccctgggcggccctcgcccttctctggggatcgctgtgcgccggttccggg
cgaggggaagctgagactcgggagtgcatctactacaacgccaactgggagctggagcgc
accaaccagagcggcctggagcgctgcgagggggaacaggacaagcggctgcactgctat
gcctcgtggcgcaacagctcgggcaccatcgagctggtgaagaagggctgctggctagat
gacttcaattgctacgacaggcaggagtgtgtggccactgaggagaacccccaggtgtat
ttctgctgctgtgaaggcaatttctgcaacgagcgcttcacccatttgccggagcctggg
ggcccagaagtcacgtacgagccacccccgacagcccccaccctgctcacggtgctggcc
tattcgctgctgcccattggaggcctctctctcatcgtcctgctggccttctggatgtac
cgacatcgaaagcctccctacggccacgtggacatccatgaggaccctgggcctcctccc
ccatcgcctctggtgggcctgaagccgctacagttgctggagatcaaggctcgaggtcgc
tttggctgcgtctggaaggctcagctcatgaacgactttgtggctgtgaagatcttccca
cttcaggacaagcagtcgtggcagagtgagcgggagatcttcagcacaccgggcatgaag
cacgaaaacctcctgcagttcattgctgcagagaaacgaggctccaacctggaggtggag
ctgtggctcatcacagccttccacgacaagggctccctcacggattacctcaaggggaac
atcatcacgtggaacgagctgtgtcatgtggcagagacgatgtcacgaggcctctcgtac
ctgcatgaggatgtgccgtggtgtcgtggcgagggccacaagccttctattgcccacagg
gacttcaaaagcaagaatgttctgctgaagagcgacctcaccgcggtgctggctgacttt
ggcctggctgttcggtttgagccggggaagcctccaggggatacccatgggcaggttggc
accagacggtacatggcccccgaggtgctggagggggccatcaacttccagagagacgcc
ttcctgcgtatcgacatgtacgccatgggcctggtgctgtgggagctcgtttctcgttgc
aaggccgcagatgggcctgtcgatgagtacatgctgcctttcgaggaagagattggccaa
cacccttcactggaggagcttcaggaggtggttgtccacaagaagatgaggcccaccatt
aaggatcactggctgaaacatccgggcctggcccagctctgcgtgaccatcgaggagtgc
tgggaccatgatgcagaggctcgtctgtctgcaggctgtgtggaagagcgggtatccctg
atcaggaggtcggtcaacagctctacctcggactgtctcgtctctctggtgacctccgtc
accaatgtggacctgctccctaaagagtccagcatctaa
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