Rattus norvegicus (rat): 25489
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Entry
25489 CDS
T01003
Symbol
Nedd4
Name
(RefSeq) E3 ubiquitin-protein ligase NEDD4
KO
K10591
E3 ubiquitin-protein ligase NEDD4 [EC:
2.3.2.26
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04120
Ubiquitin mediated proteolysis
rno04144
Endocytosis
rno04530
Tight junction
rno05169
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
25489 (Nedd4)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
25489 (Nedd4)
09144 Cellular community - eukaryotes
04530 Tight junction
25489 (Nedd4)
09160 Human Diseases
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
25489 (Nedd4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rno04131
]
25489 (Nedd4)
04121 Ubiquitin system [BR:
rno04121
]
25489 (Nedd4)
03029 Mitochondrial biogenesis [BR:
rno03029
]
25489 (Nedd4)
Enzymes [BR:
rno01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
25489 (Nedd4)
Membrane trafficking [BR:
rno04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
25489 (Nedd4)
Ubiquitin system [BR:
rno04121
]
Ubiquitin ligases (E3)
HECT type E3
25489 (Nedd4)
Mitochondrial biogenesis [BR:
rno03029
]
Mitochondrial quality control factors
Mitochondrial dynamics
Morphogenesis factors
25489 (Nedd4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
DUF6212
Motif
Other DBs
NCBI-GeneID:
25489
NCBI-ProteinID:
NP_037118
RGD:
3157
Ensembl:
ENSRNOG00000058898
UniProt:
Q62940
A6KEM7
A0A0G2K8P3
Structure
PDB
PDBj
LinkDB
All DBs
Position
8:82264751..82349642
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AA seq
889 aa
AA seq
DB search
MSSDMAADDTEAPVLSEDEVWEFCLDKNEEGGGSPGSDVTDTCEPPCGCWELNPSSLEEE
HVLFTADPYLELHNDDTRVVRVKVIAGIGLAKKDILGASDPYVRVTLYDPMSGVLTSVQT
KTIKKSLNPKWNEEILFRVLPQQHRILFEVFDENRLTRDDFLGQVDVPLYPLPTENPRME
RPYTFKDFVLHPRSHKSRVKGYLRLKMTYLPKNGSDDENADQAEELEPGWVVLDQPDAAT
HLQHPPEPSPLPPGWEERQDVLGRTYYVNHESRTTQWKRPSPEDDLTDDENGDIQLQAQR
AFTTRRQISEDVDGPDNHESPENWEIVREDENTMYSGQAVQSPPSGHPDVQVRLAEELDT
RLTMYGNPATSQPVTSSNHSSRGGSSQTCIFEEQPTLPVLLPTSSGLPPGWEEKQDDRGR
SYYVDHNSKTTTWSKPTMQDDPRSKIPAHLRGKTPVDSNDLGPLPPGWEERTHTDGRVFF
INHNIKKTQWEDPRMQNVAITGPAVPYSRDYKRKYEFFRRKLKKQTDIPNKFEMKLRRAN
ILEDSYRRIMGVKRADFLKARLWIEFDGEKGLDYGGVAREWFFLISKEMFNPYYGLFEYS
ATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDGFFIRPFYKMMLQKLITL
HDMESVDSEYYSSLRWILENDPTELDLRFIIDEELFGQTHQHELKTGGSEVVVTNKNKKE
YIYLVIQWRFVNRIQKQMAAFKEGFFELIPQDLIKIFDENELELLMCGLGDVDVNDWREH
TKYKNGYSLNHQVIHWFWKAVLMMDSEKRIRLLQFVTGTSRVPMNGFAELYGSNGPQSFT
VEQWGTPDKLPRAHTCFNRLDLPPYESFDELWDKLQMAIENTQGFDGVD
NT seq
2670 nt
NT seq
+upstream
nt +downstream
nt
atgagctcggacatggcagccgacgacactgaggccccagtgctttcggaggacgaggta
tgggagttctgtctggataagaatgaagagggtggtggatcccccggaagtgatgtcaca
gatacttgtgagccaccatgtggatgctgggagttaaatccgagttccctggaagaggag
cacgtgcttttcactgccgatccatatctcgagcttcacaatgatgacacgcgagttgtg
agagtgaaggttatagctggcataggtctggccaagaaagacatcttgggagccagtgat
ccttatgtaagagtgacattgtatgacccgatgagtggagtccttaccagcgtgcagacg
aaaactatcaaaaagtctttgaatccaaaatggaacgaagaaatactgttcagagtcctt
ccacaacagcaccggattcttttcgaagtgtttgatgaaaatcgtttgacaagagatgat
ttcctgggtcaagtggatgtccctctctatcctttaccgactgaaaacccaagaatggag
agaccatatacatttaaggattttgttcttcatccaagaagccacaaatcaagagttaaa
ggttatctgagattaaaaatgacttacttacctaaaaacggctcagatgatgaaaatgca
gaccaggctgaggagttagagcctggctgggttgttttggaccaaccagatgctgccacc
catttgcagcatccaccagaaccttctcccctacctccagggtgggaagagaggcaggat
gtccttggaaggacctactacgtaaaccatgagtctagaacaacacaatggaaaagacca
agccctgaggatgacctcacagatgatgagaatggtgacattcagctgcaggcgcagcga
gcatttaccaccaggcggcagatatcggaggatgtggatggccctgacaaccacgagtcc
cctgagaattgggagattgtacgagaagatgagaacaccatgtacagtggtcaggctgtt
cagtcgcctccgtcaggtcacccagacgtgcaggtccgcctcgcagaggagttagatacc
agactcaccatgtatggaaacccggccaccagccagccagtcaccagctcaaaccattcc
agcagaggaggcagctcgcaaacctgtatctttgaggaacagcctacacttcctgtgctt
ttgcctacttcatctggattgccaccaggttgggaagaaaaacaagatgacagaggacga
tcgtactatgtagaccacaactctaagacaaccacatggtccaagcccaccatgcaggat
gatccaagatcgaaaattcctgctcatctgagaggaaagacaccagtcgactccaatgac
ctgggacctttacctccaggctgggaagaaagaacgcacacagatggaagggtcttcttc
ataaatcacaatataaagaagacacagtgggaagatcctcggatgcagaatgtggccata
actggaccagcagtgccctactccagagattacaaaagaaagtatgagtttttccgaagg
aagctgaagaagcagactgacattccaaacaaatttgaaatgaaacttcgccgtgcaaac
attctggaggattcttaccggagaattatgggtgtgaagagagctgacttcctcaaggcc
cgactctggattgagtttgatggtgaaaagggccttgactatggaggagttgcccgagaa
tggttcttcctcatctcaaaggagatgtttaatccctattatggcctgtttgaatattcc
gctacggacaattacactctgcagataaatccaaactcgggcttgtgtaatgaagatcac
ctctcatacttcaagttcattggccgtgtggctgggatggcggtttatcatggcaagctg
ttggatgggtttttcatccgccccttttacaagatgatgcttcagaaactgataacactg
cacgacatggagtccgtggatagtgaatattacagttctctgcgatggattcttgaaaat
gacccgacggagctggacctgagatttatcatagatgaagagctttttggacagacacat
caacacgagctgaaaactggtggatcggaggttgtggtcaccaacaagaacaaaaaggag
tatatctaccttgtaatccagtggcgatttgtgaacagaatccagaagcaaatggctgct
tttaaagagggattttttgaactgataccacaggatctgatcaagatattcgatgaaaat
gaactagagcttctcatgtgtggtctgggagatgtggacgtgaacgactggagggaacat
acaaaatacaaaaatggatacagcttaaaccaccaggtcatccactggttctggaaggct
gttttgatgatggattcagaaaaaagaatacgcttacttcagtttgttactggcacatcc
cgtgtgcctatgaatggatttgctgaactctatggctcaaatggaccacagtccttcaca
gtggaacagtggggcacccctgataagctgcccagagcacatacctgcttcaaccgcctg
gacctgccaccctatgaatcctttgacgaactctgggataaacttcagatggcgattgag
aacacgcagggctttgatggggttgattag
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