Rattus norvegicus (rat): 25617
Help
Entry
25617 CDS
T01003
Symbol
Hspa5
Name
(RefSeq) endoplasmic reticulum chaperone BiP precursor
KO
K09490
endoplasmic reticulum chaperone BiP [EC:
3.6.4.10
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno03060
Protein export
rno04141
Protein processing in endoplasmic reticulum
rno04612
Antigen processing and presentation
rno04918
Thyroid hormone synthesis
rno05012
Parkinson disease
rno05014
Amyotrophic lateral sclerosis
rno05020
Prion disease
rno05022
Pathways of neurodegeneration - multiple diseases
rno05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03060 Protein export
25617 (Hspa5)
04141 Protein processing in endoplasmic reticulum
25617 (Hspa5)
09150 Organismal Systems
09151 Immune system
04612 Antigen processing and presentation
25617 (Hspa5)
09152 Endocrine system
04918 Thyroid hormone synthesis
25617 (Hspa5)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
25617 (Hspa5)
05014 Amyotrophic lateral sclerosis
25617 (Hspa5)
05020 Prion disease
25617 (Hspa5)
05022 Pathways of neurodegeneration - multiple diseases
25617 (Hspa5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
25617 (Hspa5)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
rno03110
]
25617 (Hspa5)
04131 Membrane trafficking [BR:
rno04131
]
25617 (Hspa5)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
rno04147
]
25617 (Hspa5)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.6 Acting on acid anhydrides
3.6.4 Acting on acid anhydrides to facilitate cellular and subcellular movement
3.6.4.10 non-chaperonin molecular chaperone ATPase
25617 (Hspa5)
Chaperones and folding catalysts [BR:
rno03110
]
Heat shock proteins
HSP70 / DNAK
25617 (Hspa5)
Membrane trafficking [BR:
rno04131
]
Endoplasmic reticulum (ER) - Golgi transport
Forward pathways
ER-Golgi intermediate compartment (ERGIC) proteins
25617 (Hspa5)
Autophagy
ER-phagy
ER stress-related proteins
25617 (Hspa5)
Exosome [BR:
rno04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
25617 (Hspa5)
Exosomal proteins of other body fluids (saliva and urine)
25617 (Hspa5)
Exosomal proteins of colorectal cancer cells
25617 (Hspa5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSP70
MreB_Mbl
Hydantoinase_A
FtsA
DDR
FGGY_C
ParM_N
Tombus_movement
Motif
Other DBs
NCBI-GeneID:
25617
NCBI-ProteinID:
NP_037215
RGD:
2843
Ensembl:
ENSRNOG00000018294
UniProt:
P06761
A6JUC7
LinkDB
All DBs
Position
3:38453016..38457475
Genome browser
AA seq
654 aa
AA seq
DB search
MKFTVVAAALLLLCAVRAEEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNR
ITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVV
EKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQ
RQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNG
VFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALS
SQHQARIEIESFFEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIV
LVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVC
PLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLG
TFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIER
MVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSPEDKETMEKAVEE
KIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGGPPPTGEEDTSEKDEL
NT seq
1965 nt
NT seq
+upstream
nt +downstream
nt
atgaagttcactgtggtggcggcggcgctgctgctgctgtgtgcggtgcgggcggaggag
gaggacaagaaggaggatgtaggcacggtggttggcatcgacttggggaccacctattcc
tgcgtcggtgtattcaagaacggccgcgtggagatcatagccaacgatcagggcaaccgc
atcacaccgtcgtatgtggccttcactcctgaaggggagcgtctgattggcgatgcggcc
aagaaccaactcacgtccaacccggagaacaccgtcttcgacgccaagcgcctcatcgga
cgcacttggaatgacccttccgtgcagcaggacatcaagttcttgccattcaaggtggtt
gaaaagaaaactaaaccatatattcaagttgatatcggaggtgggcaaaccaagacattt
gccccagaagaaatttctgctatggttctcactaaaatgaaggaaactgccgaggcgtat
ttgggaaagaaggtcacccatgcagttgtgactgtaccagcttacttcaatgatgcacag
cggcaagcaaccaaggatgctggcactattgctggactgaatgtcatgaggatcatcaat
gagccaacagcagctgctattgcatatggcctggataagagagagggagagaagaacatc
ctcgtgtttgacctgggtggtggaaccttcgatgtgtctcttctcaccattgacaatggt
gtctttgaagtggtggccactaatggagacactcatctgggtggggaagactttgatcag
cgggtcatggagcacttcatcaagctgtacaaaaagaagactgggaaagatgtcagaaag
gacaacagagctgtgcagaaactccggcgtgaggtagaaaaggccaagagagccctgtct
tctcagcatcaagcgaggattgaaattgagtccttcttcgaaggagaagacttctcagag
acccttactcgggccaaatttgaagagctgaacatggacctgttccgctctaccatgaaa
cctgtccagaaagtgttggaagactctgatctgaagaaatctgatattgatgagattgtt
ctggttggcggatctactcgaattccaaagattcagcagttggtgaaagagttcttcaat
ggcaaggagccgtcccgtggcatcaacccagatgaggctgtagcatatggtgccgctgtc
caggctggtgtcctctctggtgatcaagatacaggtgacctggttctgcttgatgtgtgt
cctcttacacttggtattgaaactgtgggaggtgtcatgacaaaactgattccgaggaac
actgtggtgcccaccaagaagtctcagatcttctccacagcttctgataatcagcccacc
gtaacaatcaaggtctacgaaggtgaacgacccctgacaaaagacaatcaccttctgggt
acatttgatctgactggaatccctcctgctccccgtggggtaccccagattgaagtcacc
tttgagatagatgtgaatggtattcttcgagtgacagctgaagacaaagggacaggaaac
aaaaacaaaatcaccatcaccaatgaccaaaaccgcctgacccctgaagaaattgaaagg
atggtcaatgacgccgagaagtttgctgaggaagacaaaaagctcaaagagcgcattgac
acgaggaatgaattggaaagctatgcttactctcttaagaaccagatcggagataaagag
aagctgggaggtaagctgtctcctgaagataaagagaccatggagaaagctgtagaggaa
aagatcgaatggctggaaagccaccaggatgcagacattgaagactttaaagctaaaaag
aaggaactagaagaaattgttcagccaattatcagcaaactctatggaagtggaggccct
cccccaactggtgaagaggatacatcagaaaaagatgagttgtag
DBGET
integrated database retrieval system
