Rattus norvegicus (rat): 25748
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Entry
25748 CDS
T01003
Symbol
Alas2
Name
(RefSeq) 5-aminolevulinate synthase, erythroid-specific, mitochondrial
KO
K00643
5-aminolevulinate synthase [EC:
2.3.1.37
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00260
Glycine, serine and threonine metabolism
rno00860
Porphyrin metabolism
rno01100
Metabolic pathways
rno01240
Biosynthesis of cofactors
Module
rno_M00868
Heme biosynthesis, animals and fungi, glycine => heme
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
25748 (Alas2)
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
25748 (Alas2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01007 Amino acid related enzymes [BR:
rno01007
]
25748 (Alas2)
Enzymes [BR:
rno01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.37 5-aminolevulinate synthase
25748 (Alas2)
Amino acid related enzymes [BR:
rno01007
]
Aminotransferase (transaminase)
Class II
25748 (Alas2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Aminotran_1_2
Preseq_ALAS
Aminotran_5
Cys_Met_Meta_PP
DegT_DnrJ_EryC1
Beta_elim_lyase
Motif
Other DBs
NCBI-GeneID:
25748
NCBI-ProteinID:
NP_037329
RGD:
2084
Ensembl:
ENSRNOG00000000167
UniProt:
Q63147
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Position
X:22890650..22914046
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AA seq
587 aa
AA seq
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MVAAAMLLRSCPVLSKGPTGLLGKVAKTYQFLFGIGRCPILATQGPTCSQIHLKATKAGA
DSPSWTKSHCPFMLSELQDRKSKIVQRAAPEVQEDVKTFKTDLLSFMESTTRSQSVPRFQ
DPEQTGGAPPLLIQNNMTGSQAFGYDQFFRDKIMEKKQDHTYRVFKTVNRWANAYPFAQH
FSEASMDSKDVSVWCSNDYLGISRHPRVLQAIEETLKNHGAGAGGTRNISGTSKFHVELE
QELAELHHKDSALLFSSCFVANDSTLFTLAKLLPGCEIYSDAGNHASMIQGIRNSGAVKF
VFRHNDPGHLKKLLEKSDPKTPKIVAFETVHSMDGAICPLEELCDVAHQYGALTFVDEVH
AVGLYGTRGAGIGERDGIMHKLDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFT
TSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVKHMRQLLMDRGFPVIPCPSHIIPIRV
GNAALNSKICDLLLAKHSIYVQAINYPTVPRGEELLRLAPSPHHSPQMMENFVEKLLLAW
TEVGLPLQDVSVAACNFCRRPVHFELMSEWERSYFGNMGPQYVTTYA
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atggtggcagcagctatgttgctacggtcctgtccagtgctctctaagggccccacaggc
ctcctaggcaaagtggctaaaacttaccagttcctatttggtattggacgctgccccatc
ctggccactcaaggaccaacctgttctcaaatccatcttaaggcaaccaaggctggagca
gactctccgtcttggactaagagccattgtcctttcatgctgtcagaactccaagacagg
aagagcaagattgtgcagagggcagctccagaagtccaagaggatgtcaagactttcaag
acagacctgctgagcttcatggagtcaactacccgaagccaatcagtgcctcgtttccag
gatccagagcagactggaggggcacctcccctgctgattcagaataatatgactggaagc
caggcttttggttatgaccaattttttagagacaagatcatggaaaagaagcaggaccac
acataccgtgtgttcaagactgtgaatcgctgggctaatgcctacccctttgcccaacac
ttctccgaggcatctatggactcaaaggatgtttctgtctggtgcagtaatgactatttg
ggcataagcaggcaccctcgtgtcttgcaggccatagaggagaccctgaagaatcatgga
gctggagctgggggcactcgcaatatctcaggtacaagcaagtttcatgtggagcttgaa
caggagctggctgaactacatcataaggactcggctctgctcttctcctcctgttttgtg
gccaatgattctactctctttacactggccaagcttctgccagggtgtgagatctactca
gacgcaggcaatcatgcctccatgatccaaggcattcgtaacagtggtgcagtcaagttt
gtcttcagacacaatgacccaggccacctgaagaaacttcttgagaagtccgatcccaag
acaccaaaaattgtggcttttgagactgttcactccatggatggtgccatctgtcctctg
gaggaattgtgtgatgtggcccaccagtacggggccctgaccttcgtggatgaagtccat
gccgtaggactatatggaacccggggtgcagggatcggggagcgtgatggaattatgcac
aagcttgacatcatctctggaactcttggcaaggcctttggctgtgtcggtggctatatc
gccagcactcgggacttggtggacatggtgcgctcctacgctgcaggcttcatctttacc
acttcactgcctcccatggtgctctctggagctctagagtctgtgcgtctactcaaggga
gaggagggtcaagccctgaggcgtgcacaccagcgcaacgtcaaacatatgcgccagcta
ctaatggacaggggctttcctgttatcccctgtcccagccacatcatccccataagggtg
ggtaatgcggcactcaacagcaagatctgtgatcttctgctcgccaagcacagcatctat
gtgcaggccatcaactacccaactgtgcctcgtggtgaggagctgctgcgcttggccccc
tccccccaccacagccctcagatgatggaaaactttgtggagaagttgctgctggcctgg
actgaggtggggttgcccctccaagatgtgtctgtggctgcatgcaacttctgccgtcgt
cctgtgcactttgagcttatgagcgagtgggagcgatcctactttgggaacatgggaccc
caatatgttactacctatgcctaa
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