KEGG   Rattus norvegicus (rat): 26195
Entry
26195             CDS       T01003                                 
Symbol
COX1
Name
(RefSeq) cytochrome c oxidase subunit I
  KO
K02256  cytochrome c oxidase subunit 1 [EC:7.1.1.9]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno00190  Oxidative phosphorylation
rno01100  Metabolic pathways
rno04260  Cardiac muscle contraction
rno04714  Thermogenesis
rno04932  Non-alcoholic fatty liver disease
rno05010  Alzheimer disease
rno05012  Parkinson disease
rno05014  Amyotrophic lateral sclerosis
rno05016  Huntington disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05208  Chemical carcinogenesis - reactive oxygen species
rno05415  Diabetic cardiomyopathy
Module
rno_M00154  Cytochrome c oxidase
Brite
KEGG Orthology (KO) [BR:rno00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    26195 (COX1)
 09150 Organismal Systems
  09153 Circulatory system
   04260 Cardiac muscle contraction
    26195 (COX1)
  09159 Environmental adaptation
   04714 Thermogenesis
    26195 (COX1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    26195 (COX1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    26195 (COX1)
   05012 Parkinson disease
    26195 (COX1)
   05014 Amyotrophic lateral sclerosis
    26195 (COX1)
   05016 Huntington disease
    26195 (COX1)
   05020 Prion disease
    26195 (COX1)
   05022 Pathways of neurodegeneration - multiple diseases
    26195 (COX1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    26195 (COX1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    26195 (COX1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis [BR:rno03029]
    26195 (COX1)
Enzymes [BR:rno01000]
 7. Translocases
  7.1  Catalysing the translocation of protons
   7.1.1  Linked to oxidoreductase reactions
    7.1.1.9  cytochrome-c oxidase
     26195 (COX1)
Mitochondrial biogenesis [BR:rno03029]
 Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA-encoded proteins
   Cytochrome c oxidase
    26195 (COX1)
SSDB
Motif
Pfam: COX1
Other DBs
NCBI-GeneID: 26195
NCBI-ProteinID: YP_665631
RGD: 621871
UniProt: P05503 Q8HIC9
LinkDB
Position
MT
AA seq 514 aa
MLVNRWLFSTNHKDIGTLYLLFGAWAGMVGTALSILIRAELGQPGALLGDDQIYNVIVTA
HAFVMIFFMVMPMMIGGFGNWLVPLMIGAPDMAFPRMNNMSFWLLPPSFLLLLASSMVEA
GAGTGWTVYPPLAGNLAHAGASVDLTIFSLHLAGVSSILGAINFITTIINMKPPAMTQYQ
TPLFVWSVLITAVLLLLSLPVLAAGITMLLTDRNLNTTFFDPAGGGDPILYQHLFWFFGH
PEVYILILPGFGIISHVVTYYSGKKEPFGYMGMVWAMMSIGFLGFIVWAHHMFTVGLDVD
TRAYFTSATMIIAIPTGVKVFSWLATLHGGNIKWSPAMLWALGFIFLFTVGGLTGIVLSN
SSLDIVLHDTYYVVAHFHYVLSMGAVFAIMAGFVHWFPLFSGYTLNDTWAKAHFAIMFVG
VNMTFFPQHFLGLAGMPRRYSDYPDAYTTWNTVSSMGSFISLTAVLVMIFMIWEAFASKR
EVLSISYSSTNLEWLHGCPPPYHTFEEPSYVKVK
NT seq 1545 nt   +upstreamnt  +downstreamnt
atgctcgtaaaccgttgactcttttcaactaaccacaaagatatcggaaccctctaccta
ttatttggagcctgagcaggaatagtagggacagctttaagtattctaattcgagctgaa
ctaggacagccaggcgcactcctaggagatgaccaaatctataatgtcatcgtcacagcc
catgcattcgtaataattttctttatagtaatacctataataattggaggcttcgggaac
tgacttgtaccactaataattggagcccctgatatagcattcccacgaataaataacata
agcttttgactgcttcctccatcatttctactccttttagcatcctccatagtagaagct
ggagctggaacaggatgaacagtatatccccccttagccggaaacctagcccatgctgga
gcatccgtagatttaactattttttccctccacctagccggggtgtcttctatcttagga
gctatcaactttatcaccactatcattaatataaaaccccctgctataacccaatatcag
acacctctctttgtatgatccgtactaattacagccgtcctactacttctctcactgcca
gtattagcagcaggtatcactatactccttacagaccgaaatctaaatactactttcttc
gaccccgctggaggtggagacccaatcctttatcaacacctattctgattcttcggccac
ccagaagtgtacatcttaattcttccagggtttggaattatttcacatgtagttacctat
tactctggaaaaaaagaacccttcggatatataggtatggtatgagccataatatctatt
ggcttcctaggatttattgtatgagcacatcacatattcacagtaggcctagatgtagac
acccgagcctactttacatctgccactataattatcgcaattcctacaggcgtaaaagta
ttcagctgactcgctacactacatggaggaaatatcaaatgatcccccgccatattatga
gccttagggtttatcttcttattcacagtagggggcctaacagggatcgtactatctaac
tcatcccttgacattgtacttcatgatacatactatgtagtagctcacttccactatgtc
ttatctataggagcagtattcgccatcatagctggcttcgtccactgattcccactattc
tcaggctataccctaaatgacacatgagcaaaagcccactttgccattatatttgtaggt
gtaaacataacattctttcctcaacacttcctaggattagcagggatacctcgtcgttac
tctgattatccagatgcttacaccacatgaaatacagtctcctctataggctcattcatc
tcacttacggccgtccttgtaatgatcttcatgatttgagaagccttcgcatcaaaacga
gaagtactctcaatttcctactcctcaactaacctagaatgactgcatggatgcccccca
ccctaccacacattcgaagaaccttcctatgtaaaagttaaataa

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