Rattus norvegicus (rat): 287379
Help
Entry
287379 CDS
T01003
Symbol
Shmt1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00260
Glycine, serine and threonine metabolism
rno00630
Glyoxylate and dicarboxylate metabolism
rno00670
One carbon pool by folate
rno01100
Metabolic pathways
rno01200
Carbon metabolism
rno01230
Biosynthesis of amino acids
rno01240
Biosynthesis of cofactors
rno01523
Antifolate resistance
rno04981
Folate transport and metabolism
Module
rno_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
287379 (Shmt1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
287379 (Shmt1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
287379 (Shmt1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
287379 (Shmt1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
287379 (Shmt1)
Enzymes [BR:
rno01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
287379 (Shmt1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
287379
NCBI-ProteinID:
NP_001400080
RGD:
1312011
Ensembl:
ENSRNOG00000005275
UniProt:
A0A8I5ZKU9
LinkDB
All DBs
Position
10:complement(45968959..45990341)
Genome browser
AA seq
478 aa
AA seq
DB search
MAERDATVWASHEKMLTQPLKESDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALG
SCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYHLDPQCWGVNVQPYSGSPANFA
VYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPDTGYINYDQL
EENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFE
HCHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGEETYYELESLINSAVFPGLQGGPHN
HAIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRPK
GTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKIAHFIH
RGIELTLQIQSHMTMRATLKEFKEKLTGDEKFQSAVAALREEVENFASNFSLPGLPDF
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
atggcagagagggatgccaccgtgtgggcctctcatgagaagatgttgacacagcccctg
aaggagagcgatgctgaggtttacagcatcattaaaaaggagagcaaccggcagagggtc
ggattggagctgattgcctcggagaactttgccagcagagctgtgttggaggccctagga
tcttgcttaaataacaaatactctgaggggtacccaggccaaaggtattatggtgggact
gagttcatcgatgagctggagacgctgtgtcagaagcgtgcattacaggcctaccatctg
gatcctcagtgctggggcgtcaatgtccagccttattcaggctcccctgcaaactttgct
gtgtatactgccctagtagagccccatgggcgaatcatgggtttggacctgccagatggt
ggccatctgactcatggcttcatgacagacaagaagaaaatctctgccacctctatcttc
tttgaatccatgccttataaggtatacccagacactgggtacatcaactatgaccagcta
gaggagaatgccagcctcttccacccgaagctgatcattgcagggaccagctgctactcc
cggaacctggactatgcgcggctgcgaaagattgcggatgataatggggcatatctcatg
gcagacatggcacacatcagtgggctcgtggcagctggtgtggtgccctcaccctttgaa
cactgtcatgtagtaaccactacaacccacaagaccctgagaggctgccgtgctggtatg
atattctacagaaagggtgtgcgcagtgttgatcccaagactggcgaagagacttactat
gaactggagtccctcatcaactcggccgtgttcccaggcctgcagggcggccctcacaac
catgccattgctggtgttgctgtggccctgaagcaagccatgactacagaattcaaaatc
taccagctccaggtgttggccaactgcagggctctgtctgatgcactcacagagctaggc
tacaaaatagtcacaggtggctctgataatcacttgatcctaatggatctgcgtcctaag
ggtactgatggcggaagggctgagaaggtactggaagcctgttctatcgcctgcaacaag
aatacctgcccaggtgacaagagtgcgttacggcccagtggcctgcgactgggaactcca
gcattgacatcccgaggacttttggaagaagacttccaaaaaatagcacactttatccac
agagggatagagttgactctgcagattcagagccacatgaccatgagggccacactgaaa
gagttcaaggagaagctgacaggggatgagaagttccagagtgctgtggcagctctccgg
gaagaagtggagaattttgcttccaacttctcactacctggacttcctgacttctga
DBGET
integrated database retrieval system
