Rattus norvegicus (rat): 288057
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Entry
288057 CDS
T01003
Symbol
Mylk
Name
(RefSeq) myosin light chain kinase, smooth muscle
KO
K00907
myosin-light-chain kinase [EC:
2.7.11.18
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04020
Calcium signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04270
Vascular smooth muscle contraction
rno04371
Apelin signaling pathway
rno04510
Focal adhesion
rno04611
Platelet activation
rno04810
Regulation of actin cytoskeleton
rno04921
Oxytocin signaling pathway
rno04971
Gastric acid secretion
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
288057 (Mylk)
04020 Calcium signaling pathway
288057 (Mylk)
04022 cGMP-PKG signaling pathway
288057 (Mylk)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
288057 (Mylk)
09142 Cell motility
04810 Regulation of actin cytoskeleton
288057 (Mylk)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
288057 (Mylk)
09152 Endocrine system
04921 Oxytocin signaling pathway
288057 (Mylk)
09153 Circulatory system
04270 Vascular smooth muscle contraction
288057 (Mylk)
09154 Digestive system
04971 Gastric acid secretion
288057 (Mylk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
288057 (Mylk)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.18 myosin-light-chain kinase
288057 (Mylk)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: CAMK group
MLCK family
288057 (Mylk)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
Pkinase
23ISL
V-set
PK_Tyr_Ser-Thr
C2-set_2
fn3
C1-set
Ig_4
BiPBP_C
Kinase-like
Kdo
ATP19
DUF5898
AvrM_N
Motif
Other DBs
NCBI-GeneID:
288057
NCBI-ProteinID:
NP_001099344
RGD:
1310915
Ensembl:
ENSRNOG00000002215
LinkDB
All DBs
Position
11:complement(79288243..79535450)
Genome browser
AA seq
1961 aa
AA seq
DB search
MPGQLPGKTMGDVKLFASSHMSKTSHSVDPSRVSSLPLTEAPAFILPPRNLCVKEGATAK
FEGRVRGHPEPQVTWHRNGQTITNGGRFLLDGGVRGTFSLVIRGVREEDKGKYTCEASNG
SGARQVTVELTVEGDLMKKHGQPVLSKASGFPGETRPSIWGECPPKFATKLGRAVVKEGQ
MGRFSCKITGRPPPQVTWLKGNVPLQPSARVSMSEKNGMQILEIHEVTQDDMGTYTCMVV
NGSGKASMSAELSIPGLDNATRLSRGTKDPSPDIRKEVTNGISKDPETVAESKNCSSPQK
SNFLAQATNSHLKSLQQPKLKPCEDSPRKVLQSSVLQKTSSTIVLQASKVQPEVRAAGIG
ASGPGEERKSLTAPRQATPPTRQCGLGGSVGNKFITGNIPIENQRESRFPKFESQPQSQE
VTEGQTVKFTCEVSGIPKPEVGWFLEGIPVRRQEGIVEIYEDGTSHYLCLPRAGTRDSGR
YSCTASNTLGQVSCSWTLRVDRPSLTQTAPSFSSVLKDSVVIEGQDFVLRCSVRGTPAPQ
VTWLLNGQPIQFARSICEAGEAELHIQDALPEDRGTYTCLAENALGQVSCSATVTVQEKK
GEGERAHRLPPAPSKLFAPIFLQGLSDLKVMDGSQVTMTVQVSGNPPPEVIWLHDGNEIQ
ESEDFHFEQKGGWHSLCIQEVFPEDTGTYTCEAWNSAGEVRTQAILTVQEPHDGTQPWFI
SKPRSVTASLGQSVLISCAIAGDPFPTVHWLRDGKALSRDHGHFELLQNEDVFTLVLKNV
QPWHAGQYEILLKNRVGECSCQVSLMLHKGPSRVPPPRGREPASCEGLCGGGVGAHGDAD
RDGTLRPCWPARGQGWPEEEDGEDVRGLLKRRVETRLHTEEAIRQQEVGQLDFRDLLGKK
VSTKTVSEDDLKDIPAEQMDFRANLQRQVKPKTVSEEERKVHSPQQVDFRSVLAKKGTPK
TPVPEKVPPQKAATPDFRSVLGSKKKSPAENGGNTAEVLNVKAGESPTPAGNAQPVGALK
PIGNAKPAETLKSVGNAKPAETLKPVGNAKPAETLKPVGNVKPAETLKPIANAQPSGSPK
PIANAQPIETQKSVANAKSAETPKLAGKEELKEVRNDVNCKKAHVGATGNEKRPESQGSA
PVFKEKLQDVHVAEGEKLLLQCQVTSDPPATVTWTLNGKTLKTTKFIILAQEGSLFSVSI
EKALPEDRGLYKCVAKNSAGQAECSCQVTVDDAGTSENTKAPEMKSRRPKSSLTPVLGTE
SDATVKKKPASKTPTKAAMPPQIIQFPEDQKVRAGEPVELFGKVTGTQPITCTWMKFRKQ
IQESENIRVENSESGSKLTILAARQEHCGCYTLVVENKLSSRQAQVNLTVVDKPDPPAGT
PCASDIRSSSLTLSWYGSSYDGGSAVQSYNVEIWDTEDKVWTELATCRSTSFNVQDLLPD
REYKFRVRAVNVYGTSEPSQESELTAVGEKPEEPKDEVEVSDDDEKEPEVDYRTVTVNTE
QKVSDVYDIEERLGSGKFGQVFRLVEKRTGKIWAGKFFKAYSAKEKENIRQEISIMNCLH
HPKLVQCVDAFEEKANIVMVLEIVSGGELFERIIDEDFELTERECIKYMRQISEGVEYIH
KQGIVHLDLKPENIMCVNKTGTRIKLIDFGLARRLENAGSLKVLFGTPEFVAPEVINYEP
IGYATDMWSIGVICYILVSGLSPFMGDNDNETLANVTSATWDFDDEAFDEISEDAKDFIS
NLLKKDMKNRLDCTQCLQHPWLMKDTKNMEAKKLSKDRMKKYMARRKWQKTGNAVRAIGR
LSSMAMISGLSGRKSSTGSPTSPINAEKLESEEDVSQAFLEAVAEEKPHVKPYFSKTIRD
LEVVEGSAARFDCKIEGYPDPEVVWFKDDQSIRESRHFQIDYDEDGNCSLIISDVCGDDD
AKYTCKAVNSLGEATCTAELIVETMEEGEGEEGGEEEEEEE
NT seq
5886 nt
NT seq
+upstream
nt +downstream
nt
atgcctggccagttacctgggaagaccatgggggacgtgaaactgtttgcctcgtcgcac
atgtccaaaacctcccacagtgtggatccctcgagggtcagctctctgcctctcaccgag
gcccctgctttcattctgcctcctcggaacctctgcgtcaaagaaggagccaccgccaag
tttgaagggagggtccggggccacccagagccccaggtgacatggcacagaaatgggcaa
accatcaccaatggcggccgcttcctgctggacggtggggtgcgggggactttcagcctc
gtcatccgtggtgtccgtgaggaggacaagggcaagtacacctgtgaagctagcaacggc
agtggcgcccgccaggtgaccgtggagctgactgtggaaggggatcttatgaagaagcat
ggtcagcccgttctttctaaagcctcaggatttccaggggagactcgtcctagcatctgg
ggtgagtgcccgccaaagtttgccaccaagctgggcagagctgtggtcaaagaagggcag
atggggcgattttcctgcaagatcactggccggcctccaccacaggtcacctggctcaag
ggaaatgtcccgttgcagccaagtgcccgagtgtctatgtcagagaagaatggcatgcag
atcctggaaatccacgaggtcactcaggacgacatgggcacgtacacatgcatggtggtg
aatgggtcagggaaagcctccatgtcagcggagctctccatcccaggtttggacaatgcc
accaggttgtcaagaggaaccaaggaccccagtccagacatcaggaaggaggtgaccaat
ggaatctccaaggacccagagactgtggctgaaagtaagaactgttcaagtccccagaag
agcaacttcttagcccaggccaccaacagtcacctcaagtccctgcagcagccaaagctg
aagccgtgtgaagattcccccagaaaggtcctgcagtcctccgtcctgcagaagacctcc
agcaccattgttctgcaggcctcaaaagtccagccagaagtgagagcagcgggcataggg
gcctccggtcctggggaagagaggaagagtctgactgcccctcggcaagccacaccccct
accagacagtgtggcctgggaggctcagttgggaacaaatttatcacggggaacatcccc
atagagaaccaaagggagtcaagatttcccaagtttgagagtcagccccaaagccaagaa
gtcactgaaggtcaaacagtcaagttcacctgtgaggtttcagggataccaaagcctgaa
gtgggttggttcctggaaggcatccccgtgaggagacaagaaggcatcgttgagatttat
gaagacggtacatcccattacctgtgtctgccgagagccgggacgagagacagcgggaga
tacagctgcacagcatccaatacccttggccaagtgtcctgcagttggacgctccgggtg
gaccggccaagcttgacgcagacagccccttccttctctagtgttctgaaggacagtgtt
gtcattgaaggccaggattttgtgctacggtgctctgtacgggggaccccagcaccccag
gtcacttggctgctcaatgggcagcccatccagtttgctcgatccatctgtgaggctggc
gaggccgagctccacatccaggatgccctgcccgaggaccgtggcacctacacctgcctg
gctgagaatgccttggggcaggtgtcctgcagtgccacggtcacggtccaagaaaagaaa
ggcgaaggagagagggcgcaccgtctgcccccagctcccagcaagctcttcgctcccatc
ttcctgcagggtctctctgacctcaaagtcatggatggaagccaggtcactatgacagtc
caggtgtcaggaaacccacctccagaagtcatatggcttcacgacgggaacgagatccag
gagtcagaggacttccacttcgagcagaaaggtggctggcacagcctatgtatccaggaa
gtgttcccggaggacacgggcacatacacctgtgaggcctggaacagcgctggggaggtc
cgcacccaggccatactcaccgtgcaagagccccatgatggcacccagccctggttcatc
agcaagcctcgttcggtgacagcctccctgggccagagtgtcctcatctcctgcgccata
gctggagacccctttcccactgtgcactggctccgagatggcaaagccctctccagggac
catggccactttgagctgctccagaatgaggacgtgttcaccctggttctaaagaacgtg
cagccctggcatgccggccagtatgagatcctgctcaagaaccgggttggcgagtgcagt
tgccaagtgtcactgatgctgcacaaaggtccttccagagtcccaccaccacgggggcgg
gagcctgccagctgtgagggcctctgtggtggaggagttggtgctcatggtgatgctgac
cgtgatgggaccctgaggccctgctggccagcaagagggcagggttggcctgaggaggaa
gacggagaagacgtgagggggctgttgaagagacgggtggagaccaggctgcacacagaa
gaggccatccgccagcaggaggtggggcagctggattttcgagacctcctgggaaagaag
gtgagcacaaagaccgtatcagaagacgacctgaaggacatcccagccgagcagatggat
ttccgcgccaaccttcagcggcaagtgaagccaaagactgtgtctgaggaagagaggaag
gtgcatagcccccagcaggttgacttccggtctgtcctagccaagaaggggacccctaag
acccctgtccctgagaaggtgccacctcaaaaagctgccaccccagactttcgctcagtg
ctaggtagcaagaagaagtcgcctgcggagaatgggggcaacactgctgaggtcttgaat
gtcaaggctggggaaagccccacgcctgcaggcaatgcacagccagtcggggccctgaaa
cccataggcaacgccaagcctgctgagaccctgaagtccgtgggcaatgccaaaccagca
gagaccctgaagcccgtggggaatgccaagccagcagagaccctgaaacccgtaggtaat
gtcaagcctgccgagaccctgaagcccatagccaacgcacagccttcagggtccccaaaa
cccatagccaacgcacagcctattgagacccagaagtctgtggccaatgccaagtctgcc
gagaccccgaaactagcggggaaagaagaactcaaggaggttaggaatgatgtgaactgt
aagaaagcgcatgtcggagccaccggcaatgaaaaaagacctgagagccaaggctcggcc
ccagttttcaaggaaaagctacaagatgtccatgtggctgagggcgagaagctgctactc
cagtgccaggtgacctctgatcctccggccactgtcacctggacactgaatggaaagaca
ctcaagaccacaaaattcatcatcctcgcccaagaaggctcactcttctccgtctccatc
gagaaggcactgcctgaggacaggggtctatacaagtgtgtagccaagaacagcgctggc
caggcggaatgttcctgccaagtcactgtggacgatgctgggaccagcgagaacaccaag
gccccggagatgaaatcccggagacccaagagctctcttacgcctgtgctaggaacggaa
agtgatgctactgtgaaaaagaaacctgcctccaagacacctacaaaagcagctatgcct
cctcagatcatccagttccctgaggaccagaaggtgcgtgctggagagccagtggagctg
tttgggaaagtgaccggtacccagcccatcacctgcacgtggatgaagttccgaaagcag
atccaggagagcgagaacatcagggtggagaacagtgagagcggcagcaagctcaccatc
ctggctgcacggcaggagcactgtggctgctacacactggtggtggagaacaagctgagc
agcagacaggcccaagtcaacctcacggttgtggataagccagaccccccggctggcaca
ccttgtgcttctgacatacggagttcctcgctcaccctgtcctggtatggctcctcgtat
gatgggggcagtgccgtacagtcctacaatgttgagatctgggacacggaggacaaggtg
tggacagagctagccacgtgccgcagcacctctttcaatgtccaagacctgctgcctgac
cgcgagtataaattccgagtacgtgcagtcaacgtctacggaaccagcgagccgagccag
gagtctgagctcaccgcagtgggagagaagcctgaagagccaaaggatgaagtggaagtg
tccgatgatgacgaaaaggagcctgaggttgattaccggacggtgacggtgaacactgaa
cagaaagtatctgatgtatatgacattgaagagcgactaggatctgggaaatttggacaa
gtcttccgacttgttgaaaagagaactggaaaaatctgggcagggaaatttttcaaggcc
tattccgccaaggagaaagaaaacatccgtcaggagatcagcatcatgaactgtctccac
caccccaagctggtccagtgcgtggatgccttcgaagaaaaggccaacatcgtcatggtt
ctggagattgtgtcagggggtgagctatttgagcgcatcattgatgaggacttcgagcta
acagagcgggagtgcatcaagtacatgaggcagatttcggaaggggtggagtacatccac
aagcagggcatcgtgcatctggacctcaagcctgagaacattatgtgtgtcaacaagaca
ggcaccaggatcaagctcattgacttcggcctggcacgaagactcgagaacgctgggtct
ctgaaggtcctctttgggaccccagagtttgtggctcctgaggtgatcaactatgagccc
atcggctacgccacagacatgtggagcatcggggtcatctgctatattctggtcagcgga
ctttcccccttcatgggtgacaatgataacgaaactttagccaatgtcacttcagctacc
tgggacttcgacgacgaggcgttcgatgagatctcggaagatgcgaaggacttcatcagt
aacttgctaaagaaagatatgaaaaaccgtctggactgcacccagtgccttcagcaccca
tggctgatgaaagacaccaagaacatggaggccaagaagctgtccaaggaccggatgaag
aaatacatggcaagaaggaagtggcagaaaacaggcaatgctgtgagagccattgggaga
ctgtcctctatggcaatgatctcagggctcagtggcaggaaatcttcaacagggtcacca
accagcccgatcaatgcagagaagctagagtctgaagaagatgtctcccaggccttcctc
gaggctgttgctgaggaaaagccccatgtaaagccctacttctctaagaccattcgtgac
ctggaggttgtggagggaagcgctgctagatttgactgcaagatcgaaggatacccagac
cctgaggttgtctggttcaaggatgaccagtcaatcagggagtcccgccacttccagata
gactacgatgaagacgggaactgctcgctaattatcagtgatgtctgtggggatgatgac
gccaagtacacctgcaaggctgtcaacagcctcggagaagccacctgcaccgcggagctc
atcgtggagaccatggaggaaggggaaggggaggaggggggggaggaggaggaggaggag
gagtga
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integrated database retrieval system
