Rattus norvegicus (rat): 289094 Help Entry 289094            CDS       T01003                                  Symbol Hmcn1 Name (RefSeq) hemicentin-1 precursor   KO K17341   hemicentin Organism rno  Rattus norvegicus (rat) Brite KEGG Orthology (KO) [BR:rno00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04990 Domain-containing proteins not elsewhere classified [BR:rno04990]     289094 (Hmcn1) Domain-containing proteins not elsewhere classified [BR:rno04990]  EGF-like domain-containing proteins   hEGF / cEGF domain-containing proteins    289094 (Hmcn1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  I-set Ig_3 Ig_2 ig V-set C2-set_2 EGF_CA TSP_1 VWA_4 G2F cEGF C2-set_3 TSP1_spondin C1-set Ig_C17orf99 GBD_Hemicentin FXa_inhibition TSP1_CFP_C EGF_3 TSP1_ADAMTS EGF hEGF DRL_cat VWA7_4 Motif Other DBs NCBI-GeneID:  289094 NCBI-ProteinID:  NP_001258221 RGD:  1564772 Ensembl:  ENSRNOG00000028627 Vega:  OTTRNOG00000001030 LinkDB All DBs Position 13:complement(65165532..65634681) Genome browser AA seq 5635 aa AA seqDB search MIAQELVHTVFLVALFHSSLAGVGTPQSESRAEEIPEGASTLAFVFDVTGSMYDDLVQVI EGASKILETSLKRPKRPLYNFALVPFHDPEIGPVTITTDPKKFQYELRELYVQGGGDCPE MSVGAIKIALEISLPGSFIYVFTDARSKDYRLTHEVLQLIQQKQSQVVFVLTGDCDDRNH IGYKVYEEIASTSSGQVFHLDKKQVNEVLKWVEEAVQASKVHLLSTDHLEHAVNTWKIPF DPSLKEVTVSLSGPSPVIEIRNPFGKLIKKGFGLNELLNIHNSAKVVNVKEPEAGMWTVK TSSSGRHSVRLTGLSTIDFRAGFSRKPTLDFKKTMSRPVQGIPTYVLLNTSGISSPARVD RLELLSISGGSLKTIPVKHYPDRKPYGIWNISDFIPPDEAFFLKVTGYDKEDYLFQRVSS VSFSSIVPDAPKVTMPTRTSGYYLQPGRILCSVESLLPFTLSFVRNGIALGVEQYLKESA SVPWDFPKVTLSDEGFYECIAMNSAGTGRAQTFFDVSEPPPIIQVPNNVTVTPGERAVLA CLVISAVDYNLTWQRSGRDVRLADSARIRTLANLSLELRSVKIGDAGEYRCVVSSEGGSA AASVFLTVQEKPKVTVMPRNQSFTGGSEVSIMCSATGYPKPKIVWTINEMFILGSHRYRM TAEGTLFIKNAVPKDAGTYSCLASNEAGTDEQTSTLRYIEAPKLVVVQSELLVALGDTTV MECKTSGIPPPQVKWFKGDLELRPSTFLSIDPLMGLLKIQETQDLDAGDYTCVAANDAGR ATGSLTLDVGSPPVFIQEPSDVSMEIGSNVTLPCYVQGYPEPKIKWRRLDNMPVFSKPFS VSSISQLRTGALFISNLWASDKGTYICEAENQFGKIQSQTTVTVTGLVAPLIGISPSKAS VIEGQPLTLPCTLLAGNPIPERRWMKNSAMLVQNPYITVRSDGSLHIERVRLQDGGEYTC VASNVAGTNNKTTSVAVHVLPTIQHGQQILSTIEGVPVTLPCRASGIPKPSITWSKKGEL ISTGNAKFSAGADGSLYVVSPGSEESGEYICTATNAAGYAKRKVQLTVYVRPRVFGDQRG LSQDKPVEISVLAGEEATLPCEAKSLPPPIITWAKDSQLISPFSPRHTFLPSGSMKITET RISDSGMYLCVATNIAGNVTQSVKLSVHVPPKIQHGNRHLKVQVGQRVDIPCNAHGSPPP VITWFKSGRPMPFNGVQHPGSPDGMLTIEQTTLSDAGTYTCTATNIAGSDEAEVTLHVQE PPTVEDLQPPFNTPFQERLANQRMAFPCPAKGTPKPTIKWLHNGKEVTGQEPGVSILEDG ALLVIASVTPLNNGEYICVAVNEAGTTERKYNLRVHVPPVIKDKEHVSNVSVLVNQLASL YCEVEGTPSPVIMWYKDDIQVTESSTVQIVNNGKILKLFKASAEDTGRYSCKAINIAGTS QKDFSVNVLVPPSIQGAGSPNEVSVVLNHNITLQCPVRGTPFPAIHWFKDGKPLFLGDPN IELSDRGQNLHLRNARRSDKGRYQCSVSNAAGKQAKDIKLTLYVPPSIKGGNVTTEISAL LNSVVKLECETRGLPVPAITWYKDGQVVTSSSQALYIDKGQFLHIPRAQVSDSATYTCHA SNVAGTAEKSFHVDIYVPPIIEGDLTTPSSKQVVVGQSLVLECKAVGNPPPVLTWLKDGV PVKASDNIHIEAGGKKLEILSALEVDRGQYICVATSVAGEREIKYEVDVLVPPAVEGGDE TSYFIVLANNLLELDCQVSGSPPPTIMWLKGGQLIDERDGFKILLSGRKLVIAQAQVSDT GLYQCVATNVAGDRRKEFEVTVHVPPTIKSSDLPEKTVVRYKPVSLQCIANGIPNPSITW LKDDQPVNTAPGNLRIQSSGRVLQIAKALLEDAGRYTCVATNAAGEAHQHTQLHVHEPPS LDDGGKMLNESVVVNNPIQLECKATGSPVPVLTWYKDSHPLAGSTSATFLKRGQILEIGS AQISDAGIYKCVAINSAGATELFYSLQVHVPPSISGSSSMVEVVVNNLARLECEARGIPA PSLTWLKDGSPVSSFSNGIQVLSGGRILALTSAQMSDTGRYTCVAVNAAGEKQRDFDLRV YAPPNIMGEEQNVSVLISQTVELFCQSDAVPPPTLMWFKDGRPLLKRPGLSISENGSVLM IEDAQAGDTGRYTCEATNVAGKTEKNYNVNIWVPPSIYGSDELVQLTAIEGNLITLLCES SGIPPPNLTWKKKGSLVLADAAGRVHILSGGRRLQISIAEKADAGLYTCVASNVAGIAKK EYNLQVYIRPSIANSGSHRPEITVIRGRSISLECEVQGIPQPTVTWMKDGRPLSKGKGVE ILDEGRVLQLKNVHVSDTGRYVCVAVNVAGMTDKRYDLSVHVPPSIIGNHGVPENISVVE KSSVSLTCEASGIPLPSITWLKDGWPVSLGSSVKILSGGRMLRLMQTRPEDAGQYTCIVR NAAGEDRKMFGLSVLVPPHIVGDNTLEDIKIKEKQSVTLTCEVRGNPVPQITWHKDGQLL QEDEVHHMMSGGRFLQITNAQVSHTGRYTCLASNIAGDKSKSFSLNVFVSPTIAGVDSDG SPEDVIVILNSPTSLVCEAYSYPPATITWFKDGAPLESSRNLRILPGGRTLQILNAQEDN AGRYSCVATNEAGEMIKHYEVKVYIPPIIKKGDLLGTGLSPKEVKIRVNSSLTLECEAYA IPSASLRWYKDGQPLKSDHHVNIAENGHTLQIKEAQISDTGRYTCVASNLAGEDELDFDV NIQVPPSFQKLWEIGNMLDTGRSGEAKDVIINNPISLHCETNAAPPPTLTWYKDGRPLTS SDRVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDIHVLLPPVIKGANSDLPE EVTVLVNKSAQMECSSSGSPAPRNFWQKDGQPLLEDEHHKFLSDGRVLQILNAQITDTGR YVCVAENTAGSAKKYFNLNVHVPPSVIGPNHEHLSVVVNHFISLTCEVSGFPPPDLNWLK NEQPIKPNTNVLIVPGGRTLQIIRAKVSDGGEYTCVAINQAGESKKKVSLTVHVPPSIKD HGSESLSIVNVREGTSVSLECESNAVPPPVITWSKNGRMIPDSSNVAILTGGQMLHIRRA EVADTGQYVCRAINVAGRDDKNFHLNVYVPPTIEGPETEVIVETMSNPVTLTCDATGIPP PTITWLKNHKPIENSDPLEAHILSGGSKLQIARLQRSNRGNYTCVASNMEGKAQKNYILS IQVPPSVAGAEVPSEVSVLLGENVELVCDADGIPIPRLQWLRDGKPIVSGETERVRVTTD GSTLNIYRALTSDMGKYTCVATNPAGEEDRIFNLNVYVPPKIRGNKEEAEKLMALVDTSL NIECKATGTPPPQISWLKNGLPLPISSHIRLLSAGQAIRIVRAQVSDVAVYTCVASNRAG IDSKRYSLQVFVPPNMDNAMGTEEITLVKGSSTSMTCFTDGAPTPSMSWLRDGQPLALDA HLTIGTQGMVLQLIKADTEDTGKYTCVASNEAGEVSKHFVLKVLEPPHINGSEGPGEVSV IVNNPLELSCIASGIPAPKISWMKDGRPFLQTEQVQTLEGGAILRVSSAQVEDTGRYTCL ASSPAGDDDKEYLVRVHVPPNIAGVDEAQDFTVLRNRQVTLECKSDAVPPPVIMWLKNGE QLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILTVNVPPSISGGPQ SLVTLLNKSIALECLAEGVPSPRITWRKDGVVLAESHARYSILENGFLHIQSAHITDTGR YLCMATNVAGTDRRRIDLQVHVPPSIAAGPTNVTVTVNVQTTLACEATGIPKPSINWRKD GHLLNVDQNQNSYRLLSSGSLIIISPSVDDTASYECTVTSDAGEDKRTVDLTVQVPPTIA DEPMDFLVTRQAPAVMTCSASGVPLPSIHWTKNGIRLLPRGDGYRILSSGAIEISAAQLN HAGRYTCIARNAAGSVHRHVTLRVQEPPFIQPQPSELDVILNNPILLPCEATGIPTPFIT WQKEGINVITSGKSLAVLPSGSLQISRAVQGDAGTYMCVAQNPAGTALGKIKLNVQVPPA ISSHQKEYVVTMDKPVSLLCETEGSPPPDITWHKDGHALTESIRQRILNSGALQIAFAQP DDAGQYTCMAANMAGSSSMSTTLTVHVPPRIQSTEVHYTVNENSQVVLPCVADGIPTPAI HWERDSVLLANLLGKYTAQPYGELVLENVVLEDAGTYTCVANNAAGEDTHTVTLTVHALP TFTELPGDLSLNKGEQLRLSCKAVGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIEKVSK EDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNAILNCEVKGDPAPT IQWSRKGADVEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAANEAGVVERSMSLTLQSSP MITLEPVETIVDAGGRVTLDCQAAGEPQPTITWSRQGRPIPWDNRLTMLPNSSLYIAAAR KEDTSEYECVARNLMGSVLVRVPVIVQVHGGFSLWSAWRSCSVTCGKGIQKRSRLCNNPP PANGGRPCQGSESEARQCQNKLCPVDGHWSEWSFWEECSRSCGHGNQTRTRTCSNPPAQH GGRPCEGYAVETIMCNIRPCPVHGVWNAWQPWGSCSKSCGKGSQTRTRLCNSPPPSFGGA YCNGAETQMQVCNERHCPVDGKWAAWTSWSTCTVSCGGGTRKRTRDCSDPVPQYGGNKCE GTGVQSDFCNSDPCPTHGNWSPWSGWGMCSRTCNGGQMRRYRTCDNPRPSNGGRACGGPD TQIQRCNTDMCPVDGSWGTWHSWSHCSVSCGGGERTRKRLCDNPVPSKSGRSCPGDATQV SRCNMQACPGGPQRARGSVIGNINDIEFGIAFLNATITDSPNSDTRIIQATITNVPRSLG PAMRKIISILNPIYWTTAKEIGEAVNGFTLTNAVFKRETQVEFATGEVLRMTHVARGLDS DGALLLDVIVSGHVLQLHSPAEVSVKDYTEDYIQTGPGQLYAYSTRLFTIDGISVPYTWN HTIFYDQAWGKMPFLVETLHASSVESDYNQLEETLGFKIHASISKGDRSNQCPSGFILDS AGPFCADEDECTAGNPCSHTCHNAIGAYYCSCPKGLTIAADGRTCQDIDECALGGHTCHA GQDCDNTIGSYRCVVHCGTGFRRTSDGLSCQDINECQESSPCHQRCFNVIGSFHCGCEAG YQLKGRKCIDVNECRQSVCRPDQHCKNTRGGYKCIDLCPSGMTKAENGTCIDIDECKDGT HQCRYNQICENTRGSYRCACPRGYRSQGVGRPCVDINECDQVPKPCAHQCSNSPGSFKCI CLPGQHLLGDGKSCAGLERLSSYGTQYSSYDLERFSPVRSGYQPRQHTRQQSQLYSSYSE YRNSRASFSRSRRTIRKTCPEGSEANHETCVDIDECQNRDTCQHECKNTIGSYQCVCPPG YRLMLNGKTCQDVDECLEQNVRCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVLGFCLKNC PPNDLECTLSPYALEYKLVSLPFGIAANQDLIRLVAYTQDGVMHPRTTFLMVDEEPAVPF ALRDENLKGVVYTTRPLREAETYRMKVRALSYSANGTIEYQTTFIVYIAVSAYPY NT seq 16908 nt NT seq  +upstreamnt  +downstreamnt atgattgcccaggaactggtccacacagttttcctggtggctctttttcattcttcccta gctggagttgggaccccgcagtcggagagcagggctgaggagattccggagggggcgtcc acgttggcttttgtgtttgatgtgactggctccatgtatgatgatttagttcaggttatt gaaggggcttccaaaattttggagacgtctttgaaaagacctaagagacctctttacaac tttgctttggtgcccttccatgatccagaaatcggtccagtgacaattaccacagatccg aaaaaatttcagtatgaactgagagaactgtatgttcagggaggtggcgattgtccagaa atgagtgtcggggctataaagattgccctggaaatttctcttcctggttccttcatctat gttttcactgatgcacgatccaaggattatcgtctcacccatgaggtgctgcagcttatc cagcagaaacaatcccaagtggtatttgtgctcactggagactgtgatgacaggaaccat attggatacaaagtctatgaagaaattgcttctacaagttctggtcaagtgttccatctg gacaaaaagcaagtaaatgaggtgttgaagtgggtggaagaagcggtgcaggcctccaag gttcacctcttatccaccgaccatttggaacacgctgtaaatacttggaaaattcctttt gatcccagcctcaaagaagttactgtgtccctgagtggcccttctcccgtgattgaaatt cgcaatcctttcgggaagctgataaaaaaggggtttggcttgaatgagctgttaaatatc cataactctgccaaggtggtgaacgtcaaagagcccgaagctggaatgtggacagtgaag acctccagcagtggaaggcattctgttcgcctcaccggtctcagcactatcgatttccga gctggcttttctcgaaagcccacgctggacttcaaaaaaacaatgagcagacccgtgcaa gggatacctacgtatgtgctactgaacacctctggaatctctagtccagctagagtagat cgcctcgaacttctgagtatctcagggggatctcttaagaccattcccgtcaaacattac ccagatcggaaaccttacggcatctggaatatctctgacttcattccaccagatgaagct ttctttctcaaggtgacaggctatgacaaagaggattatctcttccagagagtgtcaagc gtttccttttccagcattgtcccagatgctcccaaagttacaatgcccacgaggacctca ggatactacctacagccaggccgaatcctctgctcggttgagagtcttttgccctttact ttgagcttcgtgagaaatggaattgccctgggagtagagcaatatttaaaagaatctgcc agtgtgccttgggatttcccaaaggtgacgttgtctgacgagggcttctacgagtgtatt gctatgaacagcgcaggaactggacgggcgcagacattttttgatgtatcagagccccct ccgatcatccaagtgcctaataatgtaacagtcactcctggagaaagagcagttttggcg tgtctcgtcatcagtgccgtggattataacctaacctggcagaggagtggcagggatgtc cggctagcagactcagcaagaattaggaccctggccaacctctccctggagctgcggagt gtgaaaattggtgatgctggggagtaccgttgtgtggtttccagtgaagggggatcggca gcagcttcggttttcctgacagtacaagaaaaacccaaagtcaccgtgatgcccaggaat cagtctttcacaggagggtctgaggtctccatcatgtgctctgcaacaggctatcccaaa ccaaagattgtctggaccattaatgagatgtttatcctgggttcacacagatacaggatg accgcagaaggcactttattcatcaagaacgcagttcccaaagatgcagggacctacagt tgcctggcaagcaatgaggccgggacagacgagcaaacttccactctcagatacatagaa gccccaaagttggtggtagttcagagcgagctcttggtggcccttggggatacaacagtt atggaatgtaaaacctctgggattcccccacctcaagtaaagtggttcaaaggagatctc gagctgaggccctcgacgttcctcagtattgaccctctcatgggtcttttgaagattcaa gaaacacaagatctggatgctggcgattatacctgtgtagccgccaatgacgctggaaga gccacaggcagtctaactctggatgtaggctcacctccggttttcatacaagaaccttct gatgtgtccatggaaattggctccaatgtgacattaccttgttatgttcagggttatcca gaaccaaagatcaaatggcggagattggacaacatgccagttttctcaaaacccttttca gttagttccatcagccagctgagaacaggagctctctttatttcaaatttatgggcaagt gataaaggaacgtacatctgtgaagcagaaaaccagtttggaaaaatacagtcgcagaca acagtaacagtgacaggacttgttgccccacttattggaatcagcccttccaaagccagt gtgattgaaggacagccactaaccttgccttgtactctgttggctggaaatcccattcca gaacggcggtggatgaagaactcagccatgttggtacaaaatccctacataactgtgcgc agcgatgggagcctccatattgaaagagttcgacttcaggatggaggcgaatatacttgt gtggccagtaatgttgctggaaccaataacaaaacaacctctgtagccgtgcatgttctg cctaccattcagcacggacagcagatactcagcaccattgaaggcgttccagtaactttg ccatgcagagcgagtgggatccccaagccgtctatcacttggtcgaagaaaggagagctg atttcaacgggcaatgccaagttttctgcaggggctgatgggagtctgtatgtggtgtca ccaggaagcgaggagagtggagagtacatctgcacagccaccaatgcagccggctatgcc aagaggaaagtgcagctgactgtctatgtaagacccagagtgttcggggaccaaagagga ctgtcccaagataagcctgtggagatctctgtcctggctggggaggaggcaacccttccc tgtgaagcgaagagcttacctccaccaatcattacctgggccaaagatagccagctcatc tctccgttttctccaagacacacgttcctgccttctggctcaatgaagatcacagaaaca cgcatttcagacagtgggatgtatctgtgtgtggccacaaatattgctgggaatgtgact caatccgttaaattaagcgtccatgttcctccaaaaatacagcatggaaatagacaccta aaagtccaagtcggccagagagtggacatcccgtgcaatgcccatgggtctcctcctccc gtcatcacctggtttaaaagtggaaggcccatgccgttcaatggagtgcagcatcctggt agcccagatggaatgctgaccattgagcagaccacactctcagatgctggcacatacaca tgcactgccacaaacatagccggaagtgatgaagcagaggtcaccttgcatgtccaagaa ccacccacagtggaagacctgcaacctccctttaacactccgttccaagaacggttggcc aatcagcgcatggcatttccatgccctgcaaaaggtactcctaaaccaaccatcaagtgg ttacacaatggtaaagaggtgacagggcaggagcctggtgtctctatcttggaagatgga gcgctattggtaatcgcttctgttacaccactcaacaatggcgagtacatctgtgtggcc gtcaacgaagccgggaccacagaaaggaaatacaacctcagagttcacgttccaccagta attaaagataaagaacatgtgagcaatgtgtccgtgttggtaaaccaactggccagcctc tactgtgaagtagaaggaactccgtccccggtcataatgtggtataaggatgacatccag gtgacagaaagcagcactgttcagatcgtgaataatggaaagattctaaaactcttcaag gcgtctgcagaggataccggaagatactcctgcaaagcgattaatattgcaggaacctct cagaaggactttagtgtgaatgtactagttccacccagcatacaaggtgccggctcccca aatgaagtctcagttgttcttaaccacaacatcaccctacagtgcccggtcagaggcact ccctttccggctattcactggttcaaggatggcaagcctttatttttgggggatcctaac attgaactctcagacagaggacagaatttacatctgagaaatgcacggagaagtgacaag gggcgctaccaatgttctgtgtccaatgcagctggcaagcaagccaaggatataaagctc actctctacgttccacctagtattaaaggaggcaatgtcaccacagaaatatcggcattg ctcaacagcgtagttaaactggaatgtgagacgcgggggcttcctgtgcctgccattact tggtataaggatggccaggtggtcacatccagctcacaagcactttatattgacaaagga caatttctccacatcccgagagcacaagtctctgactcagcaacgtatacatgtcacgca tccaatgttgctggaacagccgaaaaatcattccatgttgacatctatgtccctccaata attgaaggtgacttgaccactccttcaagtaagcaggtcgttgttggtcagtcattggtc ctggagtgtaaagctgttggcaaccctccccccgtccttacttggttaaaagatggcgtg cctgtgaaagccagcgacaacatccacatagaagctggtgggaagaaactcgaaatcttg agtgccctagaagttgataggggacaatacatatgtgtggctaccagtgtggcaggagag cgggaaatcaagtatgaagttgatgtcttggtgccaccggctgtggaaggaggagatgag acatcttacttcattgtgctggcaaataacttactggagctagactgtcaggtctccggc tctcccccaccaactatcatgtggctaaaaggcggtcagttaattgatgaacgagatgga ttcaagatcttactaagtggacgcaaactggttattgctcaggctcaagtgtcagacaca ggcctgtaccagtgtgtggcaacaaacgttgcaggggatcgcaggaaggagttcgaagtg acagtgcacgttcctccaaccatcaagtcctcagaccttcctgagaagactgtggtgaga tacaagccagtcagcttgcagtgcatagccaacggcatcccaaacccatccatcacatgg ttgaaggatgaccagcctgtgaacactgccccaggaaacctcagaatacagtcttctggt agagttctacagattgccaaggctcttttggaagacgctggtagatacacatgcgtggct accaatgcagctggagaagcacatcagcacacccaattgcatgtgcatgaaccccccagc ctggatgatggcgggaagatgctgaacgagagcgtggtggtgaacaaccccattcagctg gagtgtaaagccacaggcagtcctgttcctgttctcacatggtacaaagacagccatcca ctcgcaggctccacaagtgcaaccttcctgaagagagggcagatccttgagattggaagt gctcagatctcagatgctggcatctacaaatgtgtagccatcaactctgctggagctaca gaattgttttacagcctacaagttcatgtgcctccttcgatctcagggagcagttccatg gtggaggtggtggtgaacaatctagcaaggttagaatgtgaagccaggggcatccctgcc cccagtctgacctggttgaaagatgggagtccagtctctagcttctctaatggaatacag gttctctcagggggtcgcatcttggcactgaccagtgcccaaatgagtgacacaggaagg tacacttgcgtggccgtgaatgctgctggggagaaacaaagggactttgacctcagagta tatgctccacccaatattatgggagaagaacagaatgtctctgtcctcattagccaaact gtggagttattttgtcaaagtgatgctgttcccccacctactctgatgtggttcaaggat ggccgccctctgctgaagagaccgggtctcagtatctctgaaaatggaagtgtgcttatg attgaagatgctcaggccggagacactggtcgatacacctgtgaagcgacaaatgttgct gggaaaacagagaaaaactacaacgttaacatctgggtacctcctagtatttatggctct gatgagctcgtgcaactcacagccattgaagggaatcttatcactctcctatgtgaatca agtggaattccacccccaaatcttacttggaaaaagaaaggttctctggtgttggctgac gctgcaggacgtgttcacattttatctggtggccgacggttacaaatttcaattgctgag aaagcagatgcaggactctacacgtgtgtggcatccaacgtggctggcattgcaaagaaa gagtacaaccttcaagtgtatatccgaccatcaatagccaacagtggcagtcaccgccct gagattactgtcatccgtgggagaagtatttccttggaatgtgaggtgcagggtattcct cagccaacagtgacctggatgaaagatggccgccccttgtccaagggaaaaggagtggaa atcctggatgaaggccgcgttcttcagctgaagaatgttcacgtttctgacacaggccgt tatgtgtgcgttgctgtgaatgtagcaggaatgactgacaaaagatatgacttaagtgtc cacgtccctccgagcatcatcgggaaccacggagtccctgagaacatcagtgtggtggaa aagagttctgtatccctgacctgtgaagcctccggcatccccctgccttccataacctgg ctgaaggatggttggcctgtcagccttggcagctctgtgaagattctctcaggaggcagg atgctgcggttgatgcagaccagaccagaagatgctggccagtatacatgtattgtaagg aatgcagctggtgaagacaggaaaatgtttggactttcagtattagttcctcctcacatt gtgggtgacaacacattggaagatataaagattaaagagaaacagagtgttacactgact tgtgaagtgagagggaatcctgtgccacagatcacatggcacaaagacggacagcttctc caggaagacgaagtacaccacatgatgtctggaggccgttttcttcagatcaccaatgct caagtgtcccacacaggacgatacacgtgtctggcctctaatatagctggtgacaaaagc aaaagtttcagtctcaatgtgtttgtatctcctacaattgctggtgtagacagtgatggc agccccgaagacgttattgtcatccttaacagccccacttctctagtgtgtgaggcatat tcctatcccccggccaccatcacctggttcaaggacggcgcgcctttagaatccagccgg aaccttcgcatccttccaggaggccgtactctgcagatcctaaacgcacaggaagacaat gccggaagatactcatgtgtggccactaatgaggctggggagatgataaagcactacgaa gtgaaggtctacattccgcccatcatcaagaaaggggaccttttggggacgggtctttcc ccgaaggaggtgaagatcagagtgaacagcagcctgactttggagtgtgaggcttacgcg attccatctgcctccctccgctggtacaaggacggacagccccttaaatcagatcatcat gttaacatcgctgaaaatgggcacactcttcaaatcaaggaagctcagatatcagacacc gggagatacacctgtgtggcctctaacctcgcaggcgaagatgagttggattttgatgtg aatatccaagttcctccaagttttcagaaactctgggaaataggaaacatgttagacacc ggcaggagtggagaagccaaagacgtgatcatcaacaaccctatttctctgcactgtgag acaaacgctgctcctccaccaacccttacatggtacaaagatggccgacctctgacctcc agtgacagagtgttgattttgccaggaggacgagtgctgcagattccccgggctaaagta gaagatgccgggcggtacacgtgtgtggccgtgaatgaagccggggaagactcccttcag tatgacatccatgtgctcttgccaccagttatcaagggagcaaacagtgatcttccggaa gaggtcaccgtgctggtgaacaagagtgcacagatggaatgttcatccagcggtagccca gcaccaaggaatttctggcaaaaagatggacagcccttgctagaagatgaacatcacaag ttcctatctgatggcagggttcttcagattctaaatgctcaaataacagataccgggagg tatgtgtgtgttgctgagaacacagctgggagtgccaagaaatactttaacctcaacgtt catgttcctccaagtgtcattggtcctaaccatgaacatctctctgtggttgtgaaccat ttcatctctttgacctgtgaagtttctgggttcccccctcctgacctcaactggctcaag aatgaacagcccatcaagccaaacactaatgttctcattgtgcctggtggtcgaactcta cagattattcgggccaaggtatctgatggcggtgaatatacctgcgtcgctatcaaccaa gccggagaaagcaagaaaaaggtttccctgactgttcatgtacccccaagcattaaggat cacggcagcgagtctctgtctatagttaatgtaagagaggggacctcggtgtcattggaa tgcgagtcaaatgctgtgcccccgccagtcatcacctggtctaagaatgggcggatgata ccggattctagcaacgtggcgattttaactggtggacaaatgctacacatcaggcgagcc gaggtggctgacacaggccagtatgtatgtagagctataaatgtagcaggacgagatgat aaaaatttccacctcaatgtatatgtgccccccaccattgaagggcctgaaacagaagtc attgtggagacaatgagcaatccggtgacattgacttgcgatgccactgggatccctcct cccaccataacatggttaaagaaccacaagcccatagaaaactctgacccccttgaggct cacattttgtctggaggaagcaaactgcaaattgcccgacttcagcgttcaaaccgtgga aactacacgtgtgttgcatccaatatggagggaaaggctcagaaaaattatatcctttcc attcaggtccctccaagtgttgccggtgcggaagttccaagtgaagttagtgtccttctt ggggaaaatgtggagctggtctgtgatgcagatggcattcccatccctcgtctacagtgg cttagagacggaaaacccatagtgagtggtgaaacagaacgagtcagggtcaccacagat ggcagcacactaaatatttacagagccctcacatctgacatgggaaagtatacatgtgtg gctactaatcctgctggagaagaagaccgaatatttaacttgaatgtctatgttccacct aaaatccgaggtaataaggaggaggcagagaaactgatggctctggtagacacgtcacta aacatcgaatgcaaagccacggggacacctccaccgcagatcagctggctgaagaacggc cttcctctgcccatctcttcccacattcgcttgctgtcagcagggcaggccatcaggatc gtgagagctcaggtgtctgatgttgctgtgtatacttgtgtggcctccaatagagctggg atagatagtaagcgctacagccttcaagtctttgtgccaccgaatatggacaacgcaatg ggaacagaggaaatcacacttgtcaaaggcagttctacctctatgacgtgctttacagat ggagcccctacccctagcatgtcttggctcagagacggccagcctctggcgcttgatgct catctgaccatcggcactcaggggatggtccttcagctcatcaaggcagacacggaagat actggaaagtacacctgcgttgcctcaaatgaagctggagaagtcagcaagcattttgtc ctgaaagtcctagaaccgcctcacatcaatggatctgaagggcctggagaggtatccgta attgtaaataacccacttgaactgtcctgcattgcttctggaatccctgcccctaagatt tcctggatgaaagatggccggccctttctacagacagagcaagtgcagactctagaagga ggagctattcttcgagtgtccagtgcgcaggtggaggacacaggaagatacacctgcctg gcatccagtcctgcaggggacgatgataaagaatatctagtgagagtacacgtgcctcct aacattgctggagtggatgaagcccaggacttcaccgtgttaaggaacaggcaggtgaca ttggaatgcaagtccgacgcagtgcctccacctgtgatcatgtggctcaaaaatggggag cagttacaggcaacacctcgagtaagaatcctgtctggaggcagatacttgcaaattaat aatgcagacctgggagacacggccaattatacctgtgtcgccagcaacatcgcaggaaag actacaagagaatttatcctcactgtaaatgttcctccaagcatcagtggtggtccccag agccttgtcactctcttaaataagtcaattgccctggaatgccttgctgaaggcgtgcca tcacccaggataacatggagaaaggacggtgttgttctagctgagagccatgcaagatac tccatcttggaaaatggatttcttcacattcagtcagcacatatcacagataccggacgg tatttgtgtatggcaaccaatgtggctggaacagaccgtaggcgaatagatttacaagtc catgttcctccctccattgctgcgggtcctaccaatgtaacagtgaccgtgaacgtccaa actactttggcttgtgaagctactgggataccaaagccatcaatcaactggagaaaagac ggacatctgcttaatgtagatcaaaatcagaattcatacagactcctttcctcaggttca ctcatcatcatttccccctctgtggatgacactgccagttacgagtgcaccgtgacaagt gatgctggagaggacaagagaacagtggacctcactgtccaagttcctcccaccatagct gatgagcctatggatttcctggtaaccagacaggccccagcagtcatgacctgctctgct tctggagttccacttccctcaattcactggaccaaaaatggcataagactgcttcccagg ggagatggctatcggattctgtcctcaggagccattgagatatctgctgcccagttaaac cacgcaggaagatacacttgcattgctcggaatgcagcaggctcagtacaccgacatgta acccttcgtgttcaagagcctccattcattcagccccaaccaagtgaactggatgtcatt ctaaacaaccccatcttactaccgtgtgaagcaacaggcatacccacgccatttataact tggcaaaaagaaggcatcaacgtcattacctcaggcaagagccttgctgttcttcccagt ggcagcttacagatctccagagctgttcagggggatgctggcacctacatgtgtgtggct caaaacccagctggtacagccttgggcaagatcaagctgaatgtacaagttcctccagcc attagttctcatcaaaaggaatatgttgttactatggataagcctgtctccctcttgtgt gagacagagggctccccaccacctgacatcacctggcataaagatgggcatgctctcact gaatccatccgccagcgcatcctgaactcaggagctctgcagatagcatttgctcaaccc gatgatgctggtcagtacacatgcatggccgctaacatggcgggatcaagcagcatgagc accacactcaccgtccatgtaccacctaggatccaaagcacagaagtacactacaccgtc aacgagaactctcaagttgttctcccgtgtgtcgctgatggaatccccacgcctgcaatt cactgggaaagagacagcgttcttctagccaacttgttagggaagtacactgcccagcca tatggagaactcgtcttggaaaatgttgtgctggaagatgctggcacctacacatgtgtt gctaacaatgctgctggtgaagatacacatactgtgaccctgactgttcatgcccttccc acttttaccgaacttcctggagacctgtcattaaataaaggagagcagctacggctaagt tgtaaagccgttggcattccattgcccaaactaacgtggaccttcaacaacaatattatt ccagcccactttgacagcgtcaatggacacagtgaacttgttattgagaaggtgtcaaag gaggactcgggcacttacgtgtgtacagcagagaacagcgttggctttgtgaaagcgatt ggatttgtttatgtgaaagagcccccagtcttcaaaggtgattacccctctaactggatt gaaccactcggcgggaatgcaatcctaaattgtgaagtgaaaggagaccctgccccaacc atccaatggagtcgcaagggggctgacgtagagattagccacaggatccgacaactgggt aatggctccttggctatctacggtaccgtgaatgaagacgctggtgactatacatgtgtt gctgccaatgaggccggggtggtagagcgcagtatgagtctgactctgcaaagttctccc atgatcactcttgagcctgtggaaaccattgtggatgccggtggcagagtcacattggat tgtcaagcagctggtgaacctcagccaaccatcacatggtcccgtcaagggcgccccatc ccctgggataaccgacttaccatgctgcctaatagttcattatacatcgctgctgctcgc aaggaagacacctctgaatatgagtgtgttgcccgaaacttgatgggctctgtccttgtc agagtgcccgtcatagtccaggtgcatggtgggttttcgttgtggtctgcctggaggtcc tgcagtgtcacctgtggaaaaggcatccaaaagaggagcaggctatgcaacaaccctcct ccagccaatggagggaggccatgccaaggctcagagtcagaagcacgacagtgtcaaaat aagttgtgtccagtggatggtcactggtcagaatggagcttctgggaagaatgctcaaga agctgtgggcatggcaaccaaactaggacgagaacttgcagtaacccaccggctcagcat ggtgggcggccatgtgaggggtatgctgtggaaaccatcatgtgtaacattcggccttgc ccagtccatggtgtgtggaatgcttggcaaccttggggttcgtgcagcaaaagctgtgga aaaggcagtcagacaagaacaagactttgcaacagcccgccaccgtcatttggtggggcc tactgcaatggagcagaaacccagatgcaagtctgcaatgagagacactgtccagtggat ggcaagtgggcagcttggaccagttggagtacctgcactgtatcctgtggaggaggtacc aggaagagaacaagggactgttctgacccagtgccacagtatggaggaaacaaatgcgaa gggactggtgtccagagtgacttttgcaatagtgacccttgtccaacccatggcaactgg agcccttggagtggctgggggatgtgcagtcggacatgcaatggagggcagatgagacgg taccgcacatgtgataatccacggccctccaatggaggaagagcctgtgggggtccagat acccagatccagaggtgtaatactgacatgtgtcctgtggatggaagttggggaacatgg catagttggagtcattgttctgtctcttgcgggggaggtgaaagaactcgaaagcggtta tgtgacaatcctgtgccctctaaaagtggccgttcctgtccaggagatgccacccaagtc tccagatgcaacatgcaggcttgtccgggtggaccccaacgagccagagggagtgttatt gggaatattaatgatattgagtttggaatcgctttccttaatgccacaataacagatagc cctaactctgatacaagaataatacaggccacgattaccaatgtgcctcgcagtctgggt ccagcaatgagaaagatcatttctatcctaaatcccatttactggaccacagcaaaggaa ataggggaagcagtcaatggctttaccctcactaacgcagtcttcaaaagagagacgcaa gtggaatttgcaactggagaggtcttgaggatgacacatgtggctcggggcttagattcc gacggcgcattgctgcttgacgtcattgtgagtggccatgtcctgcagctccactcacct gctgaagttagtgtgaaggattacacagaggactacattcaaacaggacctgggcagctc tacgcctactcaacccggctgttcaccatcgatggcatcagtgtcccctatacatggaac cacaccattttctatgatcaggcctgggggaaaatgcctttcttagtagaaacacttcat gcatcttctgtagaatctgactacaaccaactagaggagacactgggtttcaaaatccac gcttcaatctccaaaggagatcgcagtaaccagtgcccctctggttttatcttagactca gctggacccttctgtgctgatgaggatgaatgcacagctgggaacccctgctctcatacc tgccacaatgccataggagcctattattgctcctgtcccaaaggcctcaccatagctgcc gatgggagaacctgtcaagacattgatgagtgtgctttgggtggacatacctgtcatgct ggtcaagactgtgacaataccattggatcctatcgctgtgtggtccactgcggaacaggc ttccggagaacctctgatgggctgagctgtcaagatattaatgaatgtcaggaatccagc ccctgccaccagcggtgtttcaatgtcataggaagtttccactgtggctgtgaagctggc tatcaactcaaaggcagaaagtgcatcgatgtgaacgaatgtagacagagcgtgtgcaga ccagaccagcactgtaagaacacccgcggtggctacaagtgcattgatctctgtccaagt ggaatgaccaaggctgagaatgggacctgcattgacattgatgagtgcaaagatgggacc caccaatgcagatataaccaaatatgtgagaacacgagaggcagctaccggtgtgcatgc ccaaggggttatcggtctcaaggagttggaagaccctgcgttgacattaatgaatgtgac caagtacctaaaccttgtgcacatcagtgctccaacagccccggcagcttcaagtgtatc tgtctgccaggacaacatttattaggggatgggaaatcttgcgctggattggagaggctg tcgagttatggcactcagtacagtagctatgaccttgagcggttctcccctgtgagaagt ggctatcaacctcggcagcataccagacagcagtcacagctctacagctcctactcagag tataggaacagcagagcatctttctccaggagtagaaggactattaggaaaacttgccct gaaggctctgaggcaaaccatgaaacatgtgtagatattgatgaatgtcaaaacagagat acttgccaacatgagtgtaaaaacacgatcggaagctaccagtgcgtctgcccaccgggt tatcgactcatgctcaatgggaaaacatgccaagatgtcgatgagtgcttggagcagaat gtacgctgtgggccgaatcgcatgtgtttcaacatgagaggaagctatcagtgcatcgac acaccctgtccacccaactaccaacgagatcctgttttggggttctgcctcaagaactgc ccacccaatgacttggaatgcaccttgagcccctatgccttggaatataaacttgtctcc ctcccatttggaatagctgccaatcaagatttaatccggctggttgcatacacacaggat ggagtgatgcatcccaggacaactttcctcatggtagatgaggaaccagctgtccctttt gccttaagggatgaaaacctgaaaggagtcgtgtacactacacgtccactacgagaggca gagacctaccgcatgaaggtgcgggctttatcctacagtgccaacgggaccattgagtat cagactacattcatagtttatatagctgtgtctgcctatccatactag

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