Rattus norvegicus (rat): 290646
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Entry
290646 CDS
T01003
Symbol
Pde4c
Name
(RefSeq) 3',5'-cyclic-AMP phosphodiesterase 4C
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00230
Purine metabolism
rno01100
Metabolic pathways
rno04024
cAMP signaling pathway
rno04928
Parathyroid hormone synthesis, secretion and action
rno05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
290646 (Pde4c)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
290646 (Pde4c)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
290646 (Pde4c)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
290646 (Pde4c)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
290646 (Pde4c)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Emfourin
Motif
Other DBs
NCBI-GeneID:
290646
NCBI-ProteinID:
NP_001263694
RGD:
727918
Ensembl:
ENSRNOG00000019518
UniProt:
A6KA07
G3V8J8
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All DBs
Position
16:complement(18724703..18745528)
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AA seq
671 aa
AA seq
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MRRSGTTLSFLLTERVREPVDSGVAPVSHLGGGVILRRFSGTLLLPPLSSRLGSSGEAES
AAPVVFTIGSRGTERSHGSAQSSFDLENGLPSGRGPLDAQSGSSLGRALQPPVHHGQRRE
SFLYRSDSDHEPSPKAVSRTSSAASDLHGEDMIVTPFAQVLASLRTVRSNVAALAHGAGS
ATRQALLGTPPQSSQQAAPAEESGLQLAQETLEELDWCLEQLETLQTRRSVGEMASNKFK
RMLNRELTHLSETSRSGNQVSEYISQTFLDQQAEVELPAPPTEDHPWPMAQITGLRKSCH
TSLPTAAIPRFGVQTDQEEQLAKELEDTNKWGFDVFKVAELSGNRPLTAVIFSVLQERDL
LKTFQIPADTLLRYLLTLEGHYHSNVAYHNSIHAADVVQSAHVLLGTPALEAVFTDLEVL
AAIFACAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFKLLQGENCDIFQN
LSTKQKLSLRRMVIDMVLATDMSKHMSLLADLKTMVETKKVTSLGVLLLDNYSDRIQVLQ
SLVHCADLSNPAKPLPLYRQWTERIMAEFFQQGDRERESGLDISPMCDKHTASVEKSQVG
FIDYIAHPLWETWADLVHPDAQELLDTLEDNREWYQSRVPCSPPHAIGPDRFKFELTLEE
TEEEEEEDERH
NT seq
2016 nt
NT seq
+upstream
nt +downstream
nt
atgaggcggagtggcacgaccctgtccttcctgttgactgagcgagtccgagagccagtg
gattctggagtggcccctgtcagccacctaggtgggggtgtgatcctgagacggttctca
gggaccctgctgctgcctccgctgtccagccgactcgggtcctctggggaggcggagtct
gctgcccccgtggttttcaccatcggatcccgagggacagagagaagccatggctcagct
cagagcagctttgacctggaaaatgggctcccgagcggcaggggtcccctggatgctcag
tccgggtcgagtctcggccgcgccctccaaccccctgtgcatcacggccagcggcgcgag
tccttcctgtaccgctcggacagtgaccatgagccttcacccaaggctgtgtcccggacc
tcctcggcggccagcgacctacatggagaagacatgattgtcacacccttcgcccaggtc
ctggccagtctcaggacggtccgtagcaacgtggctgcccttgcacatggcgcgggcagt
gccactaggcaggcgctcctggggacccctccgcagagcagccaacaggccgccccagca
gaggaatctgggctgcagctggcgcaggagacactggaggagctggactggtgcctggag
cagctggagacactgcagactcgtcgctcggtgggcgagatggcttctaacaagttcaag
cgcatgctcaaccgtgagttgacccacctgtcggaaaccagccgctcagggaaccaagtg
tcagagtacatctcgcagactttcctggaccagcaggctgaggtggagctgccggctccg
cccacggaagaccacccatggcccatggcccagatcactgggctgcggaagtcttgccac
accagccttcctacagctgccatcccgcgctttggggtccagacagaccaggaggagcag
ctggctaaggagcttgaagacaccaacaaatggggattcgatgtgtttaaagtggctgag
ctgagtgggaaccggcccctcactgctgttatcttcagcgttctccaggaacgggacctg
ctcaagacgttccagatcccggcggacacgctgctgaggtacctgctgaccctcgaaggg
cactaccactccaacgtggcgtaccacaacagcatacatgctgccgacgtggtgcaatcc
gcgcacgtgttgctgggcaccccagccctggaggctgtgttcacggacctagaagtcttg
gccgccatctttgcgtgcgctatacacgatgtagaccacccaggtgtctccaaccagttt
ctcatcaacaccaactcggagctggcactgatgtacaatgactcatcggtgctagagaac
catcacctcgcggtaggcttcaagctcctgcagggggaaaactgcgacatcttccagaac
ctcagcaccaagcagaaactgagtctgcgcaggatggtcatagacatggtactggccaca
gacatgtccaagcacatgagcctcctggctgacctcaagaccatggtggagaccaagaaa
gtgactagccttggcgtcctgctcttggacaactactctgaccgcatccaggtcctccag
agcctggtgcactgcgccgacctcagcaaccctgccaagccactacccctctaccgccag
tggacggagcgcatcatggctgagttcttccagcagggtgaccgggaacgtgagtcgggc
ttggacatcagccccatgtgcgacaagcacacagcctcggtggagaaatcccaggtggga
ttcattgactacatcgctcacccattgtgggaaacttgggccgacctggtgcaccccgat
gcccaggagctgctggataccttggaagacaacagagagtggtatcagagtagggttccc
tgcagccctccacacgccattggccctgacaggttcaagtttgagctgaccctggaggag
acagaggaagaggaggaagaggatgaaaggcactga
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