Rattus norvegicus (rat): 29263
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Entry
29263 CDS
T01003
Symbol
Acvr2a
Name
(RefSeq) activin receptor type-2A precursor
KO
K04670
activin receptor type-2A [EC:
2.7.11.30
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04060
Cytokine-cytokine receptor interaction
rno04350
TGF-beta signaling pathway
rno04550
Signaling pathways regulating pluripotency of stem cells
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
29263 (Acvr2a)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
29263 (Acvr2a)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
29263 (Acvr2a)
09160 Human Diseases
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
29263 (Acvr2a)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
29263 (Acvr2a)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
29263 (Acvr2a)
Protein kinases [BR:
rno01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
29263 (Acvr2a)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_fungal
Activin_recp
Motif
Other DBs
NCBI-GeneID:
29263
NCBI-ProteinID:
NP_113759
RGD:
70911
Ensembl:
ENSRNOG00000005334
Vega:
OTTRNOG00000002257
UniProt:
P38444
A6JEZ1
Structure
PDB
PDBj
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All DBs
Position
3:53614143..53701933
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AA seq
513 aa
AA seq
DB search
MGAAAKLAFAVFLISCSSGAILGRSETQECLFFNANWERDRTNQTGVEPCYGDKDKRRHC
FATWKNISGSIEIVKQGCWLDDINCYDRTDCIEKKDSPEVYFCCCEGNMCNEKFSYFPEM
EVTQPTSNPVTPKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYPPVLVPTQDPGP
PPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPG
MKHENILQFIGAEKRGTSVDVDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGL
AYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQV
GTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYMLPFEEEIG
QHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERIT
QMQRLTNIITTEDIVTVVTMVTNVDFPPKESSL
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgggagctgctgcaaagttggcgttcgccgtctttcttatctcttgctcttcaggtgct
atacttggcagatcggaaactcaggagtgtcttttctttaatgctaattgggaaagagac
agaaccaatcagactggtgttgagccttgctatggtgataaagacaaacgacgacattgt
tttgctacctggaagaatatttctggttccattgaaatagtaaagcaaggttgttggctg
gatgatatcaactgctatgacaggactgattgtatagaaaaaaaagacagccctgaagtg
tacttttgttgctgtgagggcaatatgtgtaatgaaaagttctcttattttccggagatg
gaagtcacacagcccacatcaaatcctgttaccccgaaaccaccctactacaacatcctg
ctgtattccttggtaccacttatgttaattgcggggattgtcatttgtgcgttttgggtg
tacagacatcacaagatggcctaccctcctgtacttgttcctactcaggaccctggacca
cctccaccttccccattactagggttgaagccattgcagctattggaagtgaaagcaagg
ggaagatttggttgtgtctggaaagcccagttgctcaatgagtatgtggctgtcaaaata
tttccgatacaggacaaacagtcctggcagaatgaatatgaagtctatagtttacctggt
atgaagcatgaaaacatactacagttcattggtgcagagaaaagaggcaccagtgttgat
gtggacctgtggctaatcacggcttttcatgaaaagggctcactgtcagactttcttaag
gctaatgtggtctcttggaatgaactttgtcatattgcagaaaccatggctagaggattg
gcatatttacatgaggatatacctggcttaaaagatggccacaagcctgcaatatctcac
agggacataaaaagtaaaaatgtgctgttgaaaaacaatctgacagcttgcattgctgac
tttgggttggccttaaagtttgaggctggcaagtctgcaggtgacacccatggccaggtt
ggtacccggaggtatatggctccagaggtgttagagggtgctataaacttccaaagggac
gcatttctgaggatagatatgtacgccatgggattagtcctgtgggaactggcttctcgt
tgtactgctgcagatggacctgtagatgagtacatgttgccatttgaggaggaaattggc
cagcatccatctcttgaagatatgcaggaagttgttgtgcataaaaaaaagaggcccgtt
ttaagagattattggcagaaacacgcaggaatggcaatgctctgtgaaacgatagaagaa
tgctgggatcatgatgcagaagccaggttatcagctggatgtgtaggtgaaagaattact
cagatgcaaagactaacaaatataattactacagaggacattgtaacagtggtcacaatg
gtgacaaatgttgactttcctcccaaagaatctagtctatga
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