Rattus norvegicus (rat): 293621 Help Entry 293621            CDS       T01003                                  Symbol Hras Name (RefSeq) GTPase HRas   KO K02833   GTPase HRas Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno01522   Endocrine resistance rno04010   MAPK signaling pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04015   Rap1 signaling pathway rno04062   Chemokine signaling pathway rno04068   FoxO signaling pathway rno04071   Sphingolipid signaling pathway rno04072   Phospholipase D signaling pathway rno04137   Mitophagy - animal rno04140   Autophagy - animal rno04144   Endocytosis rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04210   Apoptosis rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04218   Cellular senescence rno04360   Axon guidance rno04370   VEGF signaling pathway rno04371   Apelin signaling pathway rno04510   Focal adhesion rno04540   Gap junction rno04550   Signaling pathways regulating pluripotency of stem cells rno04625   C-type lectin receptor signaling pathway rno04630   JAK-STAT signaling pathway rno04650   Natural killer cell mediated cytotoxicity rno04660   T cell receptor signaling pathway rno04662   B cell receptor signaling pathway rno04664   Fc epsilon RI signaling pathway rno04714   Thermogenesis rno04720   Long-term potentiation rno04722   Neurotrophin signaling pathway rno04725   Cholinergic synapse rno04726   Serotonergic synapse rno04730   Long-term depression rno04810   Regulation of actin cytoskeleton rno04910   Insulin signaling pathway rno04912   GnRH signaling pathway rno04915   Estrogen signaling pathway rno04916   Melanogenesis rno04917   Prolactin signaling pathway rno04919   Thyroid hormone signaling pathway rno04921   Oxytocin signaling pathway rno04926   Relaxin signaling pathway rno04929   GnRH secretion rno04933   AGE-RAGE signaling pathway in diabetic complications rno04935   Growth hormone synthesis, secretion and action rno05010   Alzheimer disease rno05022   Pathways of neurodegeneration - multiple diseases rno05034   Alcoholism rno05132   Salmonella infection rno05160   Hepatitis C rno05161   Hepatitis B rno05163   Human cytomegalovirus infection rno05165   Human papillomavirus infection rno05166   Human T-cell leukemia virus 1 infection rno05167   Kaposi sarcoma-associated herpesvirus infection rno05170   Human immunodeficiency virus 1 infection rno05200   Pathways in cancer rno05203   Viral carcinogenesis rno05205   Proteoglycans in cancer rno05206   MicroRNAs in cancer rno05207   Chemical carcinogenesis - receptor activation rno05208   Chemical carcinogenesis - reactive oxygen species rno05210   Colorectal cancer rno05211   Renal cell carcinoma rno05213   Endometrial cancer rno05214   Glioma rno05215   Prostate cancer rno05216   Thyroid cancer rno05218   Melanoma rno05219   Bladder cancer rno05220   Chronic myeloid leukemia rno05221   Acute myeloid leukemia rno05223   Non-small cell lung cancer rno05224   Breast cancer rno05225   Hepatocellular carcinoma rno05226   Gastric cancer rno05230   Central carbon metabolism in cancer rno05231   Choline metabolism in cancer rno05235   PD-L1 expression and PD-1 checkpoint pathway in cancer rno05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     293621 (Hras)    04012 ErbB signaling pathway     293621 (Hras)    04014 Ras signaling pathway     293621 (Hras)    04015 Rap1 signaling pathway     293621 (Hras)    04370 VEGF signaling pathway     293621 (Hras)    04371 Apelin signaling pathway     293621 (Hras)    04630 JAK-STAT signaling pathway     293621 (Hras)    04068 FoxO signaling pathway     293621 (Hras)    04072 Phospholipase D signaling pathway     293621 (Hras)    04071 Sphingolipid signaling pathway     293621 (Hras)    04151 PI3K-Akt signaling pathway     293621 (Hras)    04150 mTOR signaling pathway     293621 (Hras)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     293621 (Hras)    04140 Autophagy - animal     293621 (Hras)    04137 Mitophagy - animal     293621 (Hras)   09143 Cell growth and death    04210 Apoptosis     293621 (Hras)    04218 Cellular senescence     293621 (Hras)   09144 Cellular community - eukaryotes    04510 Focal adhesion     293621 (Hras)    04540 Gap junction     293621 (Hras)    04550 Signaling pathways regulating pluripotency of stem cells     293621 (Hras)   09142 Cell motility    04810 Regulation of actin cytoskeleton     293621 (Hras)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     293621 (Hras)    04650 Natural killer cell mediated cytotoxicity     293621 (Hras)    04660 T cell receptor signaling pathway     293621 (Hras)    04662 B cell receptor signaling pathway     293621 (Hras)    04664 Fc epsilon RI signaling pathway     293621 (Hras)    04062 Chemokine signaling pathway     293621 (Hras)   09152 Endocrine system    04910 Insulin signaling pathway     293621 (Hras)    04929 GnRH secretion     293621 (Hras)    04912 GnRH signaling pathway     293621 (Hras)    04915 Estrogen signaling pathway     293621 (Hras)    04917 Prolactin signaling pathway     293621 (Hras)    04921 Oxytocin signaling pathway     293621 (Hras)    04926 Relaxin signaling pathway     293621 (Hras)    04935 Growth hormone synthesis, secretion and action     293621 (Hras)    04919 Thyroid hormone signaling pathway     293621 (Hras)    04916 Melanogenesis     293621 (Hras)   09156 Nervous system    04725 Cholinergic synapse     293621 (Hras)    04726 Serotonergic synapse     293621 (Hras)    04720 Long-term potentiation     293621 (Hras)    04730 Long-term depression     293621 (Hras)    04722 Neurotrophin signaling pathway     293621 (Hras)   09158 Development and regeneration    04360 Axon guidance     293621 (Hras)   09149 Aging    04211 Longevity regulating pathway     293621 (Hras)    04213 Longevity regulating pathway - multiple species     293621 (Hras)   09159 Environmental adaptation    04714 Thermogenesis     293621 (Hras)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     293621 (Hras)    05206 MicroRNAs in cancer     293621 (Hras)    05205 Proteoglycans in cancer     293621 (Hras)    05207 Chemical carcinogenesis - receptor activation     293621 (Hras)    05208 Chemical carcinogenesis - reactive oxygen species     293621 (Hras)    05203 Viral carcinogenesis     293621 (Hras)    05230 Central carbon metabolism in cancer     293621 (Hras)    05231 Choline metabolism in cancer     293621 (Hras)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     293621 (Hras)   09162 Cancer: specific types    05210 Colorectal cancer     293621 (Hras)    05225 Hepatocellular carcinoma     293621 (Hras)    05226 Gastric cancer     293621 (Hras)    05214 Glioma     293621 (Hras)    05216 Thyroid cancer     293621 (Hras)    05221 Acute myeloid leukemia     293621 (Hras)    05220 Chronic myeloid leukemia     293621 (Hras)    05218 Melanoma     293621 (Hras)    05211 Renal cell carcinoma     293621 (Hras)    05219 Bladder cancer     293621 (Hras)    05215 Prostate cancer     293621 (Hras)    05213 Endometrial cancer     293621 (Hras)    05224 Breast cancer     293621 (Hras)    05223 Non-small cell lung cancer     293621 (Hras)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     293621 (Hras)    05170 Human immunodeficiency virus 1 infection     293621 (Hras)    05161 Hepatitis B     293621 (Hras)    05160 Hepatitis C     293621 (Hras)    05163 Human cytomegalovirus infection     293621 (Hras)    05167 Kaposi sarcoma-associated herpesvirus infection     293621 (Hras)    05165 Human papillomavirus infection     293621 (Hras)   09171 Infectious disease: bacterial    05132 Salmonella infection     293621 (Hras)   09164 Neurodegenerative disease    05010 Alzheimer disease     293621 (Hras)    05022 Pathways of neurodegeneration - multiple diseases     293621 (Hras)   09165 Substance dependence    05034 Alcoholism     293621 (Hras)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     293621 (Hras)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     293621 (Hras)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     293621 (Hras)    01522 Endocrine resistance     293621 (Hras)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     293621 (Hras)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:rno04147]     293621 (Hras)    04031 GTP-binding proteins [BR:rno04031]     293621 (Hras) Membrane trafficking [BR:rno04131]  Exocytosis   Small GTPases and associated proteins    Other small GTPases and associated proteins     293621 (Hras)  Endocytosis   Macropinocytosis    Ras GTPases     293621 (Hras) Exosome [BR:rno04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    293621 (Hras)   Exosomal proteins of colorectal cancer cells    293621 (Hras) GTP-binding proteins [BR:rno04031]  Small (monomeric) G-proteins   Ras Family    Ras [OT]     293621 (Hras) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N AAA_16 Motif Other DBs NCBI-GeneID:  293621 NCBI-ProteinID:  NP_001091711 RGD:  2827 Ensembl:  ENSRNOG00000016611 UniProt:  P20171 A6HXQ6 Structure PDBPDBj LinkDB All DBs Position 1:complement(205712625..205729406) Genome browser AA seq 189 aa AA seqDB search MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG CMSCKCVLS NT seq 570 nt NT seq  +upstreamnt  +downstreamnt atgacagaatacaagcttgtggtggtgggcgctggaggcgtgggaaagagtgccctgacc atccagctgatccagaaccattttgtggacgagtatgatcccactatagaggactcctac cggaaacaggtagtcattgatggggagacgtgtttactggacatcttagacacagcaggt caagaagagtatagtgccatgcgggaccagtacatgcgcacaggggagggcttcctctgt gtatttgccatcaacaacaccaagtcctttgaagacatccatcagtacagggagcagatc aagcgggtgaaagattcagatgatgtgccaatggtgctggtgggcaacaagtgtgacctg gccgctcgcactgttgagtctcggcaggcccaggaccttgctcgcagctatggcatcccc tacattgaaacatcagccaagacccggcagggtgtggaggatgccttctacacactagta cgtgagattcggcagcataaactgcggaaactgaacccgcctgatgagagtggccctggc tgcatgagctgcaagtgtgtgctgtcctga

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