Rattus norvegicus (rat): 294924
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Entry
294924 CDS
T01003
Symbol
Mecom
Name
(RefSeq) histone-lysine N-methyltransferase MECOM
KO
K04462
[histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:
2.1.1.367
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno00310
Lysine degradation
rno01100
Metabolic pathways
rno04010
MAPK signaling pathway
rno05200
Pathways in cancer
rno05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
294924 (Mecom)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
294924 (Mecom)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
294924 (Mecom)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
294924 (Mecom)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
rno03000
]
294924 (Mecom)
03036 Chromosome and associated proteins [BR:
rno03036
]
294924 (Mecom)
Enzymes [BR:
rno01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.367 [histone H3]-lysine9 N-methyltransferase
294924 (Mecom)
Transcription factors [BR:
rno03000
]
Eukaryotic type
Zinc finger
Cys2His2 PRDM
294924 (Mecom)
Chromosome and associated proteins [BR:
rno03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
294924 (Mecom)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
zf-C2H2
zf-H2C2_2
zf-C2H2_4
PRDM2_PR
zf-C2H2_6
zf-C2H2_jaz
SET
zf-H2C2_5
zf-BED
C2CH-3rd_BIRD-IDD
Zap1_zf1
zf-C2H2_8
zf-C2HE
Motif
Other DBs
NCBI-GeneID:
294924
NCBI-ProteinID:
NP_001376211
RGD:
1310997
Ensembl:
ENSRNOG00000012645
LinkDB
All DBs
Position
2:114837815..115393052
Genome browser
AA seq
1242 aa
AA seq
DB search
MRSKGRARKLATSNECAYGNYPEIPLEEMPDAEDADGIANAPSLHIQEPCSPATSSESFT
PKEGSPYKAPIYIPDDIPIPDEFELRESTMPGAGLGIWTKRKIEIGEKFGPYMGEQRSDL
KDSSYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVA
DIAPGEELLLFMKSEEDPHEPMAPDIHEERQHRCEDCDQLFESKAELADHQKFPCSTPHS
AFSMVEEDLQQNLESESDLREIHGNQDCKECDRVFPDLQSLEKHMLSHTEEREYKCDQCP
KAFNWKSNLIRHQMSHDSGKHYECENCAKQVFTDPSNLQRHIRSQHVGARAHACPECGKT
FATSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFST
TSSLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMGHANPGLVDYFGTNRHP
AGLTFPTAPGFSLSFPGLFPSGLYHRPPLIPASSPVKGLSSTEQSNKCQSPLLTHPQILP
ATQDILKALSKHPPVGDNKPVELLPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETT
SGSDLESDLESDKEKCKENGKMFKDKVSPLQNLASINNKKEYSNHSVFSASVEEQTAVSG
AVNDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLR
SLPLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTSGSSKLPATPATSQDQPLDLS
MGSRSRASGTKLTEPRKNHVFGEKKGSNMETRPSSDGSLQHARPTPFFMDPIYRVEKRKL
TDPLEALKEKYLRPSPGFLFHPQFPLPDQRTWMSAIENMAEKLESFSGLKPEASELLQSV
PSMFSFRAPPNTLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDR
SFSISSNLQRHVRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSE
LESAGAILDDKEDAYFTEIRNFIGNSNHGSQSPRNMEERMNGSHFKDEKALATSQNSDLL
DDEEVEDEVLLDEEDEDNDIPGKPRKELGVTNLDEEIPEDDYEEAGALEMSCKVSPVRYK
EEDYKSGLSALDHIRHFTDSLKMREMEENQYTDAELSFGSSHVPEELKQPLHRKSKSQAY
AMMLSLSDKDALHPTSHGSSNVWHSMARAAAESSAIQSISHV
NT seq
3729 nt
NT seq
+upstream
nt +downstream
nt
atgagatccaaaggcagggcaaggaaactggccacaagtaatgagtgtgcttatggcaac
taccctgaaatacccttggaagaaatgccagatgccgaagatgcagatgggatagccaat
gctccctcccttcacatccaagagccatgctctcctgcgacatccagtgagtcatttact
cctaaggagggctcgccctacaaagcccccatctacatccccgatgacatccccattcct
gatgaattcgagcttcgagagtcaactatgcctggagcaggacttggaatatggaccaaa
aggaagattgaaataggagaaaagtttgggccatacatgggagagcagagatcagacctg
aaagattccagctatggatgggagatcttagatgagttttgcaatgtgaagttctgcata
gatgccagtcaaccagatgtaggaagctggctcaagtacatccgattcgctggctgctac
gatcagcacaaccttgttgcatgccagataaacgatcagatattctacagagtagtcgca
gacattgcgcctggggaggaactcctgctgttcatgaagagtgaagaggacccacatgag
cccatggcgcctgacatccatgaagaacggcagcaccgctgtgaggactgtgaccagctc
tttgaatccaaggctgagctggctgatcaccagaagttcccatgcagcacacctcactcg
gccttctccatggtggaggaggacttgcagcaaaacctggagagtgagagtgatctccga
gagatccatggcaaccaggactgtaaggaatgtgaccgagttttccccgatctacaaagc
ttggagaagcacatgttgtcacacactgaggagagggaatacaagtgtgatcagtgcccc
aaggcatttaactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaag
cactatgagtgtgaaaactgtgccaagcaggttttcacggaccctagcaaccttcagcga
cacattcgatctcagcatgttggtgcccgggctcatgcttgcccggagtgtggtaaaaca
tttgccacttcgtcaggcctcaaacaacacaagcacatccacagcagtgtgaagcccttt
atctgtgaggtctgccataaatcctatactcagttttcaaacctttgtcgtcataagcgc
atgcatgctgattgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcact
acgtcttccttaaataaacacaggaggttttgtgagggcaagaaccattttgcggcaggt
ggattttttggccaaggcatttcacttcctggaaccccagctatggataaaacgtccatg
gttaatatgggccacgccaacccgggcctggttgactattttggcaccaataggcatcct
gctggtcttacctttccaacagctccgggattttccttgagctttcctggtctgtttcct
tcgggcttgtaccacaggcctcctttgatacccgctagctctcctgttaaaggactatca
agtaccgaacagtcaaacaaatgtcaaagtcccctcttgacacatcctcagatactgcca
gccacccaggatattttgaaggcactatctaaacacccacctgtaggggacaataagcca
gtggaactgctgcccgagaggtcctctgaagagaggccccttgagaaaatcagtgaccag
tcagagagtagtgaccttgatgatgtcagtacgccaagtggcagtgatctggaaacaacc
tcgggctctgatctggaaagtgaccttgaaagtgataaagagaaatgtaaagaaaatggt
aaaatgttcaaagacaaagtaagccctctgcagaatctggcttcaataaataataagaaa
gaatacagcaatcattccgttttctcagcatctgtagaggagcagaccgcggtgtcagga
gctgtgaatgattctataaaggctattgcgtctattgctgaaaaatactttggttccaca
ggactggtggggctgcaagacaaaaaagtcggagcgttaccttacccttccatgtttccc
ctcccgttttttccagcattctctcaatcaatgtacccatttcctgatagagacttgagg
tcgttacctttgaaaatggagccccaatcaccaagtgaagtaaagaaactgcagaaggga
agctctgagtccccttttgacctcaccactaagagaaaggacgagaagcccttgacttca
ggctcctcaaagcttccagcaacacccgccacaagccaagaccagcccctggatctaagt
atgggcagtaggagtagagccagtgggacaaagttgactgagcctcgaaaaaaccatgtg
tttggggaaaagaaaggaagcaacatggaaacaaggccatcttcagatggctccttgcag
catgccagacccactcccttcttcatggatcccatttatagagtagagaaaagaaagctc
actgatccgcttgaagctttgaaagaaaaatacttgagaccttctccaggattcttgttt
cacccacaattcccactacctgaccagagaacatggatgtcggctatcgagaacatggcg
gaaaaactagaaagcttcagcggcctgaaaccagaggccagcgagctcctgcagtcagtg
ccctctatgttcagcttccgggctcctcccaacaccctgccagagaacctgctgcggaag
ggaaaggaacgctatacctgcaggtactgtggtaagattttcccaaggtctgcaaaccta
acacggcatttgagaacccacacaggagagcaaccttacagatgcaaatactgcgataga
tcattcagtatttcctccaacctgcagcgacacgtgcgcaacattcacaacaaggagaag
ccatttaagtgtcacctatgtgacagatgctttggtcaacaaaccaatcttgacagacac
ctgaagaaacacgagaacgggaacatgtctggtacagcaacatcctcgcctcattcggag
ctagaaagcgcaggtgccatcctggatgacaaagaagatgcttactttacagagatccgc
aatttcatcgggaatagcaaccatgggagccagtctcctcggaacatggaggagaggatg
aatggcagtcacttcaaggatgaaaaggctttggcgaccagccaaaattccgatttattg
gatgacgaagaagtagaggatgaggtgttgctggatgaggaggatgaagacaatgatatt
cctggaaaacccagaaaggagctgggggtaactaatttagatgaggaaatccctgaggat
gactatgaggaagccggtgccctggagatgagttgtaaggtgtcccccgtgaggtataaa
gaggaagactataaatctggcctttctgctctagatcacataaggcacttcacagatagc
ctcaaaatgagggaaatggaagagaatcaatacactgacgctgagctgtcctttggttct
tctcatgtgccagaggagcttaaacagccgttacacagaaagtccaaatcacaggcatat
gctatgatgttgtcactgtctgacaaggatgccctccatcccacctcccacggttcctcc
aacgtgtggcacagcatggcaagagctgcagcggaatccagtgccatccagtccataagc
catgtatga
DBGET
integrated database retrieval system
